Review
Medicine, General & Internal
Fangfang Ma, Hewei Zhang, Bingxue Li, Peiyu Cheng, Yunfei Ma, Mingwei Yu, Xiaomin Wang
Summary: This study aims to evaluate the effects of Traditional Chinese Medicine on Post-viral olfactory dysfunction (PVOD). The systematic evaluation may offer more reliable evidence-based medical evidence for clinical practice, assisting patients in relieving PVOD.
Article
Medicine, General & Internal
Shu Kikuta, Bing Han, Tatsuya Yamasoba
Summary: The objective of this study was to determine if olfactory sensory neurons are uniformly damaged in PVOD. Comparing PVOD patients with CRS and PTOD patients, it was found that a response to a single odor is characteristic of PVOD, while there were no significant abnormalities in the response to five different odors. In mouse experiments, it was found that a single odor selectively activated one type of sensory neurons, while five different odors activated both types of sensory neurons simultaneously.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Otorhinolaryngology
Chunhua Hu, Yang Gao, Yanjun Feng, Zhifu Sun, Zhan Yu
Summary: This study investigates the factors influencing the volume of the olfactory bulb in patients with post-viral olfactory dysfunction. The study found that male patients had larger olfactory bulb volume, longer duration of olfactory dysfunction resulted in smaller olfactory bulb volume, and higher score of anterior ethmoidal sinusitis led to smaller olfactory bulb volume.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Review
Clinical Neurology
Michael S. Xydakis, Mark W. Albers, Eric H. Holbrook, Dina M. Lyon, Robert Y. Shih, Johannes A. Frasnelli, Axel Pagenstecher, Alexandra Kupke, Lynn W. Enquist, Stanley Perlman
Summary: COVID-19 is often associated with olfactory dysfunction, providing a research opportunity to study the natural course of this neurological finding. However, limited by sample sizes and lack of advanced neuroimaging data, there is still a substantial gap in knowledge regarding the mechanisms of olfactory impairment. Persistent olfactory deficits post-SARS-CoV-2 infection could potentially be a marker for increased long-term risk of neurological disease.
Article
Clinical Neurology
Akira Morita, Aya Murakami, Takushu Uchihara, Noriyuki Ohashi, Koichi Ryu, Yuki Watanabe, Sadayuki Ochi, Kazuho Okudaira, Yoshiro Hirasaki, Takao Namiki
Summary: This article describes two cases of olfactory dysfunction in the post COVID-19 condition that were improved by traditional acupuncture treatment. Acupuncture treatment using the Yingxiang point (LI20) was performed 1-2 times a week for 6-7 months after COVID-19 diagnosis. Acupuncture was found to be effective in alleviating symptoms of olfactory dysfunction in a short period of time, suggesting it as a new option for patients resistant to medical treatment.
FRONTIERS IN NEUROLOGY
(2022)
Review
Pharmacology & Pharmacy
Ming Lyu, Guanwei Fan, Guangxu Xiao, Taiyi Wang, Dong Xu, Jie Gao, Shaoqin Ge, Qingling Li, Yuling Ma, Han Zhang, Jigang Wang, Yuanlu Cui, Junhua Zhang, Yan Zhu, Boli Zhang
Summary: The COVID-19 pandemic poses a significant threat to global public health and safety, with the crucial role and potential mechanisms of Traditional Chinese Medicine (TCM) in combination with Western medicine highlighted and discussed. A comprehensive review of the clinical effects and potential mechanisms of TCM on COVID-19 is presented, aiming to provide reference for healthcare professionals and the public, and facilitate understanding of the true scientific value of TCM.
