Tirapazamine-Doxorubicin Interaction Referring to Heart Oxidative Stress and Ca2+Balance Protein Levels

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Oxidative stress impairs insulin signal in skeletal muscle and causes insulin resistance in postinfarct heart failure

(2011) Yukihiro Ohta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms and management of doxorubicin cardiotoxicity

(2011) Y. Shi et al.   HERZ

Redox Signaling and Cardiac Sarcomeres

(2011) Marius P. Sumandea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of reactive oxygen species in the regulation of cardiac contractility

(2011) Anna-Maria Kubin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Proanthocyanidins Produce Significant Attenuation of Doxorubicin-Induced Mutagenicity via Suppression of Oxidative Stress

(2011) Sabry M. Attia et al.   Oxidative Medicine and Cellular Longevity

Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation

(2011) Othman A. Alshabanah et al.   Oxidative Medicine and Cellular Longevity

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy

(2010) Y. Zhao et al.   CANCER RESEARCH

Inhibition of gene expression of heart fatty acid binding protein and organic cation/carnitine transporter in doxorubicin cardiomyopathic rat model

(2010) Mohamed M. Sayed-Ahmed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Doxorubicin induces mitochondrial permeability transition and contractile dysfunction in the human myocardium

(2010) David Montaigne et al.   MITOCHONDRION

Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation

(2010) Amy V. Pointon et al.   PLoS One

Cardiomyocyte death in doxorubicin-induced cardiotoxicity

(2009) Yi-Wei Zhang et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats

(2009) Karol L. Thompson et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy

(2009) Jaya Krishnan et al.   Cell Metabolism

Cardiotoxicity after anthracycline chemotherapy in breast carcinoma: Effects on left ventricular ejection fraction, troponin I and brain natriuretic peptide

(2009) Mauro Feola et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation

(2009) Bo Hong et al.   INVESTIGATIONAL NEW DRUGS

Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets

(2008) Vilma A. Sardão et al.   CELL BIOLOGY AND TOXICOLOGY

Tirapazamine: a novel agent targeting hypoxic tumor cells

(2008) Srini B Reddy et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS