Article
Otorhinolaryngology
L. Lopez, P. Garcia-Cabo, J. L. Llorente, F. Lopez, J. P. Rodrigo
Summary: This study aims to describe the outcomes of salvage surgery in patients with locally advanced head and neck squamous cell carcinoma. The results showed that patients with nodal persistence/recurrence have a poor prognosis, but in a substantial number of patients, the disease can be controlled after salvage neck dissection.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Otorhinolaryngology
Sarah J. M. Burgin, Matthew E. Spector, Alexander T. Pearson, Emily Bellile, Jeffrey M. Vainshtein, Andrew Rosko, Scott A. Mclean, Carol R. Bradford, Gregory T. Wolf, Mark E. Prince, Francis P. Worden, Avraham Eisbruch, Douglas B. Chepeha
Summary: The study examined the long-term neck and shoulder impairment in patients treated with primary chemoradiotherapy, finding that the pre-treatment gross tumor nodal volume was a significant predictor of neck and shoulder dysfunction, impacting various aspects of neck and shoulder function.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Review
Endocrinology & Metabolism
Zeyu Zhang, Botao Sun, Hui Ouyang, Rong Cong, Fada Xia, Xinying Li
Summary: Endoscopic lateral neck dissection is a safe and effective technique in thyroid surgery, offering excellent cosmetic outcomes and minimal invasiveness. It allows access to remote sites without the need for extended cervical incisions.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Otorhinolaryngology
Wataru Okano, Ryuichi Hayashi, Kazuto Matsuura, Takeshi Shinozaki, Toshifumi Tomioka
Summary: The study indicates that targeted neck dissection (ND) after definitive chemoradiotherapy is an effective intervention for patients with cervical disease recurrence, showing promising survival rates and control rates.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Oncology
Stephanie M. Ntoukas, Margaret L. McNeely, Hadi Seikaly, Daniel O'Connell, Kerry S. Courneya
Summary: The study aimed to explore the feasibility and safety of heavy lifting strength training (HLST) in head and neck cancer survivors (HNCS). The results showed that HLST led to meaningful improvements in muscular strength for survivors and no adverse events were reported. Future research should consider additional recruitment strategies and compare HLST to light-to-moderate intensity strength training (LMST) in this population.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Medical Laboratory Technology
Yaqi Wang, Xiaojun Fan, Hua Bao, Fan Xia, Juefeng Wan, Lijun Shen, Yan Wang, Hui Zhang, Yulin Wei, Xue Wu, Yang Shao, Xinxiang Li, Ye Xu, Sanjun Cai, Zhen Zhang
Summary: The combination of 5'-end motif profile with mrTRG has the potential to predict the response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.
CLINICAL CHEMISTRY
(2023)
Article
Oncology
Nandini S. Menon, Vanita Noronha, Vijay Maruti Patil, Amit Joshi, Atanu Bhattacharjee, Devanshi Kalra, Sarbani Ghosh Laskar, Vijayalakshmi Mathrudev, Kavita Nawale, Arati S. Bhelekar, Kumar Prabhash
Summary: This study found that the use of once-every-3-weeks cisplatin with radiation did not have a negative impact on the quality of life for patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC), compared to once-a-week cisplatin. However, there were significant differences in the scales of constipation, reduced sexuality, and financial difficulty between the two treatment arms.
Article
Multidisciplinary Sciences
Karthik Murugiah, Lian Chen, Rachel P. Dreyer, Georgios Bouras, Basmah Safdar, Rohan Khera, Yuan Lu, Erica S. Spatz, Vivian G. Ng, Aakriti Gupta, Hector Bueno, Marysia S. Tweet, John A. Spertus, Sharonne N. Hayes, Alexandra Lansky, Harlan M. Krumholz
Summary: This study found that patients with spontaneous coronary artery dissection (SCAD) have better health status outcomes compared to other acute myocardial infarction patients (AMI), and exhibit similar recovery after 12 months.
Article
Multidisciplinary Sciences
Jia Wang, Xuan Su, Xing Zhang, Wenkuan Chen, Jibin Li, Zhongyuan Yang, Xiyuan Li, Jingtao Chen, Ying Zhang, Shuwei Chen, Ming Song
Summary: This study suggests that postoperative radiotherapy (PORT) to the neck does not improve survival in patients with pN1 status head and neck squamous cell carcinomas (HNSCC) after neck dissection. Prospective randomized clinical trials are needed to confirm these findings.
SCIENTIFIC REPORTS
(2022)
Article
Otorhinolaryngology
Joshua B. Smith, Prerana Jayanth, Scott A. Hong, Matthew C. Simpson, Sean T. Massa
Summary: Uninsured individuals aged 55-64 have worse outcomes compared to their insured counterparts. Adequate coverage can prevent these delays. This study investigates the impact of Medicare on the diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC).
