Article
Multidisciplinary Sciences
Antonio Naranjo, Amparo Molina, Adrian Quevedo, Francisco J. Rubino, Fernando Sanchez-Alonso, Carlos Rodriguez-Lozano, Soledad Ojeda
Summary: Long-term adherence to antiosteoporosis medication (AOM) in patients with hip fracture seen at a fracture liaison service (FLS) is suboptimal, although a high proportion maintains good medication coverage during treatment.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Antonio Naranjo, Amparo Molina, Adrian Quevedo, Francisco J. Rubino, Fernando Sanchez-Alonso, Carlos Rodriguez-Lozano, Soledad Ojeda
Summary: The study analyzed the long-term persistence of treatment in fracture liaison service (FLS) and found that most patients started treatment within five years, although the persistence rate decreased over time.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Orthopedics
Ioannis I. Daskalakis, Evangelos I. Kritsotakis, Apostolos H. Karantanas, Georgios M. Kontakis, Johannes D. Bastian, Theodoros H. Tosounidis
Summary: This study aimed to investigate the outcomes of applying a surgeon-led AO Foundation algorithm to hip fracture patients. The results showed that the in-hospital initiation of anti-osteoporotic treatment using this algorithm led to improved medication persistence and decreased incidence of secondary osteoporotic fractures.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Review
Pharmacology & Pharmacy
Holly Tibble, Mary Flook, Aziz Sheikh, Athanasios Tsanas, Rob Horne, Bernard Vrijens, Sabina De Geest, Helen R. Stagg
Summary: Medication non-adherence can lead to increased morbidity, mortality, and side effects, while reducing effectiveness. Methodological issues exist in measuring and reporting adherence for asthma and TB, with variations between and within diseases. The communicable nature of TB has made dose-by-dose monitoring a recommended treatment standard.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2021)
Article
Endocrinology & Metabolism
M. K. Skjodt, M. T. Ernst, S. Khalid, C. Libanati, C. Cooper, A. Delmestri, K. H. Rubin, M. K. Javaid, D. Martinez-Laguna, E. Toth, D. Prieto-Alhambra, B. Abrahamsen
Summary: This study reveals a significant and persistent treatment gap in anti-osteoporosis treatment in patients aged 50 years and older who suffered major osteoporotic fractures in Denmark between 2005 and 2014, even with the inclusion of hospital-administered treatments. Strengthened post-fracture care organization and secondary fracture prevention are urgently needed.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Allergy
Oliver Pfaar, Philippe Devillier, Jochen Schmitt, Pascal Demoly, Ole Hilberg, Lawrence DuBuske, Nicole Hass, Ted Klok, Caroline Beutner
Summary: The 'Adherence and Persistence in AIT (APAIT)' checklist has been developed as a guide for reporting, designing, and interpreting retrospective studies on adherence or persistence to allergen immunotherapy (AIT). The checklist highlights the importance of transparency in reporting and identifies potential sources of bias in these studies.
Article
Ethnic Studies
Orla C. Sheehan, Mandip S. Dhamoon, Janet Prvu Bettger, Jin Huang, Chelsea Liu, J. David Rhodes, Olivio J. Clay, David L. Roth
Summary: This study investigated the effects of race and sex on medication adherence in stroke survivors with family caregivers. Results showed that despite similar prescription rates at discharge, Black stroke survivors were more likely to discontinue antithrombotic medications compared to White patients.
ETHNICITY & HEALTH
(2022)
Review
Allergy
Caroline Beutner, Jochen Schmitt, Margitta Worm, Martin Wagenmann, Christian Albus, Timo Buhl
Summary: Allergen immunotherapy (AIT) involves gradually increasing the dose of allergen extract until immunologic tolerance is achieved. Adherence to AIT is crucial for long-term success, but measuring adherence and persistence rates has been inconsistent. The development of standardized tools and parameters for measuring adherence in AIT is necessary. Additionally, exploring methods from adherence research in other chronic diseases could help improve outcomes in AIT.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2023)
Article
Endocrinology & Metabolism
Zaineb Mohsin, M. Kassim Javaid, Antony Johansen
Summary: Hip fractures are strong risk factors for further fractures. However, there is significant variability in the prescription of anti-osteoporosis medication, particularly injectables, among different hospitals in England and Wales. Further investigation is needed to understand and address this variability.
ARCHIVES OF OSTEOPOROSIS
(2023)
Article
Clinical Neurology
Sang Min Lee, Hyeon-Kyoung Cheong, In-Hwan Oh, Minha Hong
Summary: This study divided adults with ADHD into groups based on their childhood and adulthood diagnosis, and compared characteristics, medication adherence, and persistence. Results showed that treatment in private clinics and initial monotherapy with bupropion were significantly associated with adherence.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Endocrinology & Metabolism
Thomas J. Hjelholt, Soren P. Johnsen, Peter K. Brynningsen, Grethe Andersen, Alma B. Pedersen
Summary: Considerable uncertainty exists regarding the risk factors for recurrent fracture among older patients with hip fracture. This study aimed to investigate the relationship between prefracture stroke history, baseline mobility, and the risk of recurrent hip fracture. The findings showed that stroke history was associated with the cumulative incidence of recurrent hip fracture within one year, but its association varied depending on the baseline mobility of the patients.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Review
Medicine, General & Internal
Colum Downey, Stephen Flannery, Ben Murphy, Tiarnan Daly, Sarah Conway, Mohammed Gaffar, Peter Dawson, Patrick O'Kelly, Denis Collins, Paddy Kenny, Tom McCarthy, James Cashman, Conor Shortt, Brendan O'Daly, Conor Hurson, John Quinlan
Summary: In 2019, 8.7% of fragility hip fractures in 6 Irish teaching hospitals were secondary hip fractures, with 46% occurring within years 1 to 3. Forty-eight percent of patients were started on bone protection medications following their second hip fracture. The study highlights the importance of implementing Fracture Liaison Services in Ireland to prevent secondary fractures.
IRISH JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Endocrinology & Metabolism
Chor-Wing Sing, Tzu-Chieh Lin, Sharon Bartholomew, J. Simon Bell, Corina Bennett, Kebede Beyene, Pauline Bosco-Levy, Brian D. Bradbury, Amy Hai Yan Chan, Manju Chandran, Cyrus Cooper, Maria de Ridder, Caroline Y. Doyon, Cecile Droz-Perroteau, Ganga Ganesan, Sirpa Hartikainen, Jenni Ilomaki, Han Eol Jeong, Douglas P. Kiel, Kiyoshi Kubota, Edward Chia-Cheng Lai, Jeff L. Lange, E. Michael Lewiecki, Julian Lin, Jiannong Liu, Joe Maskell, Mirhelen Mendes de Abreu, James O'Kelly, Nobuhiro Ooba, Alma B. Pedersen, Albert Prats-Uribe, Daniel Prieto-Alhambra, Simon Xiwen Qin, Ju-Young Shin, Henrik T. Sorensen, Kelvin Bryan Tan, Tracy Thomas, Anna-Maija Tolppanen, Katia M. C. Verhamme, Grace Hsin-Min Wang, Sawaeng Watcharathanakij, Stephen J. Wood, Ching-Lung Cheung, Ian C. K. Wong
Summary: In this international study, the researchers analyzed the incidence of hip fractures, post-fracture treatment, and all-cause mortality following hip fractures across different countries and regions. They used patient-level healthcare data from 19 countries and identified 4,115,046 hip fractures from 2005 to 2018. The study revealed variations in the global epidemiology of hip fractures and post-fracture outcomes, highlighting the need for interventions to reduce the burden of osteoporotic fractures.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Geriatrics & Gerontology
Banne Nemeth, Marleen van der Kaaij, Rob Nelissen, Jan-Kees van Wijnen, Katja Drost, Gerard Jan Blauw
Summary: The introduction of the WOLK hip airbag in long-term care facilities for older patients significantly reduced the incidence of hip and pelvic fractures by almost half.
Article
Medicine, General & Internal
Aseel Awad Alsaidan, Omar Awad Alsaidan, Tauqeer Hussain Mallhi, Yusra Habib Khan, Abdulaziz Ibrahim Alzarea, Abdullah Salah Alanazi
Summary: This study aimed to determine the adherence pattern and factors linked with nonadherence among diabetic patients using insulin in Al-Jouf region of Saudi Arabia. The majority of patients forget to inject insulin, primarily as a result of travel. By identifying potential obstacles faced by patients, these findings direct health authorities to design and implement initiatives to increase insulin adherence among patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Jun Ho Yun, Heun-Sik Lee, Ho-Yeong Yu, Yeon-Jung Kim, Hyun Jeong Jeon, Taekeun Oh, Bong-Jo Kim, Hyung Jin Choi, Jeong-Min Kim
Article
Medicine, General & Internal
Eu Jeong Ku, Ji-In Park, Hyun Jeong Jeon, Taekeun Oh, Hyung Jin Choi
INTERNAL MEDICINE JOURNAL
(2020)
Article
Health Care Sciences & Services
Meelim Kim, Youngin Kim, Yoonjeong Go, Seokoh Lee, Myeongjin Na, Younghee Lee, Sungwon Choi, Hyung Jin Choi
JMIR MHEALTH AND UHEALTH
(2020)
Letter
Medicine, General & Internal
Eu Jeong Ku, Hyung Jin Choi
INTERNAL MEDICINE JOURNAL
(2021)
Article
Medicine, Research & Experimental
Min Sun Kim, Jang Ho Ahn, Ji Eun Mo, Ha Young Song, Deokhyeon Cheon, Seong Ho Yoo, Hyung Jin Choi
Summary: Fresh samples outperformed cadaver samples in terms of clearing efficiency, artifacts, and DAPI staining efficiency, but had similar GFAP staining efficiency. The penetration depth and DAPI staining in fresh samples improved with longer incubation periods. 4DS-C was the best method with the deepest penetration.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2021)
Review
Endocrinology & Metabolism
Meelim Kim, Hyung Jin Choi
Summary: In recent years, digital technologies have advanced rapidly and are being used to address medical issues, particularly in monitoring and managing physical and mental health. Digital therapeutics (DTx) are seen as a powerful and easily accessible treatment modality for obesity and eating behavior problems. To enhance the effectiveness of DTx, collaboration among stakeholders such as health professionals, patients, guardians, industry partners, and policy-makers is crucial.
ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Health Care Sciences & Services
Meelim Kim, Jaeyeong Yang, Woo-Young Ahn, Hyung Jin Choi
Summary: This study used a machine learning approach to investigate the performance of multivariate phenotypes in predicting engagement rate and health outcomes of digital cognitive behavioral therapy, revealing the impact of various psychological constructs on the effectiveness of digital interventions. The findings suggest the potential for developing advanced prevention and personalized digital therapeutics.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Letter
Endocrinology & Metabolism
Hyung Jin Choi
JOURNAL OF OBESITY & METABOLIC SYNDROME
(2021)
Article
Biotechnology & Applied Microbiology
Chang Yeon Kim, Jang Ho Ahn, Do Hyun Han, Cherl NamKoong, Hyung Jin Choi
Summary: The hypothalamic arcuate nucleus (ARC) is crucial in regulating feeding and energy homeostasis. A comparative proteomic analysis found 178 differentially expressed proteins (DEPs) in the ARC induced by high-fat diet, suggesting potential novel treatment targets.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Multidisciplinary Sciences
Young Hyun Yun, Dong Hyun Jo, Su Kyoung Jeon, Hyeok Yi Kwon, Yu Mi Jeon, Dong Hoon Shin, Hyung Jin Choi
Summary: The study showed that despite modifications to the anatomy education schedule at Seoul National University College of Medicine due to the COVID-19 pandemic, there were no confirmed cases of COVID-19 among students, faculty, and staff during laboratory sessions. Most students experienced a significant decrease in scores on written and practical examinations in 2020 compared to 2019, except for the trunk session that utilized a virtual anatomy application, which saw an improvement in practical examination scores. This highlights the importance of developing appropriate education programs to adapt to pandemic restrictions.
Correction
Multidisciplinary Sciences
Seul Ki Kim, Le Trung Tran, Cherl NamKoong, Hyung Jin Choi, Hye Jin Chun, Yong-ho Lee, MyungHyun Cheon, ChiHye Chung, Junmo Hwang, Hyun-Ho Lim, Dong Min Shin, Yun-Hee Choi, Ki Woo Kim
NATURE COMMUNICATIONS
(2023)
Article
Clinical Neurology
A. Ram Hong, Jung Hee Kim, Seung Shin Park, Sung Hye Kong, Hyung Jin Choi, Yong Hwy Kim, Chan Soo Shin
Summary: This study aimed to investigate the factors contributing to postoperative weight gain in patients with Craniopharyngiomas (CP). The results showed that CP patients experienced greater postoperative weight gain compared to patients with non-functioning pituitary adenoma (NFPA). The study suggests that hypothalamic damage itself and steroid replacement therapy may contribute to the postoperative weight gain in CP patients.
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
(2022)
Article
Endocrinology & Metabolism
Jae Hyun Bae, Hyung Jin Choi, Kang Ik Kevin Cho, Lee Kyung Kim, Jun Soo Kwon, Young Min Cho
DIABETES & METABOLISM JOURNAL
(2020)
Article
Health Care Sciences & Services
Youjin Hwang, Hyung Jun Kim, Hyung Jin Choi, Joonhwan Lee
JOURNAL OF MEDICAL INTERNET RESEARCH
(2020)
Review
Endocrinology & Metabolism
Young Hee Lee, Meelim Kim, Miwoo Lee, Dongju Shin, Dong-Soo Ha, Joon Seok Park, You Bin Kim, Hyung Jin Choi
JOURNAL OF OBESITY & METABOLIC SYNDROME
(2019)