Journal
ORGANIC LETTERS
Volume 20, Issue 18, Pages 5960-5963Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b02671
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Funding
- Hefei University of Technology
- NSFC [21401037, 21672049]
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A new class of rhodium-catalyzed, C-H activation triggered [3 + 2] annulations of aromatic aldimines or ketimines and maleimides was reported in this study. A broad scope of general imines without electron-withdrawing groups were successfully activated and could effectively react with N-substituted maleimide to afford pericyclic, multichiral centered amines in good yields and with excellent diastereoselectivity.
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