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2023)
Review
Oncology
Ivry Zagury-Orly, Nader Khaouam, Jonathan Noujaim, Martin Y. Desrosiers, Anastasios Maniakas
Summary: Radiation and chemoradiation therapy are crucial in head and neck cancer treatment but have adverse effects on the oral cavity. Understanding the role of the microbiome in treatment-induced tissue toxicity is essential for future therapeutic interventions. Further research is needed to explore the changes in head and neck microbiome, especially outside the oral cavity, and its impact on treatment effectiveness.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Yun Xu, Hewei Peng, Qiaojuan Guo, Lanyan Guo, Xiane Peng, Shaojun Lin
Summary: This study investigated the impact of percutaneous endoscopic gastrostomy (PEG) on the quality of life (QoL) of patients with locally advanced nasopharyngeal carcinoma (LA-NPC) without progression. The study found that PEG did not have a detrimental effect on the long-term QoL of these patients.
Article
Oncology
Cathalijne C. B. Post, Stephanie M. de Boer, Melanie E. Powell, Linda Mileshkin, Dionyssios Katsaros, Paul Bessette, Christine Haie-Meder, Nelleke P. B. Ottevanger, Jonathan A. Ledermann, Pearly Khaw, Romerai D'Amico, Anthony Fyles, Marie Helene Baron, Henry C. Kitchener, Hans W. Nijman, Ludy C. H. W. Lutgens, Susan Brooks, Ina M. Jurgenliemk-Schulz, Amanda Feeney, Geraldine Goss, Roldano Fossati, Prafull Ghatage, Alexandra Leary, Viet Do, Andrea A. Lissoni, Mary McCormack, Remi A. Nout, Karen W. Verhoeven-Adema, Vincent T. H. B. M. Smit, Hein Putter, Carien L. Creutzberg
Summary: The study compared long-term adverse events and health-related quality of life between chemoradiation therapy and radiation therapy alone in high-risk endometrial cancer patients. Results showed that the chemoradiation therapy group had more patients with grade ≥ 2 adverse events at 5 years, and persistent sensory neuropathy toxicity led to more patients reporting significant tingling or numbness in HRQOL. Physical and role functioning impairments were seen up to 3 years in the chemoradiation therapy group.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2021)
Article
Health Care Sciences & Services
Salvatore Crimi, Salvatore Battaglia, Claudia Maugeri, Sergio Mirabella, Luca Fiorillo, Gabriele Cervino, Alberto Bianchi
Summary: The objective of this study was to investigate whether age is a significant risk factor for spinal nerve injury following selective neck dissection (SND) in patients with head and neck cancer. A retrospective cohort study was conducted and found that older patients are more likely to experience spinal nerve injury after SND than younger patients. These findings may help in the development of strategies to prevent spinal nerve injury in older patients undergoing SND for head and neck cancer.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Surgery
Samuel Frey, Bastien Perrot, Cecile Caillard, Maelle Le Bras, Maxime Gerard, Claire Blanchard, Bertrand Cariou, Matthieu Wargny, Eric Mirallie
Summary: This study evaluated the long-term impact of parathyroidectomy (PTX) on quality of life (QoL) in patients with primary hyperparathyroidism (PHPT). The results showed that QoL significantly improved at 1 year and was sustained for at least 3 years after PTX. Additionally, while the physical component score normalized after 3 years, the mental component score remained lower than the reference population.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Letter
Otorhinolaryngology
Kristin Stevens, Amy Anne Lassig
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY
(2020)
Article
Medicine, General & Internal
Akihiko Saitoh, Kiyomi Sato, Yoko Magara, Kakuei Osaki, Kiyoko Narita, Kumiko Shioiri, Karen E. Fowler, David Ratz, Sanjay Saint
JOURNAL OF HOSPITAL MEDICINE
(2020)
Article
Public, Environmental & Occupational Health
Karen E. Fowler, Sarah L. Krein, David Ratz, Debbie Zawol, Sanjay Saint
Summary: The study found that a quality improvement intervention successfully reduced urethral catheter use in the long term at a Veterans Affairs hospital, with continued decrease in utilization and unchanged appropriateness of use.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
M. Todd Greene, Sarah L. Krein, Anita Huis, Marlies Hulscher, Hugo Sax, Fumie Sakamoto, Tomoko Sakihama, Yasuharu Tokuda, Karen E. Fowler, Sanjay Saint
Summary: The study assessed the regular use of evidence-based practices in acute care hospitals across the US, Netherlands, Switzerland, and Japan. Most hospitals adopted recommended practices, but there were opportunities for reducing hospital-acquired infection risks in all four countries. Some prevention practices were used less frequently in Swiss and Japanese hospitals, and surveillance systems were lacking in Dutch, Swiss, and Japanese hospitals.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Infectious Diseases
Kohta Katayama, Jennifer Meddings, Sanjay Saint, Karen E. Fowler, David Ratz, Yasuaki Tagashira, Yumi Kawamura, Tatsuya Fujikawa, Sho Nishiguchi, Naomi Kayauchi, Nobumasa Takagaki, Yasuharu Tokuda, Akira Kuriyama
Summary: This study investigated the prevalence and appropriateness of indwelling urinary catheters, and the incidence of catheter-associated urinary tract infection (CAUTI) in non-intensive care unit (non-ICU) wards in Japanese hospitals. The study found that the mean prevalence of catheter use was 13%, the mean incidence of CAUTI was 9.86 per 1000 catheter-days, and approximately 66% of the catheter days had appropriate indications for use.
BMC INFECTIOUS DISEASES
(2022)
Article
Surgery
Anna C. Wilson, Walter N. Jungbauer, Fareeda T. Hussain, Bruce R. Lindgren, Amy Anne D. Lassig
Summary: Thermography is a diagnostic method that accurately shows physiological and/or pathological temperature changes in the skin. This study evaluated the factors influencing cutaneous tissue perfusion as measured by thermography, including gender, race, and smoking. The results showed significant effects of gender on thermographic temperature at different anatomical sites, while race did not have a significant difference. Smoking did not show a significant difference in thermographic temperatures, but there was a trend of decreased perfusion in smokers and e-cigarette users compared to non-smokers.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Pariyamon Thaprawat, Michael Todd Greene, Sanjay Saint, Nongyao Kasatpibal, Karen E. Fowler, Anucha Apisarnthanarak
Summary: This study assessed infection prevention practices in Thai hospitals for CAUTI, CLABSI, and VAP and compared them to previous results. The findings showed improvement in some prevention practices, but many areas still need improvement. COVID-19 has presented challenges such as staff shortages and financial hardships. The study emphasizes the need for national strategic support to prevent infections and promote healthcare worker well-being during the pandemic.
AMERICAN JOURNAL OF INFECTION CONTROL
(2022)
Article
Health Care Sciences & Services
Richard J. J. Schildhouse, Ashwin Gupta, M. Todd Greene, Karen E. E. Fowler, David Ratz, Mark S. S. Hausman, Sanjay Saint
Summary: Based on a national survey conducted in the US, this study compares the impact of resource shortages and response to the COVID-19 pandemic between Veterans Affairs (VA) and non-federal hospitals. The results show that VA hospitals had advantages in expanding bed capacity, retaining staff, mitigating supply shortages, and avoiding financial hardship compared to non-federal hospitals. The findings suggest that non-federal hospitals can learn from the VA's structure to better prepare for future system shocks.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Sanjay Saint, M. Todd Greene, Sarah L. L. Krein, Karen E. E. Fowler, Kathleen A. A. Linder, David Ratz, Jennifer Meddings
Summary: This study aimed to investigate the changes in device-associated infection prevention practices during the COVID-19 pandemic. Data collected mid-pandemic were used to assess the use of several infection prevention practices and compare them with historical data. The results showed that the use of preventive practices for CLABSI and VAE continued to increase or plateau, while the use of preventive practices for CAUTI decreased.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Heather M. Gilmartin, Sanjay Saint, David Ratz, Kristin Chrouser, Karen E. Fowler, M. Todd Greene
Summary: This study surveyed infection preventionists' perceptions of hospital leadership support for infection prevention and control programs during the COVID-19 pandemic, as well as their relationships with burnout, psychological safety, and safety climate. The results showed an association between strong hospital leadership support and lower burnout, higher perceptions of psychological safety, and a better safety climate. These findings contribute to enhancing the well-being of infection preventionists and improving the quality and safety of patient care.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Shipra Saini, Namita Bindal, Brajesh Kumar Kaushik
Summary: Using first-principle calculations, the authors observe variations in magnetic anisotropy energy and other magnetic properties for transition metal (TM) doped bismuth monolayer. The Mn-doped bismuthene exhibits half-metallicity with higher magnetic moment and magnetic anisotropy energy compared to Fe-doped and Ti-doped systems. The half-metal Mn-Bi can induce half-metallicity in CrI3 through charge transfer, making it the most favorable doped system for spintronic device development in Mn-Bi/CrI3 van der Waals heterostructure.
IEEE OPEN JOURNAL OF NANOTECHNOLOGY
(2023)
Article
Medicine, General & Internal
Ashwin Gupta, Martha Quinn, Sanjay Saint, Richard Lewis, Karen E. Fowler, Suzanne Winter, Vineet Chopra
Summary: This study investigated the diagnostic thinking process of hospital medicine physicians when evaluating patients, using a case-based simulation. The results showed significant heterogeneity in both differential diagnoses and clinical reasoning among the participants. Structured approaches and debiasing strategies were found to be helpful in promoting diagnostic accuracy.
Article
Medicine, General & Internal
Valerie M. Vaughn, Sanjay Saint, M. Todd Greene, David Ratz, Karen E. Fowler, Payal K. Patel, Sarah L. Krein
Article
Medicine, General & Internal
Sanjay Saint, Sarah L. Krein, Karen E. Fowler, John Colozzi, David Ratz, Erica Lescinskas, Kristin Chrouser, Barbara W. Trautner
JOURNAL OF HOSPITAL MEDICINE
(2020)
Meeting Abstract
Urology & Nephrology
Kristin Chrouser, Ted Skolarus, Karen Fowler, Jason Mann, Steven Burstein, Jennifer Meddings
NEUROUROLOGY AND URODYNAMICS
(2020)
