Article
Genetics & Heredity
A. M. J. van Wegberg, A. MacDonald, D. Abeln, T. S. Hagedorn, E. Lange, F. Trefz, D. van Vliet, F. J. van Spronsen
Summary: In this study, most participants expected that assigning centres of expertise for Phenylketonuria would change the structure and delivery of PKU care. Distance was reported as a major barrier, and participants also emphasized the importance of having CE physicians and dieticians with a higher level of knowledge than in non-CE centres. Collaboration with patient associations was also seen as crucial by a majority of participants.
ORPHANET JOURNAL OF RARE DISEASES
(2021)
Article
Oncology
M. Bencivenga, L. Torroni, G. Verlato, V. Mengardo, M. Sacco, W. H. Allum, G. de Manzoni
Summary: This study evaluated the current practice of D2 in Europe, showing that tumor histology significantly affects surgeons' choice in lymphadenectomy extent. While almost all cases achieved adequate lymphadenectomy in dedicated centers, there is still variation in the number of retrieved nodes.
Article
Economics
Alexandros Bartzokas-Tsiompras, Efthimios Bakogiannis, Alexandros Nikitas
Summary: This study presents a new Microscale Walkability Index that measures the pedestrian-friendliness of city centers in Europe. The results show that Barcelona, Bilbao, Oslo, Zurich, and Paris are the most pedestrian-friendly city centers, while Bucharest, Athens, Sofia, Plovdiv, and Palermo rank the lowest. The study also finds that cities with higher GDP per capita, a higher proportion of walking/cycling, and better sustainability performance have higher microscale walkability rankings.
JOURNAL OF TRANSPORT GEOGRAPHY
(2023)
Article
Chemistry, Physical
Charles Babin, Rainer Stoehr, Naoya Morioka, Tobias Linkewitz, Timo Steidl, Raphael Woernle, Di Liu, Erik Hesselmeier, Vadim Vorobyov, Andrej Denisenko, Mario Hentschel, Christian Gobert, Patrick Berwian, Georgy Astakhov, Wolfgang Knolle, Sridhar Majety, Pranta Saha, Marina Radulaski, Nguyen Tien Son, Jawad Ul-Hassan, Florian Kaiser, Joerg Wrachtrup
Summary: Optically addressable spin defects in silicon carbide (SiC) are a promising platform for quantum information processing, enabling high-fidelity spin qubit operations. However, degradation of spin-optical coherence after integration in nanophotonic structures poses a challenge for scalability towards large-scale quantum networks.
Article
Computer Science, Artificial Intelligence
Hiran H. Lathabai, Abhirup Nandy, Vivek Kumar Singh
Summary: The article presents an institutional collaboration recommendation system that can help institutions identify potential collaborators, determine and improve the research portfolio of an institution within a field, and ultimately enhance the institution's performance in that field. The framework is demonstrated through analyzing the performance of 195 Indian institutions in the field of 'Computer Science', and validation shows it has sufficient coverage and can provide novel and diverse recommendations.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Humanities, Multidisciplinary
Camille Bellet, Lindsay Hamilton, Jonathan Rushton
Summary: This study argues for a new scientific logic of routine animal health care in industrial farming in Europe and highlights how the social regime underpinning scientific research on chronic animal disease management stifles innovation. Findings show that research on CADM in major sectors of the European food industry is focused on growth, profitability, and control rather than addressing the interconnectedness between chronic animal diseases, the food industry, and people. This study contributes to the literature by drawing attention to chronic animal diseases that are non-transmissible to humans and expanding the conceptualization of One Health to include chronic animal health conditions.
HUMANITIES & SOCIAL SCIENCES COMMUNICATIONS
(2021)
Article
Green & Sustainable Science & Technology
Minyoung Kwon, Erwin Mlecnik, Vincent Gruis
Summary: While local authorities could potentially use business model approaches for the development of pop-up home renovation consultancy centres, the specific strategies needed for various customer segment groups were lacking, highlighting the need for further investigation into traditional business models for local authority activities.
Article
Environmental Studies
Alexandros Bartzokas-Tsiompras, Eleftheria Konstantinidou
Summary: Graffiti in urban areas takes various forms and materials, ranging from simple spray slogans to wall paintings and art with diverse content. Despite conflicting opinions in literature, studies have shown a positive association between wall-graffiti and fear of crime or streetscape value. However, there is a lack of comparative urban studies on graffiti locations, which hinders the benchmarking of urban liveability. This study investigated the spatial patterns of graffiti-vandalism in 30 European city centres using Google Street View-derived observations, revealing significant variations across Europe and highlighting the presence of socio-spatial inequities.
