Article
Endocrinology & Metabolism
E. McCloskey, J. Rathi, S. Heijmans, M. Blagden, B. Cortet, E. Czerwinski, P. Hadji, J. Payer, K. Palmer, R. Stad, J. O'Kelly, S. Papapoulos
Summary: This study conducted in 8 European countries revealed a significant treatment gap in osteoporosis-related fracture risk management for elderly women in primary care, mainly due to the lack of osteoporosis diagnosis.
OSTEOPOROSIS INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Patrick Pflueger, Felix N. Harder, Karoline Mueller, Lukas Willinger, Peter Biberthaler, Moritz Croenlein
Summary: Trimalleolar ankle fractures predominantly affect younger men and older women, with postmenopausal women having lower bone mineral density and a higher risk of fractures. This study aimed to analyze the association between patient characteristics and cortical bone thickness of the distal tibia in trimalleolar ankle fractures. The results showed that older age and female sex were associated with reduced cortical bone thickness and an increased risk of subsequent osteoporotic fractures.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Benjamin Tze Keong Ding, Hai Fon Lim, Fadzleen Johari, Remesh Kunnasegaran
Summary: This study evaluates the efficacy of an Orthopaedic Surgeon Led Osteoporosis Model of Care (OSLO-MoC) in improving the care of patients with primary osteoporotic fractures. The study shows that the OSLO-MOC is effective in improving medication compliance and reducing secondary fractures in patients.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Orthopedics
Ludwig Oberkircher, Julia Lenz, Benjamin Buecking, Daphne Eschbach, Rene Aigner, Christopher Bliemel, Carsten Schoeneberg, Steffen Ruchholtz, Juliana Hack
Summary: This study aimed to describe specific characteristics of patients with pelvic fragility fractures and evaluate factors influencing treatment decisions. Results showed that fracture type, mobility level, and pain level were key factors influencing the decision for surgical treatment. Patients with B2 fractures benefited in terms of mobility level with surgical treatment at discharge.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Endocrinology & Metabolism
Salvador Israel Macias-Hernandez, Miriam Macarena Degollado-Rodriguez, Horacio Maldonado-Sanchez, Andrea Olascoaga-Gomez de Leon, Roberto Coronado-Zarco, Tania Ines Nava-Bringas, Esperanza Ramirez-Perez, Eva Cruz-Medina, Rolando Espinosa-Morales, Juan Daniel Morones-Alba
Summary: This study highlights the diagnostic and therapeutic gap for osteoporosis in patients with fragility fractures in Mexico, showing a higher rate of failure to diagnose and treat osteoporosis compared to other countries. Measures should be taken to reduce this gap and improve care for these patients.
ARCHIVES OF OSTEOPOROSIS
(2021)
Article
Endocrinology & Metabolism
Hiroki Iida, Yoshihito Sakai, Taisuke Seki, Tsuyoshi Watanabe, Norimitsu Wakao, Hiroki Matsui, Shiro Imagama
Summary: The study investigates the impact of bisphosphonate (BP) on mortality post osteoporotic vertebral fracture (OVF), and finds that BP medication is significantly associated with reduced all-cause mortality after OVF.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Daniel Martinez-Laguna, Cristina Carbonell, Jose-Carlos Bastida, Milagros Gonzalez, Rafael M. Mico-Perez, Francisco Vargas, Monica Balcells-Oliver, Laura Canals
Summary: In Spanish primary care, the prevalence of fragility fractures is high, especially in women. A significant number of subjects with a fragility fracture lack an osteoporosis diagnosis and are not receiving medication for osteoporosis. There is a need to improve the management of fragility fractures in this population.
ARCHIVES OF OSTEOPOROSIS
(2022)
Article
Endocrinology & Metabolism
Eugene McCloskey, Jeetandera Rathi, Stephane Heijmans, Mark Blagden, Bernard Cortet, Edward Czerwinski, Peyman Hadji, Juraj Payer, Kerry Palmer, Robert Stad, James O'Kelly, Socrates Papapoulos
Summary: This study examines whether elderly women at risk for fractures receive primary care treatment to prevent fracture. The findings show that women at risk are often not identified across Europe, and less than half of them receive appropriate treatment. Furthermore, women diagnosed with osteoporosis are more likely to receive treatment.
ARCHIVES OF OSTEOPOROSIS
(2022)
Article
Geriatrics & Gerontology
Isabel Geiger, Christian Kammerlander, Christine Hoefer, Ruth Volland, Joerg Trinemeier, Martina Henschelchen, Thomas Friess, Wolfgang Boecker, Leonie Sundmacher
Summary: The study aims to evaluate whether a coordinated care programme can reduce the secondary fracture rate for patients with fragility hip fractures in Germany, by implementing systematic diagnostics, falls prevention programmes, and guideline-adherent interventions based on the Fracture Liaison Services model. The findings will shed light on potential barriers to FLS implementation in the German healthcare system.
