Article
Multidisciplinary Sciences
Korey P. Carter, Katherine M. Shield, Kurt F. Smith, Zachary R. Jones, Jennifer N. Wacker, Leticia Arnedo-Sanchez, Tracy M. Mattox, Liane M. Moreau, Karah E. Knope, Stosh A. Kozimor, Corwin H. Booth, Rebecca J. Abergel
Summary: Transplutonium elements are a group of metals at the edge of the periodic table, with properties that are less predictable due to their scarcity and radioactivity. Studies on the heaviest element einsteinium highlight the need for further exploration of actinide elements, especially those that are scarce and short-lived.
Article
Engineering, Environmental
Zhipeng Yin, Li Ye, Wen Zhong, Chuanyong Jing
Summary: A previously unknown antimony species, trimethylmonothioantimony (TMMTSb), was identified and characterized, forming when trimethylantimony (TMSb) reacted with sulfide. The research sheds light on the chemical species of antimony in the environment and may have implications for its fate.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Hironobu Hojo, Toshiki Takei, Yuya Asahina, Nobuaki Okumura, Toshifumi Takao, Masatomo So, Isao Suetake, Takeshi Sato, Akihiro Kawamoto, Yoshio Hirabayashi
Summary: In this study, the essential protein Caveolin-1 for caveola formation was chemically synthesized and successfully inserted into the lipid bilayer to form a V-shaped structure. The solid-phase method was used to synthesize peptide segments, and O-acyl isopeptide structures were incorporated to improve solubility. After ligation by the thioester method and the introduction of palmitoyl groups, the obtained polypeptide was inserted into bicelles.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biochemistry & Molecular Biology
Felix J. Metzner, Elisabeth Huber, Karl-Peter Hopfner, Katja Lammens
Summary: The Schlafen family, including SLFN5, plays important roles in cell cycle regulation, DNA repair, etc. The structure of SLFN5 differs from ATPase and can bind both tRNA and DNA, possibly involved in transcriptional regulation.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Chemistry, Inorganic & Nuclear
M. Jake Pushie, Kelly L. Summers, Kurt H. Nienaber, Ingrid J. Pickering, Graham N. George
Summary: Cuprizone is a ligand that forms intensely colored blue complexes with copper ions and can be used to detect trace levels of copper. It has also been found to induce demyelination and is commonly used to create animal models of demyelination. However, there have been limited studies on the structural characterization of the copper coordination properties of cuprizone.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Applied
Arland T. Hotchkiss, Hoa K. Chau, Gary D. Strahan, Alberto Nunez, Stefanie Simon, Andre K. White, Senghane Dieng, Eugene R. Heuberger, Madhav P. Yadav, Julie Hirsch
Summary: The composition, structure, and functional relationships of various red beet fiber fractions were determined. Red beet pomace contained mainly insoluble dietary fiber, with pectin as the major polysaccharide. The structural properties of these fractions suggest that they can thicken and stabilize food systems, and the pectin fractions show potential as a prebiotic food ingredient.
FOOD HYDROCOLLOIDS
(2022)
Review
Chemistry, Multidisciplinary
Robert L. Green
Summary: Rare-earth-containing phosphors are crucial for compact fluorescent lamps (CFLs) to protect halophosphate phosphors from degradation. The two layer coating of cheap halophosphate phosphor and a light coat of rare-earth-containing phosphors generates white light with high efficacy and good color rendering index. Investigating Sr3AlO4F and Ba2SrGaO4F as potential phosphors can help reduce phosphor costs by requiring lower rare-earth ion concentrations or eliminating them completely.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Chemistry, Applied
Xiaoqing Ma, Yangying Sun, Daodong Pan, Jinxuan Cao, Yali Dang
Summary: Phosphorylation modification by STP can enhance the stability of hemoglobin through structural changes, making phosphorylated NO-Hb more stable than NO-Hb in various conditions. Absorbance of P-NO-Hb is higher and decreases more slowly over time compared to Hb and NO-Hb.
