Journal
ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 18, Issue 8, Pages 1041-1044Publisher
AMER CHEMICAL SOC
DOI: 10.1021/op500121w
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Funding
- NIH (NIH-NIGMS) [GM088237]
- Daiichi-Sankyo Co., Ltd.
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We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.
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