Article
Endocrinology & Metabolism
Tomoko Fujii, Takahiro Mori, Jun Komiyama, Naoaki Kuroda, Nanako Tamiya
Summary: In an analysis of claims data from a city in Japan, it was found that male patients and patients with dementia were less likely to receive osteoporosis pharmacotherapy after hip fracture. However, the treatment initiation rate has improved between 2014 and 2017.
ARCHIVES OF OSTEOPOROSIS
(2023)
Article
Endocrinology & Metabolism
U. Tarantino, C. Greggi, V. V. Visconti, I Cariati, R. Bonanni, B. Gasperini, R. Iundusi, E. Gasbarra, P. Tranquilli Leali, M. L. Brandi
Summary: Frailty fractures, especially femoral fractures, place a significant socioeconomic burden on the healthcare system globally. The fracture liaison service (FLS) represents a multidisciplinary approach to post-fracture care for frail patients. The Italian Society of Orthopaedics and Traumatology (SIOT) is working towards accrediting multiple FLS centers throughout Italy.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Maria-Jose Montoya-Garcia, Merce Giner, Rodrigo Marcos, David Garcia-Romero, Francisco-Jesus Olmo-Montes, Ma Jose Miranda, Blanca Hernandez-Cruz, Miguel-Angel Colmenero, Ma Angeles Vazquez-Gamez
Summary: Fragility fractures are a significant public health issue globally, with hip fractures being most prevalent in women aged 80 and above. Older age and recent fractures were identified as independent risk factors for further fracture events. There was a significant excess mortality rate in individuals aged 80 and above with a previous hip fracture.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Geriatrics & Gerontology
Nicholas Fuggle, Nasser Al-Daghri, Olivier Bock, Jaime Branco, Olivier Bruyere, Enrique Casado, Etienne Cavalier, Bernard Cortet, Maarten de Wit, Andrea Giusti, Philippe Halbout, Nicholas C. Harvey, Mickael Hiligsmann, Jean-Marc Kaufman, Andreas Kurth, Stefania Maggi, Radmila Matijevic, Salvatore Minisola, Santiago Palacios, Regis Pierre Radermecker, Friederike Thomasius, Sansin Tuzun, Nicola Veronese, John A. Kanis, Jean-Yves Reginster, Rene Rizzoli, Cyrus Cooper
Summary: Oral bisphosphonates are important in the treatment of osteoporosis, but poor adherence is a problem. New formulations aim to improve tolerance and adherence, potentially leading to better fracture outcomes.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Endocrinology & Metabolism
Zhanna Belaya, Liudmila Rozhinskaya, Ivan Dedov, Oksana Drapkina, Valentin Fadeev, Olga Golounina, Olga Lesnyak, Elizaveta Mamedova, Galina Melnichenko, Alexey Petraikin, Svetlana Rodionova, Irina Skripnikova, Olga Tkacheva, Natalia Toroptsova, Svetlana Yureneva, John A. Kanis
Summary: The key statements of the Russian clinical guidelines on the diagnosis and treatment of osteoporosis have been summarized. These guidelines were developed by key professional associations in Russia and approved by the Ministry of Health. They provide a practical tool for healthcare professionals involved in managing patients with osteoporosis.
OSTEOPOROSIS INTERNATIONAL
(2023)
Review
Endocrinology & Metabolism
Umberto Tarantino, Ida Cariati, Chiara Greggi, Riccardo Iundusi, Elena Gasbarra, Giovanni Iolascon, Andreas Kurth, Kristina E. Akesson, Mary Bouxsein, Paolo Tranquilli Leali, Roberto Civinini, Francesco Falez, Maria Luisa Brandi
Summary: Osteoporotic fractures are a major problem in healthcare systems worldwide. Fragility fractures of the hip have a greater impact on morbidity, mortality, and healthcare costs than other fracture sites. There is a lack of awareness of osteoporosis and most high-risk individuals do not receive adequate treatment.
OSTEOPOROSIS INTERNATIONAL
(2022)
Meeting Abstract
Rheumatology
R. M. Fleischmann, L. Bessette, J. Sparks, S. Hall, M. Jain, A. Kakehasi, Y. Song, S. Meerwein, R. Demasi, J. Suboticki, A. Rubbert-Roth
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Meeting Abstract
Rheumatology
P. Nash, A. Kavanaugh, M. H. Buch, B. Combe, L. Bessette, I. H. Song, T. Shaw, Y. Song, J. Suboticki, R. M. Fleischmann
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Letter
Rheumatology
Louis Bessette, Cassandra D. Kinch
JOURNAL OF RHEUMATOLOGY
(2023)
Article
Health Care Sciences & Services
Susan J. Bartlett, Vivian P. Bykerk, Orit Schieir, Marie-France Valois, Janet E. Pope, Gilles Boire, Carol Hitchon, Glen Hazlewood, Louis Bessette, Edward Keystone, Carter Thorne, Diane Tin, Clifton O. Bingham
Summary: This study investigated the perception of disease activity change in rheumatoid arthritis (RA) patients and physicians, and estimated minimal and meaningful change thresholds. The results showed that the thresholds varied depending on the anchor used. These findings provide guidance for the assessment and decision-making in the management of RA.