Article
Biochemistry & Molecular Biology
Pengjiao Hou, Wei Hao, Bo Qin, Mengyun Li, Rong Zhao, Sheng Cui
Summary: Schlafen11 is a well-studied protein that plays important roles in cancer therapy and virus-host interactions. The crystal structure and biochemical characteristics of the N-terminal domain (NTD) of Schlafen11 were determined, revealing its potent RNase activity towards type I and II tRNAs and rRNAs. These findings enhance our understanding of the Schlafen family.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
V. Mahesh Krishnan, Dimitar Y. Shopov, Caitlin J. Bouchey, Wilson D. Bailey, Riffat Parveen, Bess Vlaisavljevich, William B. Tolman
Summary: By modulating the properties of ligands, Cu(III) complexes bearing an oxygen-based auxiliary ligand were successfully stabilized and characterized for the first time, showing enhanced stability and slower reactivity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Review
Chemistry, Applied
Mingjun Zhang, Ahui Zhan, Ying Ye, Cancan Liu, Fangxue Hang, Kai Li, Jianbin Li
Summary: Xylans have various biological activities due to differences in their source and structure, but their activities are lower than commercial drugs due to structural limitations. Various molecular modification methods have been developed to address these limitations and obtain derivatives with specific biological activity. Further research on structural characteristics, structure-activity relationship, and mechanism of action of xylan derivatives is significant for their development.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Shiqiang Wang, Gang Li, Xinfei Zhang, Yuqian Wang, Yi Qiang, Bulei Wang, Jiabin Zou, Junfeng Niu, Zhezhi Wang
Summary: Polysaccharides obtained from Polygonatum sibiricum (PSP) were purified and characterized in this study. The PSP1 sample had the highest content and best solubility. The main sugar residue linkages were identified as 1)-beta-D-Fruf-(2 -> 1)-beta-D-Fruf-(2 -> 1), 1 -> -beta-D-Fruf-(2 -> 6)alpha-D-Glcp (1 ->,-> 4)-beta-D-Manp-(1 -> 4)-beta-D-Manp-(1 -> and -> 6)-beta-D-Glcp-(1 -> 4)-beta-D-Manp-(1 ->. Branch chain analysis revealed the presence of -> 1,6)-beta-D-Fruf-(2 ->, beta-D-Fruf-(2 ->,-> 1,6)-beta-D-Fruf-(2 ->,-> 6)-beta-D-Fruf(2 -> linkages, with the link site at position C-6. In vitro antioxidant activity tests showed that PSP1 had scavenging effects on DPPH, hydroxyl radical, superoxide anion radical, and exhibited a specific chelating ability for ferrous ions. These findings suggest that P. sibiricum polysaccharides may possess potential antioxidant properties.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Kevin Voth, Shivani Pasricha, Ivy Yeuk Wah Chung, Rachelia R. Wibawa, Engku Nuraishah Huda E. Zainudin, Elizabeth L. Hartland, Miroslaw Cygler
Summary: Legionella pneumophila is a Gram-negative intracellular pathogen causing Legionnaires' disease, using a secretion system and effector proteins to colonize host cells. MavL may play a role in cell signaling by binding ADP-ribose, and interacts with the mammalian ubiquitin-conjugating enzyme.
Article
Cardiac & Cardiovascular Systems
Marta Perez-Hernandez, Alejandra Leo-Macias, Sarah Keegan, Mariam Jouni, Joon-Chul Kim, Esperanza Agullo-Pascual, Sarah Vermij, Mingliang Zhang, Feng-Xia Liang, Paul Burridge, David Fenyo, Eli Rothenberg, Mario Delmar
Summary: This study identified a subcellular domain formed by sodium channel clusters and subjacent subsarcolemmal mitochondria in adult cardiac myocytes, shedding light on the intersection between electrical and structural functions of the heart. The proximity of Na(V)1.5 channels to mitochondria resulted in functional changes in mitochondria upon TTX exposure, with increased Ca2+ accumulation and reactive oxygen species production. Additionally, a negative correlation between SCN5A and SLC8B1 at a transcriptional level was observed, highlighting the intricate crosstalk between sodium channels and mitochondria.
