Review
Clinical Neurology
Eran Beit Ner, Oded Rabau, Saad Dosani, Uri Hazan, Yoram Anekstein, Yossi Smorgick
Summary: Purpose Fatigue stress fractures are a common overuse injury, frequently associated with high load-bearing endurance activities such as running, military training and aerobic exercise, with sacral stress fractures being poorly studied. The literature review revealed a high percentage of sacral stress fractures in professional or collegiate level athletes, with some female athletes having low bone mineral density and history of eating disorders. Conservative treatment is the mainstay of treatment.
EUROPEAN SPINE JOURNAL
(2022)
Review
Environmental Sciences
Varsha Tiwari, Manish Kumar, Abhishek Tiwari, Biswa Mohan Sahoo, Sunil Singh, Suresh Kumar, Renu Saharan
Summary: Coronaviruses display precise adaptation towards respiratory epithelial cells and possess complex anti-viral mechanisms leading to immune system collapse. There are 18 vaccines approved by the WHO and 22 in the third phase of trials. Research on the impact of vaccines on new variants is a current focus.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Plant Sciences
Dilip Ghosh, Sunil Kokane, Brajesh Kumar Savita, Pranav Kumar, Ashwani Kumar Sharma, Ali Ozcan, Amol Kokane, Swadeshmukul Santra
Summary: Huanglongbing (HLB), also known as citrus greening, is a devastating disease of citrus trees caused by Candidatus Liberibacter asiaticus (CLas) bacteria, which are transmitted by psyllid vectors. Current control measures for HLB are ineffective in the long term, leading to difficulty in preventing disease spread. To combat HLB, a multipronged management strategy is necessary, targeting the pathogen, host, and vector.
Article
Orthopedics
Alessandro Aprato, Luigi Branca Vergano, Alessandro Casiraghi, Francesco Liuzza, Umberto Mezzadri, Alberto Balagna, Lorenzo Prandoni, Mohamed Rohayem, Lorenzo Sacchi, Amarildo Smakaj, Mario Arduini, Alessandro Are, Concetto Battiato, Marco Berlusconi, Federico Bove, Stefano Cattaneo, Matteo Cavanna, Federico Chiodini, Matteo Commessatti, Francesco Addevico, Rocco Erasmo, Alberto Ferreli, Claudio Galante, Pietro Domenico Giorgi, Federico Lamponi, Alessandro Moghnie, Michel Oransky, Antonio Panella, Raffaele Pascarella, Federico Santolini, Giuseppe Rosario Schiro, Marco Stella, Kristijan Zoccola, Alessandro Masse
Summary: The Italian Pelvic Trauma Association organized a consensus to determine the best treatment for sacral fractures based on neurological impairment, reaching agreements on various diagnostic methods and treatment indications for different scenarios.
JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Maria Cecilia Mathias-Machado, Renata D'Alpino Peixoto, Camila Motta Venchiarutti Moniz, Alexandre A. Jacome
Summary: Squamous cell carcinoma of the anal canal (SCCA) is a rare neoplasm that is etiologically linked with HPV infection and is more common in immunocompromised patients. Current treatments have limitations in terms of disease recurrence in locally advanced cases and lack of effective systemic therapy. SCCA has specific epigenomic, genomic, and transcriptomic abnormalities compared to other HPV-related malignancies. Therefore, it is important to identify predictive biomarkers and develop personalized treatment approaches.
Article
Radiology, Nuclear Medicine & Medical Imaging
David Dreizin, Elana B. Smith
Summary: CT is a crucial tool in diagnosing and characterizing sacral fractures, which commonly occur in patients with pelvic ring disruption. Understanding the biomechanics and fracture patterns is essential for effective management. Researchers explore various classification systems to improve the diagnosis and communication of sacral fractures.
Review
Critical Care Medicine
Santiago Gutierrez-Gomez, Lauren Wahl, Ronen Blecher, Lukasz Olewnik, Joe Iwanaga, Christopher M. Maulucci, Aaron S. Dumont, R. Shane Tubbs
Summary: Sacral fractures are often underdiagnosed but relatively frequent in the setting of pelvic ring injury, with causes including traumatic insults and osteoporosis. Misdiagnosed and neglected sacral fractures can lead to chronic back pain, spine deformity, and instability, while the wide range of classification systems may hinder communication among clinicians.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Multidisciplinary Sciences
Yoonho Nam, Yangsean Choi, Junghwa Kang, Minkook Seo, Soo Jin Heo, Min Kyoung Lee
Summary: This study assessed the performance of deep learning algorithms in diagnosing nasal bone fractures on radiographs and compared it with that of experienced radiologists. The results showed that the deep learning algorithm performed similarly to radiologists in diagnosing nasal bone fractures.
