Article
Otorhinolaryngology
Jodi Hernandez, Glen Leverson, Susan Thibeault
Summary: The study found that patients prefer atomized lidocaine for increased comfort during pharyngeal high-resolution manometry procedures. While no significant differences were detected in pharyngeal pressure measurements between the two groups, the use of atomized lidocaine did not affect measurement outcomes.
Article
Medicine, Research & Experimental
Seh Ling Kwong, Ester G. Hernandez, Katharina Winiker, Kristin Gozdzikowska, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study examined the effect of topical nasal anesthetic (TNA) on swallowing and tolerability during high-resolution impedance manometry (HRIM) with a 4.2-mm catheter. The results showed that TNA did not improve comfort or significantly affect swallowing behavior during the procedure.
Article
Engineering, Biomedical
Miho Ohashi, Yoichiro Aoyagi, Satoshi Ito, Hitoshi Kagaya, Masatoshi Hirata, Seiichi Nakata
Summary: This study assessed the accuracy and efficiency of high-resolution manometry (HRM) topography, electromyography (EMG), sound, and bioimpedance waveforms for identifying swallowing events. The results showed that HRM topography had the highest classification accuracy, followed by sound and bioimpedance waveforms, while EMG waveform had the lowest classification accuracy. Therefore, HRM, sound, bioimpedance, and EMG are potential methods for counting swallowing events in screening for dysphagia, but further study is needed.
MEDICAL ENGINEERING & PHYSICS
(2023)
Article
Pediatrics
Anna Maria Caruso, Denisia Bommarito, Vincenza Girgenti, Glenda Amato, Adele Figuccia, Alessandra Casuccio, Annalisa Ferlisi, Rosaria Genuardi, Sabrina La Fata, Rosalia Mattei, Mario Pietro Marcello Milazzo, Maria Rita Di Pace
Summary: This study analyzed swallowing functions in neurologically impaired (NI) children using esophageal high-resolution manometry (HRM) and established swallow parameters identifying inhalation risk. The results showed alterations in swallowing functions in NI children, which could predispose them to increased inhalation risk.
Article
Otorhinolaryngology
K. Fujiwara, S. Koyama, K. Taira, K. Kawamoto, T. Fukuhara, H. Takeuchi
Summary: Transoral robotic surgery is considered as a less morbid alternative to chemoradiation for oropharyngeal cancer patients. This study used high-resolution manometry to assess the impact of surgery on swallowing function, and found that while there was no significant difference in pharyngeal pressure or contractile integral pre- versus post-operatively, pharyngeal velocity increased significantly after surgery.
JOURNAL OF LARYNGOLOGY AND OTOLOGY
(2021)
Article
Multidisciplinary Sciences
Sudarshan R. Jadcherla, Kathryn A. Hasenstab, Erika K. Osborn, Deborah S. Levy, Haluk Ipek, Roseanna Helmick, Zakia Sultana, Nicole Logue, Vedat O. Yildiz, Hailey Blosser, Summit H. Shah, Lai Wei
Summary: This study demonstrates that an integrated approach with parent-preferred therapy based on mechanistic understanding of VFSS and HRM metrics improves oral feeding outcomes, despite evidence of penetration or aspiration. The application of new knowledge of the physiology of swallowing and airway protection may contribute to these findings.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Chih-Jun Lai, Ya-Jung Cheng, Dar-Ming Lai, Chun-Yu Wu, Wen-Ting Chang, Fon-Yih Tsuang
Summary: Objective assessment of perioperative swallowing changes is crucial for patients undergoing ACSS. HRIM was used to evaluate swallowing objectively, and the results showed a significant increase in SRI on postoperative day 1, followed by recovery on day 7. This study demonstrated that HRIM is superior to DSQ in detecting mechanisms and monitoring the recovery from swallowing dysfunction.
