Article
Medicine, General & Internal
Anda Gata, Corneliu Toader, Veronica Elena Trombitas, Annamaria Ilyes, Silviu Albu
Summary: This study analyzed successful closure of defects in 20 patients with pneumocephalus and CSF leaks through endoscopic skull base repair. The study suggests early endoscopic endonasal treatment for patients with CSF leaks and pneumocephalus.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Abdulrazag Ajlan, Sarah Basindwah, Aysha Hawsawi, Mohammed Ali Omar, Saad Alsaleh, Abdulaziz Alrasheed, Ahmad Alroqi, Ashwag Alqurashi
Summary: This study found that the volume and location of pneumocephalus in the early postoperative period of endoscopic skull base surgery (ESBS) are potentially predictive of cerebrospinal fluid (CSF) leak. Patients with larger volumes of intra-axial air and/or multiple air locations are more likely to develop CSF leak.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Christopher D. Pool, Vijay A. Patel, Gloria Hwang, Jeremy Barr, Neerav Goyal
Summary: This study validated the use of topical intranasal fluorescein for CSF detection, finding that color change alone is not sufficient to distinguish between CSF, saliva, and saline, but can readily identify blood.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Moritz Ueberschaer, Sophie Katzendobler, Annamaria Biczok, Michael Schmutzer, Tobias Greve, Joerg-Christian Tonn, Jun Thorsteinsdottir, Walter Rachinger
Summary: The transsphenoidal approach is the standard for treating pituitary adenomas, and using synthetic materials for CSF leak repair and sellar closure can significantly reduce the risk of CSF fistulas and meningitis.
NEUROSURGICAL FOCUS
(2022)
Article
Medicine, Research & Experimental
Satyan B. Sreenath, Dennis M. Tang, Jonathan Y. Ting, Elisa A. Illing, Pablo F. Recinos, Pranay Soni, Varun R. Kshettry, Aaron Cohen-Gadol, Troy D. Woodard, Raj Sindwani
Summary: The study reports a multi-institutional experience of using a simplified, endoscopic modified transpterygoid approach for lateral sphenoid sinus meningoencephaloceles and CSF leaks. The approach reduces morbidity, simplifies access, and achieves a 100% success rate without compromising exposure. Postoperative complications were rare, making it a feasible option for managing benign lesions involving the lateral sphenoid sinus.
Article
Clinical Neurology
Daryl Fields, Michael McDowell, Anthony Schulien, Hanna Algattas, Hussam Abou-Al-Shaar, Nitin Agarwal, Nima Alan, Tina Costacou, Eric Wang, Carl Snyderman, Paul Gardner, Georgios Zenonos
Summary: Low preoperative prealbumin levels are an independent predictor of postoperative cerebrospinal fluid leak and infection in endoscopic endonasal skull base surgery.
WORLD NEUROSURGERY
(2022)
Article
Clinical Neurology
Alex P. Michael, Osama Elbuluk, Apostolos John Tsiouris, Abtin Tabaee, Ashutosh Kacker, Vijay K. Anand, Theodore H. Schwartz
Summary: The use of vascularized flaps in endonasal repair can significantly reduce the recurrence rate of spontaneous CSF leaks; Patients with higher BMI, larger brain herniations, and no CSF diversion are more likely to experience recurrence.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Cathal John Hannan, Bharti Kewlani, Steven Browne, Mohsen Javadpour
Summary: This study reviewed a large series of endoscopic skull base cases and found that the adoption of a standardized multi-layer repair technique significantly reduced the post-operative CSF leak rate, without the use of nasal packing or lumbar drains.
ACTA NEUROCHIRURGICA
(2023)
Article
Surgery
J. F. Villalonga, D. Solari, R. Cuocolo, V. De Lucia, L. Ugga, C. Gragnaniello, J. I. Pailler, A. Cervio, A. Campero, L. M. Cavallo, P. Cappabianca
Summary: This study validates the application of the sellar barrier concept for predicting intraoperative cerebrospinal fluid (CSF) leak in endoscopic endonasal surgery for pituitary adenomas using a machine learning approach. The results show a true correlation between the type of sellar barrier at MRI and its in vivo features observed during surgery.
FRONTIERS IN SURGERY
(2022)
Article
Multidisciplinary Sciences
Vlastimil Novak, L. Hrabalek, J. Hoza, C. Hucko, D. Pohlodek, J. Macura
Summary: The endoscopic endonasal approach for patients with a sellar tumor is a gentle method with minimal impact on sinonasal quality of life over a period longer than six months. Common complaints post-surgery include the need to blow nose, nasal congestion, loss of smell and taste, and thick discharge from the nose. Cranial base reconstruction using muscle and fascia lata appears to positively influence sinonasal quality of life.
SCIENTIFIC REPORTS
(2021)
Article
Otorhinolaryngology
Roberto M. Soriano, Rima S. Rindler, Samuel N. Helman, Gustavo Pradilla, C. Arturo Solares
Summary: The study demonstrates the feasibility of endoscopic transoral nasopharyngectomy (ETON) for resection of large nasopharyngeal lesions, providing wide exposure of the skull base and proximal control of the internal carotid artery. It may be beneficial for managing nasopharyngeal tumors with inferolateral extension involving the internal carotid artery.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Otorhinolaryngology
Karan Jolly, Keshav Kumar Gupta, Abishek Banota, Shahzada K. Ahmed
Summary: The study evaluated the safety and efficacy of intrathecal fluorescein (IF) use in the management of CSF leak repairs in a UK tertiary skull base referral unit. Results showed a positive localisation rate of 90% with IF, with an overall peri-operative complication rate of 8.3% and potentially IF-related complication rate of 5.0%. No serious complications such as seizures, limb weakness, or death were directly attributable to IF use, indicating that IF use in CSF fistula repairs is safe and effective.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2021)
Article
Medicine, Research & Experimental
Justin P. McCormick, Ashwini Tilak, H. Brooks Lampkin, Harrison M. Thompson, Peter L. Miller, John M. West, Do-Yeon Cho, Kristen O. Riley, Jessica W. Grayson, Bradford A. Woodworth
Summary: This study evaluated the safety and utility of an expedited protocol for recording and managing intracranial hypertension following endoscopic repair of spontaneous CSF leaks. The results showed that the expedited monitoring protocol shortened hospital stay without increased risk of complications.
Article
Otorhinolaryngology
Neal R. Godse, Satyan B. Sreenath, Firas Sbeih, Troy D. Woodard, Varun R. Kshettry, Pablo F. Recinos, Raj Sindwani
Summary: This study retrospectively reviewed 50 patients who underwent skull base reconstruction using fascia lata (FL). The results showed that FL is a versatile option for the reconstruction of challenging defects with excellent outcomes and minimal morbidity.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2023)
Article
Otorhinolaryngology
Satyan B. Sreenath, Dennis M. Tang, Joao Paulo De Almeida, Pranay Soni, Troy D. Woodard, Pablo F. Recinos, Varun R. Kshettry, Raj Sindwani
Summary: The MTPA is a quicker and less invasive approach to the lateral sphenoid recess which preserves the PPF contents, simplifying access and minimizing postoperative morbidity.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2021)