Article
Multidisciplinary Sciences
Ji Min Park, Chen-Zou Mau, Yang-Ching Chen, Yen-Hao Su, Hsin-An Chen, Shih-Yi Huang, Jung-Su Chang, Ching-Feng Chiu
Summary: High levels of serum ferritin (SF) may indicate risk of pancreatic cancer as a new tumor marker for diagnosis, while genes related to iron homeostasis and ferroptosis could contribute to pancreatic cancer risk and prognosis.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Hongzhen Du, Tianfeng Zhang, Xuning Lu, Meicui Chen, Xiaoling Li, Zengning Li
Summary: This study aimed to summarize previous findings on the relationship between glycemic index (GI) or glycemic load (GL) and lung cancer risk. The results of meta-analysis showed a positive association between GI and lung cancer risk, while no associations were found between GL and lung cancer risk.
Article
Genetics & Heredity
Ainur Seisenova, Asset Daniyarov, Askhat Molkenov, Aigul Sharip, Andrei Zinovyev, Ulykbek Kairov
Summary: The study utilized ICA to analyze publicly available esophageal cancer data to identify and comprehensively analyze reproducible signaling pathways and molecular signatures in this cancer type. The results may uncover potential biomarkers of esophageal carcinogenesis and help predict early tumor development.
FRONTIERS IN GENETICS
(2021)
Review
Food Science & Technology
Pablo Hernandez-Alonso, Hatim Boughanem, Silvia Canudas, Nerea Becerra-Tomas, Maria Fernandez de la Puente, Nancy Babio, Manuel Macias-Gonzalez, Jordi Salas-Salvado
Summary: This systematic review and meta-analysis revealed an inverse association between circulating vitamin D levels and colorectal cancer risk.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Oncology
Lingzhi Yuan, Peijun Shen, Shaopeng Zheng, Dongwen Wu, Xinmeng Li, Ting Cai, Yao Yao, Yunhe Song, Fen Wang
Summary: This study conducted a research in a high-incidence area of esophageal cancer in China and found that eating too fast, drinking alcohol, consuming hot drinks, smoking, and overeating are the main risk factors for esophageal cancer. It is recommended to improve the management and treatment outcomes of esophageal cancer by changing unhealthy lifestyle habits, especially reducing excessive eating and eating too fast.
FRONTIERS IN ONCOLOGY
(2023)
Article
Environmental Sciences
Jinyoung Moon, HyeKyoung Yoo
Summary: This study conducted a comprehensive review and meta-analysis on the possible causal association between residential radon exposure and leukemia. Various types of studies were included, showing a correlation between radon exposure and leukemia, with different responses among age groups and leukemia types. Further large-scale studies are needed for more accurate conclusions.
ENVIRONMENTAL RESEARCH
(2021)
Review
Medicine, General & Internal
Fengdie He, Yuting Sha, Baohua Wang
Summary: The meta-analysis study showed a significant correlation between alcohol consumption and the risks of liver, esophageal squamous cell carcinoma (ESCC), and gastric cancers in China mainland. The volume of alcohol consumed, years of drinking, age of starting drinking, and drinking status were significant factors for these risks. Geographical region was identified as a source of heterogeneity.
Review
Medicine, General & Internal
Lei Lei, Xiang-Yu Zhou, Li-Li Xiang, Jie Xiang, Xu Li
Summary: There may be a potential association between psychosocial factors and esophageal cancer risk, with psychological trauma and depression increasing the risk, while good interpersonal relationships and outgoing personalities may lower the risk of esophageal cancer.
Article
Endocrinology & Metabolism
Po-Wei Chen, Hsiao-Yuan Su, Yu-Kang Tu, Chih-Hsing Wu, Jih- Yeh, Li-Yu Chen, Carol Chiung-Hui Peng, Ching-Hui Loh, Huei-Kai Huang, Shu-Man Lin
Summary: Bisphosphonate use is associated with a lower risk of diabetes, although the results from randomized controlled trials are inconsistent. Further studies are needed to determine causality.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Public, Environmental & Occupational Health
Pang Yao, Christiana Kartsonaki, Julia Butt, Rima Jeske, Catherine de Martel, Martyn Plummer, Yu Guo, Sarah Clark, Robin G. Walters, Yiping Chen, Daniel Avery, Jun Lv, Canqing Yu, Hao Wang, Michael Hill, Richard Peto, Liming Li, Tim Waterboer, Zhengming Chen, Iona Y. Millwood, Ling Yang
Summary: This study found that Helicobacter pylori infection is associated with the risk of non-cardia gastric cancer (NCGC) and cardia gastric cancer (CGC). There is uncertainty about the associations between sero-positivity to different H. pylori antigens and the risk of NCGC and CGC in different populations.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Sara Rodriguez-Martin, Diana Barreira-Hernandez, Ramon Mazzucchelli, Miguel Gil, Alberto Garcia-Lledo, Laura Izquierdo-Esteban, Ana Perez-Gomez, Antonio Rodriguez-Miguel, Francisco J. De Abajo
Summary: In this case-control study, the use of oral bisphosphonates was found to specifically increase the risk of cardioembolic ischemic stroke, but had little effect on non-cardioembolic stroke. The duration of bisphosphonate use and the interaction with calcium supplements and anticoagulants were also observed to play a role. These findings have important implications for clinical practice.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Oncology
Chang Kyun Choi, Jungho Yang, Sun-Seog Kweon, Sang-Hee Cho, Hye-Yeon Kim, Eun Myung, Min-Ho Shin
Summary: In Eastern Asians, ALDH2 rs671 polymorphisms are associated with esophageal cancer, which may be linked to acetaldehyde accumulation. The study found that in men, the risk of esophageal cancer was higher with GA and AA genotypes, while in women, the risk was higher with GA and AA genotypes as well. Additionally, in men, the association between ALDH2 polymorphisms and esophageal cancer was influenced by alcohol consumption.
Article
Genetics & Heredity
Carolina Mathias, Anelis Maria Marin, Ana Flavia Kohler, Heloisa Bruna Soligo Sanchuki, Natalie Sukow, Marcia Holsbach Beltrame, Suelen Cristina Soares Baal, Ana Paula Martins Sebastiao, Enilze Maria de Souza Fonseca Ribeiro, Daniela Fiori Gradia, Mateus Nobrega Aoki, Jaqueline Carvalho de Oliveira
Summary: Long noncoding RNAs (lncRNAs) are a type of RNA molecule that do not code for proteins and have a regulatory role. This study identified lncRNA-SNPs with a potential biological role in the development of breast cancer (BC) in the Brazilian population. Certain SNPs were found to be associated with BC development and patient characteristics.
Article
Multidisciplinary Sciences
Guocan Yu, Wenfeng Yu, Xudong Xu, Bo Ye, Liwei Yao
Summary: This study aims to evaluate the efficacy and safety of immunotherapy for resectable esophageal cancer as neoadjuvant treatment, providing reliable evidence for clinicians and patients to formulate the best pre-surgical treatment plan.
Review
Medicine, General & Internal
Minghao Li, Muyan Zhong, Chengnong Guan
Summary: In general, there is no significant association between the use of BPs and the risk of lung cancer, but the use of alendronate may increase the risk of lung cancer. Further studies are needed to confirm these findings.