ACTA PHARMACEUTICA SINICA B
(2021)
Review
Pharmacology & Pharmacy
Yanfei Feng, Tianhao Shi, Yuli Fu, Bodong Lv
Summary: Diabetic erectile dysfunction (DED) is a common complication of diabetes mellitus, but current therapeutics have limited effectiveness. Traditional Chinese medicine (TCM) has shown promise in treating DED by targeting multiple signaling pathways. However, more research is needed to fully understand the underlying mechanisms and conduct large-scale clinical trials.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Zhihua Yang, Shanshan Lin, Yangxi Liu, Qiuan Ren, Zhao Ge, Ci Wang, Yingfei Bi, Xianliang Wang, Jingyuan Mao
Summary: Coronary microvascular disease (CMVD) is common in patients with cardiovascular risk factors and is associated with an increased risk of adverse cardiovascular events. Traditional Chinese medicine (TCM), with its clinical advantages of syndrome differentiation and individualized treatment, shows potential efficacy and action mechanisms for CMVD. However, there are still many scientific issues and gaps in the research of CMVD.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Neurosciences
Cheng-Yu Tseng, Pei-Shan Hsu, Chang-Ti Lee, Hui-Fen Huang, Chou-Chin Lan, Tsung-Han Hsieh, Guan-Ting Liu, Chan-Yen Kuo, Ming-Chieh Wang, Po-Chun Hsieh
Summary: The integration of acupuncture and traditional Chinese herbal medicine with conventional rehabilitation has been found to significantly improve functional recovery in stroke patients, particularly those with poor activities of daily living (ADL).
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Medicine, Research & Experimental
Aytug Altundag, Ozlem Saatci, Sedat G. Kandemirli, Deniz E. T. Sanli, Ozge A. Duz, Ahmet N. Sanli, Duzgun Yildirim
Summary: A retrospective study on 52 patients undergoing olfactory training for post-traumatic olfactory dysfunction revealed imaging features that can predict responses to treatment. A scoring system was developed based on five variables to provide a good specificity for optimizing management options.
Article
Radiology, Nuclear Medicine & Medical Imaging
Duzgun Yildirim, Sedat Giray Kandemirli, Deniz Esin Tekcan Sanli, Ozlem Akinci, Aytug Altundag
Summary: This study evaluated the imaging findings of COVID-19 related anosmia and compared them with post-infectious anosmia. The results showed significantly higher olfactory bulb volumes in COVID-19 related anosmia patients compared to post-infectious anosmia patients, which may be related to differences in central olfactory system damage.
ACADEMIC RADIOLOGY
(2022)
Article
Multidisciplinary Sciences
Xin Chen, Fayang Wang, Yanjun Zhao, Pengfan Wu, Lingxiao Gao, Chun Ouyang, Ya Yang, Xiaojing Mu
Summary: This study investigates the improvement of the output performance of triboelectric nanogenerator (TENG) by using core-shell nanoparticles. The findings show the potential application of this technology in traditional Chinese medicine and healthcare platforms.
Article
Otorhinolaryngology
Yichen Guo, Dawei Wu, Zhifu Sun, Linyin Yao, Jia Liu, Yongxiang Wei
Summary: This study showed that event-related potentials (ERPs), duration of olfactory dysfunction (OD), and initial threshold were associated with olfactory improvement in patients with post-infectious olfactory dysfunction (PIOD). These findings may provide guidance for clinicians in developing more effective treatment plans.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Review
Otorhinolaryngology
Jason C. Lee, Rohit Nallani, Lauren Cass, Vidur Bhalla, Alexander G. Chiu, Jennifer A. Villwock
Summary: This study reviewed existing primary literature related to post-viral olfactory dysfunction, highlighting the underlying pathophysiological mechanisms and future research directions, emphasizing the relevance to the current COVID-19 pandemic. It was found that viral effects on the olfactory system vary significantly based on viral substrain, generally involving damage or alteration in components of the olfactory epithelium and/or the olfactory bulb.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2021)
Review
Otorhinolaryngology
Tianhao Huang, Yongxiang Wei, Dawei Wu
Summary: Posttraumatic olfactory dysfunction poses a clinical challenge with limited treatment options. Olfactory training has been proven effective for patients with this condition, showing significant improvements in olfactory performance. Additional high-quality studies with controls are needed to further explore the effects of olfactory training on total olfactory function and specific components.
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
(2021)
