Journal
ORTHOPEDIC CLINICS OF NORTH AMERICA
Volume 41, Issue 1, Pages 85-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ocl.2009.07.004
Keywords
Nonunion; Bone defect; Autologous bone graft; Growth factors; Graft expansion; BMPs
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Although the unquestionable value of autologous bone grafting and the analogous value of the reaming by-products in nonunion treatment have been mentioned extensively in the literature, there is ongoing vivid discussion for the treatment of those case scenarios where the fracture nonunion is complicated by other local environment adverse circumstances. The graft expansion with growth factors as the bone morphogenetic proteins (BMPs) offers the possibility to reduce the number of operative procedures, complications, length of hospital stay, and time to union. In this article, we consider the potential clinical scenarios for graft expansion with BMPs.
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