FRONTIERS IN SURGERY
(2022)
Article
Gastroenterology & Hepatology
Ming-Wun Wong, Chih-Hsun Yi, Tso-Tsai Liu, Wei-Yi Lei, Jui-Sheng Hung, Chao-Zong Liu, Chien-Lin Chen
Summary: This study investigated the effects of sildenafil on secondary peristalsis using HRM and found that sildenafil reduces the success rate and vigor of secondary peristalsis, similar to its effects on primary peristalsis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Wei-Yi Lei, Jui-Sheng Hung, Taher Omari, Charles Cock, Shu-Wei Liang, Chandra Prakash Gyawali, Chien-Lin Chen
Summary: This study aimed to evaluate the feasibility and usefulness of CSI with SLR in complementing the diagnosis of GERD. Results showed that impedance-based metrics were lower in GERD patients compared to non-GERD patients. Particularly, the SLR maneuver increased diagnostic accuracy of CSI for GERD identification, especially in IEM patients.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Gastroenterology & Hepatology
Roberto Penagini, Nicola de Bortoli, Edoardo Savarino, Elena Arsie, Salvatore Tolone, Garrett Greenan, Pierfrancesco Visaggi, Daria Maniero, Aurelio Mauro, Dario Consonni, C. Prakash Gyawali
Summary: RDC during high-resolution manometry is an effective surrogate for TBE in assessing esophageal emptying in treated patients with achalasia.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Chien-Lin Chen, Ming-Wun Wong, Jui-Sheng Hung, Shu-Wei Liang, Tso-Tsai Liu, Chih-Hsun Yi, Lin Lin, William C. Orr, Wei-Yi Lei
Summary: The study investigated the effects of acute administration of codeine on primary and secondary peristalsis in healthy adults. Results showed that codeine increased the relaxation pressure and frequency of secondary peristalsis, while also affecting primary peristalsis by increasing relaxation pressure and shortening distal latency. This suggests that opioids like codeine can impact both primary and secondary peristalsis in the esophagus.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Otorhinolaryngology
Yoshihiko Kumai, Takumi Miyamoto, Keigo Matsubara, Chisei Satoh, Satoshi Yamashita, Yorihisa Orita
Summary: This study compared oropharyngeal swallowing dysfunction in myasthenia gravis (MG) patients presenting with difficulty in swallowing between the neutral and chin-down positions using high-resolution manometry (HRM) examination. The chin-down position was found to be beneficial in improving pharyngeal clearance in MG patients by increasing swallowing pressure at the meso-hypopharynx, relaxing pressure at the upper esophageal sphincter (UES), and prolonging the duration of relaxation pressure at the UES.
AURIS NASUS LARYNX
(2021)
Article
Medicine, Research & Experimental
Ilan Palte, Sarah Stewart, Hal Rives, James A. Curtis, Necati Enver, Andrew Tritter, Katerina Andreadis, Valentina Mocchetti, Felice Schnoll-Sussman, Amir Soumekh, Rasa Zarnegar, Philip Katz, Anais Rameau
Summary: The study aimed to investigate the effects of using virtual reality (VR) on pain and anxiety in patients with dysphagia undergoing high-resolution esophageal manometry (HRM). The results showed that the use of VR significantly reduced anxiety and physiological pain responses, suggesting that VR can be used as a distraction tool to improve patient comfort during HRM.
Article
Audiology & Speech-Language Pathology
Niall Heslin, Julie Regan
Summary: This study found that effortful swallowing significantly affects the pharyngeal swallowing biomechanics in adults with dysphagia, including an increase in pharyngeal contractile and opening duration. This suggests that effortful swallowing can improve swallowing difficulties and warrants further investigation in larger clinical populations.
INTERNATIONAL JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2022)
Article
Gastroenterology & Hepatology
Wei-Yi Lei, Shu-Wei Liang, Jui-Sheng Hung, Ming-Wun Wong, Tso-Tsai Liu, Chih-Hsun Yi, Lin Lin, William C. Orr, Chien-Lin Chen
Summary: Intraluminal infusion of menthol reduces upper esophageal sphincter basal pressure and inhibits the frequency of secondary peristalsis. Although menthol modulates esophageal peristalsis, it does not alter other esophageal motility characteristics significantly.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)