ENVIRONMENT AND PLANNING B-URBAN ANALYTICS AND CITY SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Babunageswararao Kanuri, Vincent Fong, Sithara Raju Ponny, Keri A. Tallman, Sriganesh Ramachandra Rao, Ned Porter, Steven J. Fliesler, Shailendra B. Patel
Summary: Researchers have generated a conditional Dhcr7 knockout mouse model with liver-specific deletion, which demonstrated minimal impact on sterol metabolism in the liver. This model provides a valuable tool for further exploration of the pathophysiology of SLOS through temporal, cell and tissue-specific loss of DHCR7.
JOURNAL OF LIPID RESEARCH
(2021)
Article
Infectious Diseases
Gert Van der Auwera, Leigh Davidsson, Pierre Buffet, Marie-Therese Ruf, Marina Gramiccia, Stefania Varani, Carmen Chicharro, Aldert Bart, Gundel Harms, Peter L. Chiodini, Hanne Brekke, Florence Robert-Gangneux, Sofia Cortes, Jaco J. Verweij, Alessandra Scarabello, Sara Karlsson Sobirk, Romain Guery, Saskia van Henten, Trentina Di Muccio, Elena Carra, Pieter van Thiel, Martin Vandeputte, Valeria Gaspari, Johannes Blum
Summary: This study collected retrospectively records of leishmaniasis cases diagnosed in 15 centers between 2014 and 2019, and analyzed data on country of infection, reason for traveling, infecting species, age, and sex. The results showed that visceral leishmaniasis was mainly acquired in Europe, while cutaneous leishmaniasis was primarily imported from outside Europe. The geographic species distribution largely confirmed known epidemiology, with some exceptions. The study highlights the importance of pooling species typing data from multiple centers to monitor changing epidemiology.
Article
Chemistry, Medicinal
Heng Zhang, Yunfan Gao, Guangcheng Fu, Junzhong Liu, Qingcai Jiao
Summary: The European Journal of Medicinal Chemistry (EJMC) has been widely recognized and studied by researchers in the field. A bibliometric analysis was conducted to assess the scientific output and current status of EJMC from 1987 to 2022. The analysis identified the countries, institutions, authors, and literature with the highest impact, and used visualization networks to present the findings. The keyword co-occurrence analysis revealed a shift from phenotypic drug discovery to target-based drug discovery, and provided insights for researchers to define their research topics and directions. The focus of research in EJMC has shifted towards antitumor and oxidative stress-related drugs, with future studies focusing on tumor multidrug resistance, oxidative stress, and dual inhibitors.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Review
Multidisciplinary Sciences
Ester M. M. Cardinaal, Heleen N. W. Duighuisen, Patrick P. T. Jeurissen, Hubert Berden
Summary: This scoping review aims to understand the scope and type of evidence related to the organization of European Academic Medical Centers (AMCs). The study included 108 sources and found variations in the organizational structure of European AMCs, suggesting a need for further research to explain these differences.
Article
Management
Hamish Thorburn, Anna-Lena Sachs, Jamie Fairbrother, John E. Boylan
Summary: This article discusses a staff allocation problem at a sequential sorting facility and proposes a new time-expanded network flow model to solve it. The model addresses multiple objectives and operational requirements through a lexicographical approach. By applying the model to a UK mail centre case, its effectiveness is validated, and its performance in different scenarios is demonstrated.
JOURNAL OF THE OPERATIONAL RESEARCH SOCIETY
(2023)
Article
Cardiac & Cardiovascular Systems
Corina Thomet, Markus Schwerzmann, Werner Budts, Julie De Backer, Massimo Chessa, Gerhard Diller, Andreas Eicken, Harald Gabriel, Pastora Gallego, Alessandro Giamberti, Jolien Roos-Hesselink, Lorna Swan, Gary Webb, Philip Moons
Summary: The study surveyed existing transfer and transition programmes in European ACHD centres and found that nearly half of the centres offered a formal transition programme, while almost all centres had structured transfer from paediatric to ACHD care. However, most programs lacked an age and development-based approach despite some improvements since 2009.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Environmental Studies
Adam B. Weinberger, Eleanor W. Garside, Alexander P. Christensen, Anjan Chatterjee
Summary: The aesthetics of the built and natural environment are influenced by individuals' expertise in architecture and design, resulting in different psychological dimensions and preferences.
JOURNAL OF ENVIRONMENTAL PSYCHOLOGY
(2022)
