Prevention of Diabetic Nephropathy by Sulforaphane: Possible Role of Nrf2 Upregulation and Activation

Prevention of Diabetic Complications by Activation of Nrf2: Diabetic Cardiomyopathy and Nephropathy

(2012) Bing Li et al.   Experimental Diabetes Research

Attenuation of Glomerular Injury in Diabetic Mice with Tert-Butylhydroquinone through Nuclear Factor Erythroid 2-Related Factor 2-Dependent Antioxidant Gene Activation

(2011) Hang Li et al.   AMERICAN JOURNAL OF NEPHROLOGY

Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage

(2011) Junling Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

(2011) P. Palsamy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diabetic nephropathy in humans: pathologic diversity

(2011) Elisabeth JJ Valk et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Mouse models of diabetic nephropathy

(2011) Charles E Alpers et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Nrf2 Activators as Attractive Therapeutics for Diabetic Nephropathy: FIG. 1.

(2011) Judy B. de Haan   DIABETES

Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

(2011) Hongting Zheng et al.   DIABETES

Prevention of diabetic nephropathy in rats through enhanced renal antioxidative capacity by inhibition of the proteasome

(2011) Zhi-Feng Luo et al.   LIFE SCIENCES

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

(2011) John D. Clarke et al.   PHARMACEUTICAL RESEARCH

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

(2010) Gerasimos P Sykiotis et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Protective effect of sulforaphane against oxidative stress: Recent advances

(2010) Carlos Enrique Guerrero-Beltrán et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

The NRF2–heme oxygenase-1 system modulates cyclosporin A-induced epithelial–mesenchymal transition and renal fibrosis

(2010) Dong-ha Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inactivation of GSK-3  by Metallothionein Prevents Diabetes-Related Changes in Cardiac Energy Metabolism, Inflammation, Nitrosative Damage, and Remodeling

(2009) Y. Wang et al.   DIABETES

Oxidative Stress, Diabetes, and Diabetic Complications

(2009) Wei Wei et al.   HEMOGLOBIN

Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

(2008) Masaru Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme

(2008) Ha-Yong Yoon et al.   BIOCHEMICAL PHARMACOLOGY

Activation of NF-E2-Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

(2008) M. Xue et al.   DIABETES

Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice

(2008) Keigyou Yoh et al.   GENES TO CELLS

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

(2008) Xiaoqing He et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Metallothionein Suppresses Angiotensin II–Induced Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation, Nitrosative Stress, Apoptosis, and Pathological Remodeling in the Diabetic Heart

(2008) Guihua Zhou et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY