Journal
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
Volume 138, Issue 6, Pages 762-767Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1016/j.otohns.2008.02.022
Keywords
-
Categories
Ask authors/readers for more resources
OBJECTIVES: To determine if tranexamic acid could reduce the drainage duration after head and neck procedures. STUDY DESIGN: Prospective, randomized, controlled trial. METHODS: Patients who underwent head and neck operations were included. The study group was treated with tranexamic acid during the perioperative period whereas the control group received normal saline solution. Blood samples were also collected. RESULTS: The study and control groups consisted of 26 and 29 patients, respectively. Although there was a significant difference in the drainage amount between the two groups, (49.7 vs 88.8 mL, P = 0.041), no significant difference could be found in the drainage duration between the two groups (2.69 vs 3.07 days, P = 0.146). There was also no significant difference in the coagulation profiles between the two groups. CONCLUSION: We did not find a meaningful effect in reducing the drainage duration after head and neck procedures with the use of prophylactic tranexamic acid. (C) 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available