CIRCULATION RESEARCH
(2021)
Article
Multidisciplinary Sciences
Tamara Hoffmann, Devid Mrusek, Patricia Bedrunka, Fabiana Burchert, Christopher-Nils Mais, Daniel B. Kearns, Florian Altegoer, Erhard Bremer, Gert Bange
Summary: Biofilm formation in Bacillus subtilis requires the expression of matrix production genes, which are upregulated by the transcriptional activator RemA. The study revealed that RemA forms octameric rings with the potential to form a 16-meric superstructure, and it can wrap DNA through a LytTR-related domain.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Christoph Helling, Chelladurai Ganesamoorthy, Christoph Woelper, Stephan Schulz
Summary: The activation of E-X sigma-bonds by gallanediyl LGa (L = HC[C(Me)N(Dip)](2), Dip = 2,6-i-Pr2C6H3) has been confirmed in this study. Reactions of LGa with chloromethanes and chlorosilanes EHxCl4-x (E = C, x = 0-2; E = Si, x = 0, 1) resulted in E-Cl bond insertion and the formation of gallylmethanes and -silanes. Consecutive insertion into a geminal E-Cl bond was observed with two equivalents of LGa.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Alexander Gehlhaar, Christoph Woelper, Felix Van der Vight, Georg Jansen, Stephan Schulz
Summary: Five peri-substituted naphthalene and acenaphthalene complexes were synthesized and characterized, showing different types of noncovalent intermolecular interactions in the solid-state. Density functional theory calculations demonstrated that the Bi....pi contact provided the main stabilizing contribution, with London dispersion interactions dominating these contacts.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Juliane Schoening, Christoph Woelper, Stephan Schulz
Summary: We report on the reactions of heteroleptic metallasilylenes with CO2, N2O, and Me3SiN3, resulting in the formation of corresponding carbonate complexes, silanoic esters, and silaimine. In addition, a new compound was synthesized through C-C bond cleavage.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Review
Polymer Science
Eduard Gloeckler, Swarup Ghosh, Stephan Schulz
Summary: This review highlights the ongoing developments in the ring-opening polymerization of lactide and caprolactone using beta-diketiminate and beta-ketoiminate metal complexes. The resulting aliphatic polyesters could serve as sustainable replacements to petrochemicals-based polymers, with potential applications in tissue engineering, bio-medical, and agricultural sciences.
Article
Chemistry, Inorganic & Nuclear
Bin Li, Christoph Woelper, Stephan Schulz
Summary: In this study, the researchers reported on the reaction between a new compound LGa and bromoalkanes, which can achieve C-Br bond activation. Different products can be obtained by changing the molar ratio of reactants. The products were characterized by NMR, IR, and X-ray diffraction.
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE
(2023)
Article
Chemistry, Multidisciplinary
Swapnil Varhade, E. B. Tetteh, Sascha Saddeler, Simon Schumacher, H. B. Aiyappa, Georg Bendt, Stephan Schulz, Corina Andronescu, Wolfgang Schuhmann
Summary: Scanning electron microscopy and atomic force microscopy images of droplet landing sites are correlated with the electrocatalytic activity for the oxygen evolution reaction in alkaline electrolyte of hexagonal spinel Co3O4 nanoparticles derived using scanning electrochemical cell microscopy. The turnover frequency (TOF) of surface Co atoms is used to deconvolute the intrinsic catalytic activity of individual crystal facets of the hexagonal Co3O4 spinel particle. The top surface exposing 111 crystal planes showed a thickness-dependent TOF, while the edge of the particle exposing (110) planes showed a higher average TOF and no correlation with particle thickness.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Janis Timoshenko, Felix T. Haase, Sascha Saddeler, Martina Ruescher, Hyo Sang Jeon, Antonia Herzog, Uta Hejral, Arno Bergmann, Stephan Schulz, Beatriz Roldan Cuenya
Summary: By using operando quick X-ray absorption fine structure spectroscopy and unsupervised/supervised machine learning methods, we can unveil the real active species and active states in bimetallic transition-metal oxide catalysts. Through principal component analysis and artificial neural network analysis, we can track the evolution of tetrahedrally and octahedrally coordinated species and understand the chemical changes and phase transitions taking place in CoxFe3-xO4 catalysts.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Inorganic & Nuclear
Bin Li, Hanns Micha Weinert, Christoph Woelper, Stephan Schulz
Summary: Oxidative addition reactions of LZnH with L1Si and L2SiNMe2 yielded L1Si(H)-ZnL (1) and LH2Si(NMe2)ZnL (3), while the reaction with L2SiCl proceeded with H/Cl ligand exchange and the formation of L2Si(H)-Zn(Cl)L (2). Protonation reaction of 1 with H-(OEt2)2BArF4 gave LS(H)-ZnL (4). The nature of the Zn-Si bond in 1-4 was evaluated by quantum chemical calculations, showing that the Si-Zn bond in 1 and 3 is covalent, while those in 2 and 4 are better described as dative bonds.
