A diverse array of genetic factors contribute to the pathogenesis of Systemic Lupus Erythematosus

Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus

(2011) Paula S. Ramos et al.   ARTHRITIS AND RHEUMATISM

Two-step cleavage of hairpin RNA with 5' overhangs by human DICER

(2011) Yoshinari Ando et al.   BMC MOLECULAR BIOLOGY

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

(2011) B Namjou et al.   GENES AND IMMUNITY

Histone Deacetylase 9 Deficiency Protects against Effector T Cell-mediated Systemic Autoimmunity

(2011) Kailin Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A20-binding inhibitor of NF- B (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein   activation and protects from inflammatory disease

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases

(2011) Rujuan Dai et al.   Translational Research

Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models

(2011) Simanta Pathak et al.   ARTHRITIS RESEARCH & THERAPY

A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

(2011) Xiaobing Luo et al.   PLoS Genetics

MicroRNAs of the immune system

(2010) Jan Davidson-Moncada et al.   Annals of the New York Academy of Sciences

MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus

(2010) Xia Zhao et al.   ARTHRITIS AND RHEUMATISM

Association of a functional polymorphism in the 3′-untranslated region of SPI1 with systemic lupus erythematosus

(2010) Koki Hikami et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1

(2010) Sha Zhao et al.   ARTHRITIS AND RHEUMATISM

MicroRNAs: Synthesis, mechanism, function, and recent clinical trials

(2010) Fazli Wahid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Dicer Insufficiency and MicroRNA-155 Overexpression in Lupus Regulatory T Cells: An Apparent Paradox in the Setting of an Inflammatory Milieu

(2010) A. A. Divekar et al.   JOURNAL OF IMMUNOLOGY

Serum and Urinary Cell-free MiR-146a and MiR-155 in Patients with Systemic Lupus Erythematosus

(2010) G. WANG et al.   JOURNAL OF RHEUMATOLOGY

Interleukin 4 and STAT6 gene polymorphisms are associated with systemic lupus erythematosus in Chinese patients

(2010) H-H. Yu et al.   LUPUS

Genetic susceptibility to systemic lupus erythematosus in the genomic era

(2010) Yun Deng et al.   Nature Reviews Rheumatology

Genetics of SLE: evidence from mouse models

(2010) Laurence Morel   Nature Reviews Rheumatology

Identification of Unique MicroRNA Signature Associated with Lupus Nephritis

(2010) Jeannie L. Te et al.   PLoS One

Identification of a Common Lupus Disease-Associated microRNA Expression Pattern in Three Different Murine Models of Lupus

(2010) Rujuan Dai et al.   PLoS One

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

microRNAs and the immune response

(2009) Eleni Tsitsiou et al.   CURRENT OPINION IN PHARMACOLOGY

Meta-analysis in genome-wide association studies

(2009) Eleftheria Zeggini et al.   PHARMACOGENOMICS

Lupus in the developing world – is it any different?

(2008) Mohammed Tikly et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Increased glomerular matrix metalloproteinase activity in murine lupus nephritis

(2008) Anders A. Tveita et al.   KIDNEY INTERNATIONAL

Apoptosis in the pathogenesis of systemic lupus erythematosus

(2008) LE Munoz et al.   LUPUS

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients

(2008) Yong Dai et al.   RHEUMATOLOGY INTERNATIONAL

Developments in the scientific understanding of lupus

(2008) Stacy P Ardoin et al.   ARTHRITIS RESEARCH & THERAPY

What Can Genome-Wide Association Studies Tell Us about the Genetics of Common Disease?

(2008) Mark M Iles   PLoS Genetics