SCIENTIFIC REPORTS
(2022)
Review
Oncology
Michael P. Rogers, Anthony J. DeSantis, Christopher G. DuCoin
Summary: The diagnosis and management of oligometastatic esophageal adenocarcinoma are complex, and early diagnosis is crucial for prolonging patient survival, but there is currently a lack of definitive treatment options.
Article
Orthopedics
Charles Court, Leonard Chatelain, Barthelemy Valteau, Charlie Bouthors
Summary: In young patients, lumbosacral fractures are primarily caused by high-energy traumas and can lead to life-threatening injuries. The management involves intensive medical care for resuscitation and specialized surgical treatment. An examination of both the spine and pelvis is necessary for any injury in the lumbosacral junction. Surgical fixation is often recommended for unstable fractures with large displacements, and the choice of surgical technique depends on the fracture pattern and surgeon's experience. Close cooperation between pelvic surgeons and spine surgeons is necessary for effective management.
EFORT OPEN REVIEWS
(2023)
Article
Multidisciplinary Sciences
Masaki Tatsumura, Fumihiko Eto, Katsuya Nagashima, Shun Okuwaki, Hisanori Gamada, Sho Iwabuchi, Takeshi Ogawa, Takeo Mammoto, Atsushi Hirano, Masashi Yamazaki
Summary: This study analyzed sacral alar fatigue fractures in adolescent athletes and found differences compared to children and adults. The average age of patients was 14.5 years, with basketball being the most common sports discipline. Diagnosis usually took around 13.2 days.
SCIENTIFIC REPORTS
(2021)
Review
Cardiac & Cardiovascular Systems
Maria Monteagudo-Vela, Alexander Tindale, Emilio Monguio-Santin, Guillermo Reyes-Copa, Vasileios Panoulas
Summary: Right heart failure is a clinical syndrome resulting from right ventricular dysfunction, characterized by signs and symptoms of heart failure. It can be caused by pressure overload, volume overload, or a decrease in contractility. Diagnosis is based on clinical assessment, echocardiographic, laboratory, and hemodynamic parameters, as well as clinical risk assessment. Treatment options include medical management, mechanical assist devices, and transplantation. Attention should be given to special circumstances like left ventricular assist device implantation. New therapies, both pharmacological and device centered, are being developed for the future. Immediate diagnosis, management, and a protocolized approach to weaning are important for successfully managing right ventricular failure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Medicine, Research & Experimental
H. Fischer, T. Maleitzke, C. Eder, S. Ahmad, U. Stoeckle, K. F. Braun
Summary: Proximal femur fractures are a leading cause of hospitalization in elderly patients and require careful perioperative management to reduce complications. Special attention should be given to the unique needs and comorbidities of elderly patients for optimal treatment outcomes.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Meike Gierig, Fangrui Liu, Lukas Weiser, Wolfgang Lehmann, Peter Wriggers, Michele Marino, Dominik Saul
Summary: The study demonstrates that a combination of spinopelvic stabilization and cross connector in Denis zone I sacrum fractures can significantly reduce the pressure in the fracture area under various loading conditions, providing significant biomechanical advantages.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Orthopedics
Bernhard W. Ullrich, Klaus J. Schnake, Ulrich J. A. Spiegl, Philipp Schenk, Thomas Mendel, Lars Behr, Philipp Bula, Laura B. Fluecht, Alexander Franck, Erol Gercek, Sebastian Grueninger, Philipp Hartung, Cornelius Jacobs, Sebastian Katscher, Friederike Klauke, Katja Liepold, Christian W. Mueller, Michael Mueller, Georg Osterhoff, Axel Partenheimer, Stefan Piltz, Marion Riehle, Daniel Sauer, Max Joseph Scheyerer, Philipp Schleicher, Gregor Schmeiser, Rene Schmidt, Matti Scholz, Holger Siekmann, Kai Sprengel, Dietrich Stoevesandt, Akhil Verheyden, Volker Zimmermann
Summary: The study successfully developed a simple and reliable CT- and MRI-based classification system for osteoporotic fractures of the pelvis, showing substantial inter-rater and almost perfect intra-rater reliability.
BMC MUSCULOSKELETAL DISORDERS
(2021)