Editorial Material
Chemistry, Inorganic & Nuclear
Stephan Schulz, Christian Mueller
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE
(2023)
Article
Chemistry, Multidisciplinary
Hanns M. Weinert, Christoph Woelper, Stephan Schulz
Summary: Monovalent group 13 diyls are used as versatile reagents in oxidative addition reactions, and the [1,4]-cycloaddition reactions of these diyls with various 1,2-diketones are reported here. These reactions result in the formation of different compounds, and additional reactions with other compounds such as aldehydes and benzene rings were also studied.
CHEMISTRY-SWITZERLAND
(2023)
Article
Chemistry, Multidisciplinary
Mahendra K. Sharma, Hanns M. Weinert, Bin Li, Christoph Woelper, Justin T. Henthorn, George E. Cutsail III, Gebhard Haberhauer, Stephan Schulz
Summary: Based on DFT calculations, LGa(P2OC)cAAC 2 possesses a delocalized p-type HOMO and p*-type LUMO due to the presence of a 1,2-diphospha-1,3-butadiene moiety. Reaction of 2 with KC8 and dibenzo-18-crown-6 led to the isolation of [LGa(P2OC)cAAC][K(DB-18-c-6)] 3[K(DB-18-c-6] containing the 1,2-diphospha-1,3-butadiene radical anion 3*. Further reactions of 3 with [Fc][B(C6F5)(4)] and TEMPO yielded 2 and [L-HGa-(P2OC)cAAC][K(DB-18-c-6)] 4[K(DB-18-c-6] respectively, with the latter containing the 1,2-diphospha-1,3-butadiene anion 4-. The structures of 2, 3[K(DB-18-c-6], and 4[K(DB-18-c-6] were determined using single crystal X-ray diffraction (sc-XRD).
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Hanns M. Weinert, Yannick Schulte, Alexander Gehlhaar, Christoph Woelper, Gebhard Haberhauer, Stephan Schulz
Summary: This article reports the synthesis and solid-state structures of DMAP-coordinated GaPn complexes, where Pn is Sb and Bi. In addition, the synthesis of base-free dipnictene dications is also reported. Quantum chemical calculations show that the dications 5(2+) and 6(2+) are isoelectronic analogues of the butadiene dication.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Xiaofei Sun, Alexander Hinz, Stephan Schulz, Lisa Zimmermann, Manfred Scheer, Peter W. Roesky
Summary: Insertion and functionalization of gallasilylenes into the cyclo-E-5 rings of [Cp*Fe(?(5)-E-5)] (E = P, As) have been reported. The reaction results in E-E/Si-Ga bond cleavage and the insertion of the silylene in the cyclo-E-5 rings. The isolated complexes represent rare examples of mixed group 13/14 iron polypnictogenides, which can only be synthesized by utilizing the cooperativity of gallatetrylenes.
Article
Chemistry, Multidisciplinary
Mahendra K. Sharma, Hanns M. Weinert, Bin Li, Christoph Woelper, Justin T. Henthorn, George E. Cutsail, Gebhard Haberhauer, Stephan Schulz
Summary: LGa(P2OC)cAAC2 features a unique structure with conjugated HOMO and LUMO. Compounds containing 1,2-diphospha-1,3-butadiene radical and anion were obtained through reactions. The solid-state structures of these compounds were determined by X-ray diffraction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Eduard Gloeckler, Leon Kapp, Christoph Woelper, Marcel Schumacher, Andre H. Groeschel, Stephan Schulz
Summary: In this study, three zinc complexes were synthesized and characterized using various techniques. The results indicated that heteroleptic complex 2 exhibited the highest activity and selectivity in the ring-opening polymerization reaction.
