Article
Orthopedics
Yoshikazu Sumida, Tomoyuki Nakasa, Masakazu Ishikawa, Atsuo Nakamae, Nobuo Adachi
Summary: In knee osteoarthritis, a lower Hounsfield unit value in the posterior cruciate ligament indicates more severe degeneration. The CT HU value can be a useful measurement to predict the grade of PCL degeneration.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tom D. Turmezei, Samantha B. Low, Simon Rupret, Graham M. Treece, Andrew H. Gee, James W. MacKay, John A. Lynch, Kenneth E. S. Poole, Neil A. Segal
Summary: Joint space mapping (JSM) of the knee using weight-bearing CT images is reproducible and feasible, showing a relationship between three-dimensional joint space width distribution and structural joint disease. Novice users can learn it reliably, and it can achieve a smallest detectable difference that is at least 50% smaller than that reported in radiography.
Editorial Material
Orthopedics
Mark Slabaugh
Summary: The treatment of osteoarthritis of the knee is a complex and significant issue with global impact. Various treatments focus on cartilage restoration procedures, but short-term studies have not shown improved clinical outcomes, leading to doubts about the effectiveness of longer-term studies.
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
(2023)
Article
Rehabilitation
Chen Huang, Ping-Keung Chan, Kwong-Yuen Chiu, Chun-Hoi Yan, Shun-Shing Yeung, Christopher Wai-Keung Lai, Aaron Kam-Lun Leung, Siu Ngor Fu
Summary: This study aimed to investigate the relationship between tibial torsion and gait kinematics in individuals with knee osteoarthritis (OA). The results showed that external tibial torsion was related to early stance knee flexion excursion in participants with moderate knee OA, but not in participants with mild knee OA. In addition, external tibial torsion was associated with external foot progression angle, and knee varus/valgus alignment was associated with knee flexion excursion.
BMC SPORTS SCIENCE MEDICINE AND REHABILITATION
(2023)
Article
Orthopedics
Xuequan Han, Junqi Cui, Linyang Chu, Weituo Zhang, Kai Xie, Xu Jiang, Zihao He, Jingke Du, Songtao Ai, Qi Sun, Liao Wang, Haishan Wu, Mengning Yan, Zhifeng Yu
Summary: The study found that abnormal knee alignment may lead to abnormal subchondral trabecular bone remodeling and microstructural changes, accelerating cartilage degradation and potentially affecting load stress transmission from cartilage to subchondral trabecular bone.
OSTEOARTHRITIS AND CARTILAGE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Dimitri N. Graf, Anne Thallinger, Veronika Zubler, Reto Sutter
Summary: This study found that intraarticular steroid injections have a lower rate of severe complications compared to previous smaller studies, but the rate of complications in women is disproportionately higher than in men.
Article
Orthopedics
Saeed Arbabi, Wouter Foppen, Willem Paul Gielis, Marijn van Stralen, Mylene Jansen, Vahid Arbabi, Pim A. de Jong, Harrie Weinans, Peter Seevinck
Summary: This study evaluated the performance of synthetic computed tomography (sCT), a novel MRI-based bone visualization technique, compared with CT, for the scoring of knee osteoarthritis. The results showed that sCT and CT were comparable for the scoring of knee OA.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Endocrinology & Metabolism
Rafael Heiss, Jean -Denis Laredo, Wolfgang Wirth, Mylene P. Jansen, Anne C. A. Marijnissen, Floris Lafeber, Agnes Lalande, Harrie H. Weinans, Francisco J. Blanco, Francis Berenbaum, Margreet Kloppenburg, Ida K. Haugen, Klaus Engelke, Frank W. Roemer
Summary: Objective: Osteoarthritis (OA) is a highly prevalent chronic condition, and the subchondral bone plays an important role in its onset and progression. This study aimed to investigate the changes in periarticular bone mineral density (BMD) in OA and its relation to meniscal coverage and meniscal extrusion at the knee.
Article
Rehabilitation
Mingyang Li, Yi Zeng, Yong Nie, Yuangang Wu, Yuan Liu, Limin Wu, Bin Shen
Summary: Long kneeling is associated with increased bone volume fraction and trabecular number, while long squatting is associated with decreased trabecular separation and increased trabecular thickness. Subchondral bone microarchitecture may be a useful monitoring indicator for knee osteoarthritis patients who engage in prolonged kneeling or squatting.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2022)
Article
Orthopedics
F. W. Roemer, K. Engelke, L. Li, J. -D. Laredo, A. Guermazi
Summary: This study aimed to investigate the diagnostic performance of routine MRI for assessing osteophytes in three knee compartments using CT as a reference standard. The study found that MRI underestimates the presence of osteophytes in all three compartments, and CT may be helpful in assessing small osteophytes, especially in early disease.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sherif Elsobky, Malavika Nathan, Nicola Robertson, Thomas Wagner
Summary: F-18-PSMA PET/CT imaging is increasingly used for staging, assessment of biochemical recurrence, and treatment response in men with prostate cancer. This case report demonstrates the identification of new focal moderate PSMA uptake in bone infarction, a previously unreported finding in English literature.
CLINICAL NUCLEAR MEDICINE
(2021)
Editorial Material
Medicine, General & Internal
Miju Cheon, Jang Yoo
Summary: Metastatic calcification caused by hypercalcemia can affect various organs. This case report describes a 71-year-old male with metastatic pulmonary calcification, diagnosed using FDG PET/CT and MDP bone scan.
Article
Medicine, General & Internal
Xiongjian Hu, Yiming Cao, Bin Ji, Min Zhao, Qiang Wen, Bin Chen
Summary: This study aimed to compare the diagnostic efficiency of F-18-DCFPyL PET/CT imaging and Tc-99m-MDP SPECT/CT bone imaging for detecting bone metastases in prostate cancer. The results showed that F-18-DCFPyL PET/CT imaging had superior diagnostic performance compared to Tc-99m-MDP SPECT/CT bone imaging at both the patient and lesion levels. It is concluded that F-18-DCFPyL PET/CT imaging is an important supplement to imaging examination for prostate cancer patients and has great potential and broad application prospects.
FRONTIERS IN MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Luz Herrero-Manley, Ana Alabajos-Cea, Luis Suso-Marti, Enrique Viosca-Herrero, Isabel Vazquez-Arce
Summary: The study aimed to test the practicality of the existing diagnostic criteria for early knee osteoarthritis (EKOA) and evaluate the clinical progression of both healthy subjects at risk and patients diagnosed with EKOA. The participants were classified into EKOA and healthy subjects based on disability, pain, and self-reported variables. Most participants remained in their original classification, although some were reclassified during the follow-ups. The current diagnostic criteria could lead to misdiagnosis due to fluctuations in patients' conditions.
Review
Medicine, General & Internal
Daniel Veloz Serrano, Samundeeswari Saseendar, Saseendar Shanmugasundaram, Rohan Bidwai, Diego Gomez, Riccardo D'Ambrosi
Summary: Osteonecrosis is a serious condition that can cause advanced arthritis in multiple joints, including the knee. Treatment options include joint replacement and joint preservation surgery, while non-operative treatments include observation, medication, and protective weight bearing.
JOURNAL OF CLINICAL MEDICINE
(2022)