Riluzole-Triggered GSH Synthesis via Activation of Glutamate Transporters to Antagonize Methylmercury-Induced Oxidative Stress in Rat Cerebral Cortex

Regulation of xCT expression and system $$ x_{\text{c}}^{ - } $$ function in neuronal cells

(2011) Jan Lewerenz et al.   AMINO ACIDS

Microglial self-defence mediated through GLT-1 and glutathione

(2011) Mikael Persson et al.   AMINO ACIDS

Toward a new role for plasma membrane sodium-dependent glutamate transporters of astrocytes: maintenance of antioxidant defenses beyond extracellular glutamate clearance

(2011) Laurence Had-Aissouni   AMINO ACIDS

EAAT expression by macrophages and microglia: still more questions than answers

(2011) Gabriel Gras et al.   AMINO ACIDS

Modulation of neuronal glutathione synthesis by EAAC1 and its interacting protein GTRAP3-18

(2011) Koji Aoyama et al.   AMINO ACIDS

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Loss of System xFormula Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility

(2011) D. De Bundel et al.   JOURNAL OF NEUROSCIENCE

Riluzole elevates GLT-1 activity and levels in striatal astrocytes

(2011) Marica Carbone et al.   NEUROCHEMISTRY INTERNATIONAL

Oxidative stress in MeHg-induced neurotoxicity

(2011) Marcelo Farina et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Complex Methylmercury-Cysteine Alters Mercury Accumulation in Different Tissues of Mice

(2010) Daniel Henrique Roos et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

A Review of the Neural Mechanisms of Action and Clinical Efficiency of Riluzole in Treating Amyotrophic Lateral Sclerosis: What have we Learned in the Last Decade?

(2010) Mark C. Bellingham   CNS Neuroscience & Therapeutics

Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

(2010) B.C. Cheah et al.   CURRENT MEDICINAL CHEMISTRY

Methylmercury Induces Acute Oxidative Stress, Altering Nrf2 Protein Level in Primary Microglial Cells

(2010) Mingwei Ni et al.   TOXICOLOGICAL SCIENCES

The protective effect of riluzole on manganese caused disruption of glutamate–glutamine cycle in rats

(2009) Yu Deng et al.   BRAIN RESEARCH

Methylmercury induces neuropathological changes with tau hyperphosphorylation mainly through the activation of the c-jun-N-terminal kinase pathway in the cerebral cortex, but not in the hippocampus of the mouse brain

(2009) Masatake Fujimura et al.   NEUROTOXICOLOGY

Enhanced endogenous type I interferon cell-driven survival and inhibition of spontaneous apoptosis by Riluzole

(2009) Ammar Achour et al.   VIROLOGY

Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity

(2008) Jianfeng Liang et al.   BRAIN RESEARCH

Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1

(2007) Elena Fumagalli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain

(2007) James Stringari et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY