Oxidized Extracellular DNA as a Stress Signal in Human Cells

Oxidative DNA Damage Is Significantly Correlated With Flow-Mediated Dilation in Patients With Coronary Artery Disease

(2016) Selen Yurdakul et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Emotional Stress in Rats Changes Concentration and Composition of Extracellular DNA Circulating in Blood Plasma under Normal Conditions and in Cerebral Ischemia

(2012) I. L. Konorova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

HMGB1 was a pivotal synergistic effecor for CpG oligonucleotide to enhance the progression of human lung cancer cells

(2012) Chunhong Wang et al.   CANCER BIOLOGY & THERAPY

Immunogenic Tumor Cell Death Induced by Chemoradiotherapy in Patients with Esophageal Squamous Cell Carcinoma

(2012) Yoshiyuki Suzuki et al.   CANCER RESEARCH

Radiation-Induced Stress Proteins - the Role of Heat Shock Proteins (HSP) in Anti- Tumor Responses

(2012) T.E. Schmid et al.   CURRENT MEDICINAL CHEMISTRY

Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: The Vitality 90+ Study

(2012) Juulia Jylhävä et al.   EXPERIMENTAL GERONTOLOGY

Extracellular DNA oxidation stimulates activation of NRF2 and reduces the production of ROS in human mesenchymal stem cells

(2012) Polina Loseva et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Extracellular GC-rich DNA activates TLR9- and NF-kB-dependent signaling pathways in human adipose-derived mesenchymal stem cells (haMSCs)

(2012) Svetlana Kostjuk et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A comparative study of cell-free apoptotic and genomic DNA using FISH and massive parallel sequencing

(2012) Evgeniy S Morozkin et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G0/G1-phase human cells

(2012) M. Gandhi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential gene expression profiles of DNA repair genes in esophageal cancer cells after X-ray irradiation

(2012) Hai Zhang et al.   Chinese Journal of Cancer

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice

(2011) Hiroyuki Yoshida et al.   FREE RADICAL BIOLOGY AND MEDICINE

Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice

(2011) Hai Huang et al.   HEPATOLOGY

Rapid and simple one-step membrane extraction for the determination of 8-hydroxy-2′-deoxyguanosine in human plasma by a combination of on-line solid phase extraction and LC–MS/MS

(2011) Chien-Jen Wang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST

(2011) Stéphanie Lagadu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mitochondrial DNA and anti-mitochondrial antibodies in serum of autistic children

(2011) Bodi Zhang et al.   Journal of Neuroinflammation

Increased plasma levels of extracellular mitochondrial DNA during HIV infection: A new role for mitochondrial damage-associated molecular patterns during inflammation

(2011) Andrea Cossarizza et al.   MITOCHONDRION

An extracellular DNA mediated bystander effect produced from low dose irradiated endothelial cells

(2011) Aleksei V. Ermakov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Role of extracellular DNA oxidative modification in radiation induced bystander effects in human endotheliocytes

(2011) Svetlana V. Kostyuk et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Cell-free Nucleic Acids as Potential Markers for Preeclampsia

(2011) S. Hahn et al.   PLACENTA

The Evaluation of the Oxidative Stress Parameters in Patients with Primary Angle-Closure Glaucoma

(2011) Dong Chang et al.   PLoS One

Radiation-induced bystander effects induce radioadaptive response by low-dose radiation

(2011) M. Ojima et al.   RADIATION PROTECTION DOSIMETRY

Long-Term Consequences of Radiation-Induced Bystander Effects Depend on Radiation Quality and Dose and Correlate with Oxidative Stress

(2011) Manuela Buonanno et al.   RADIATION RESEARCH

Radiation-Induced Bystander Effects: What Are They, and How Relevant Are They to Human Radiation Exposures?

(2011) Benjamin J. Blyth et al.   RADIATION RESEARCH

Non-targeted effects of ionising radiation and radiotherapy

(2010) Svetlana Sjostedt et al.   AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE

The redox protein HMGB1 regulates cell death and survival in cancer treatment

(2010) Daolin Tang et al.   Autophagy

Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers

(2010) Randa A El-Zein et al.   BMC CANCER

Enhanced Expression of iNOS in Human Endothelial Cells during Long-Term Culturing with Extracellular DNA Fragments

(2010) S. V. Kostyuk et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Extracellular DNA Affects NO Content in Human Endothelial Cells

(2010) L. V. Efremova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease

(2010) A. Szaflarska-Poplawska et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Correlation between concentrations of 8-oxo-7,8-dihydro-2′-deoxyguanosine in urine, plasma and saliva measured by on-line solid-phase extraction LC-MS/MS

(2010) Chiung-Wen Hu et al.   CLINICA CHIMICA ACTA

Cell-free plasma DNA and purine nucleotide degradation markers following weightlifting exercise

(2010) Johanna Atamaniuk et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Micronucleus frequency in lymphocytes and 8-hydroxydeoxyguanosine level in plasma of women with polycystic ovary syndrome

(2010) Zuhal Hamurcu et al.   GYNECOLOGICAL ENDOCRINOLOGY

No increased chromosomal damage in l-DOPA-treated patients with Parkinson’s disease: a pilot study

(2010) Rajaraman Gnana Oli et al.   JOURNAL OF NEURAL TRANSMISSION

Increased concentrations of the oxidative DNA adduct 7,8-dihydro-8-oxo-2-deoxyguanosine in the germ-line of men with type 1 diabetes

(2010) IM Agbaje et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Circulating DNA

(2009) Maniesh van der Vaart et al.   Annals of the New York Academy of Sciences

Extracellular DNA Fragments

(2009) Aleksei V. Ermakov et al.   Annals of the New York Academy of Sciences

Effect of Cell-Free DNA of Patients with Cardiomyopathy and rDNA on the Frequency of Contraction of Electrically Paced Neonatal Rat Ventricular Myocytes in Culture

(2009) N. Bulicheva et al.   Annals of the New York Academy of Sciences

Selenium Supplementation Reduced Oxidative DNA Damage in Adnexectomized BRCA1 Mutations Carriers

(2009) T. Dziaman et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress

(2009) Dipti Mangal et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy

(2009) Joanna Rzeszowska-Wolny et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

(2009) Zubin M. Bamboat et al.   HEPATOLOGY

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 loves company

(2009) Marco E. Bianchi   JOURNAL OF LEUKOCYTE BIOLOGY

Oxidative stress as a significant factor for development of an adaptive response in irradiated and nonirradiated human lymphocytes after inducing the bystander effect by low-dose X-radiation

(2009) Aleksei V. Ermakov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

The change of oxidative stress products in diabetes mellitus and diabetic retinopathy

(2008) H.-Z. Pan et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Effect of intensive lipid-lowering therapy on telomere erosion in endothelial progenitor cells obtained from patients with coronary artery disease

(2008) Mamoru Satoh et al.   CLINICAL SCIENCE

Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?

(2008) Steffen Loft et al.   EUROPEAN JOURNAL OF NUTRITION

Blood oxidative stress biomarkers: influence of sex, exercise training status, and dietary intake

(2008) Richard J. Bloomer et al.   Gender Medicine

Mechanism of radiation-induced bystander effects: a unifying model

(2008) Tom K. Hei et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The relationship between 8-oxo-7,8-dihydro-2′-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas

(2008) Jolanta Guz et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo

(2007) Sanjeev Pathak et al.   CANCER LETTERS