QUALITY OF LIFE RESEARCH
(2023)
Article
Rheumatology
Louis Bessette, Mohammad Movahedi, George Reed, Joel M. Kremer, Kevin Kane, Edward Keystone
Summary: This study evaluated the response to a second TNFi or non-TNFi in patients failing their initial TNFi treatment. The results showed that patients with secondary failure were more likely to achieve treatment goals compared to patients with primary failure, regardless of the choice of second treatment.
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
(2023)
Correction
Rheumatology
R. Fleischmann, E. Mysler, L. Bessette
Article
Rheumatology
Walter P. Maksymowych, Robert D. Inman, Louis Bessette, Proton Rahman, Emmanouil Rampakakis, Odalis Asin-Milan, Meagan Rachich, Anne Marilise Marrache, Allen J. Lehman
Summary: A study found that sustained disease activity states, as measured by BASDAI and ASDAS, impact function in axial spondyloarthritis patients. Characteristics predicting sustained low functional impairment were evaluated in this prospective cohort study.
ARTHRITIS RESEARCH & THERAPY
(2023)
Article
Rheumatology
Louis Bessette, Boulos Haraoui, Emmanouil Rampakakis, Joanna Dembowy, Marc-Olivier Trepanier, Janet Pope
Summary: A study compared the effects of a treat-to-target approach and routine care in patients with rheumatoid arthritis and found that treat-to-target approach resulted in faster achievement of therapeutic goals.
ARTHRITIS RESEARCH & THERAPY
(2023)
Meeting Abstract
Medicine, General & Internal
Roy Fleischmann, Louis Bessette, Jeffrey Sparks, Stephen Hall, Manish Jain, Adriana Kakehasi, Yanna Song, Sebastian Meerwein, Ryan DeMasi, Jessica Suboticki, Andrea Rubbert-Roth
SWISS MEDICAL WEEKLY
(2022)
Meeting Abstract
Rheumatology
Peter Nash, Arthur Kavanaugh, Maya Buch, Bernard Combe, Louis Bessette, In-Ho Song, Tim Shaw, Yanna Song, Jessica Suboticki, Roy Fleischmann
JOURNAL OF RHEUMATOLOGY
(2022)
Meeting Abstract
Rheumatology
Viviane Ta, Orit Schieir, Marie-France Valois, Vivian Bykerk, Ines Colmegna, Carol Hitchon, Diane Tin, Carter Thorne, Louis Bessette, Glen Hazlewood, Edward Keystone, Gilles Boire, Janet Pope, Susan Bartlett
JOURNAL OF RHEUMATOLOGY
(2022)
Meeting Abstract
Rheumatology
Susan Bartlett, Orit Schieir, Marie-France Valois, Janet Pope, Glen Hazlewood, Louis Bessette, Gilles Boire, Diane Tin, Carter Thorne, Edward Keystone, Carol Hitchon, Vivian Bykerk
JOURNAL OF RHEUMATOLOGY
(2022)
Meeting Abstract
Endocrinology & Metabolism
Laetitia Michou, Philippe Gamache, Jason R. Guertin, Jean-Eric Tarride, Jacques P. Brown, Sonia Jean
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Rheumatology
Iain B. McInnes, Andrew J. K. Ostor, Philip J. Mease, William Tillett, Xenofon Baraliakos, Kurt de Vlam, Louis Bessette, Ralph Lippe, Anna Maniccia, Dai Feng, Tianming Gao, Patrick Zueger, Christopher Saffore, Koji Kato, In-Ho Song, Atul Deodhar
Summary: The effect of upadacitinib on pain outcomes in patients with active psoriatic arthritis (PsA) or ankylosing spondylitis (AS) was evaluated in three randomized trials. The results showed that a higher proportion of patients receiving upadacitinib achieved significant pain reduction as early as week 2, and these improvements were sustained or increased over one year.
Article
Rheumatology
Viviane Ta, Orit Schieir, Marie-France Valois, Ines Colmegna, Carol Hitchon, Louis Bessette, Glen Hazlewood, Carter Thorne, Janet Pope, Gilles Boire, Diane Tin, Edward C. Keystone, Vivian P. Bykerk, Susan J. Bartlett
Summary: Influenza vaccination coverage in patients with early rheumatoid arthritis (RA) remains below national targets. Discussing vaccine history and medication attitudes at initial clinic visits may enhance vaccine acceptance and uptake.
ACR OPEN RHEUMATOLOGY
(2022)