Journal
ORGANIC LETTERS
Volume 16, Issue 11, Pages 3016-3019Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol501136e
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Funding
- National Institutes of Health [T32 GM008804]
- University of Arizona
- Caldwell Health Sciences Research Fellowship
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An expeditious one-pot, ligand-free, Pd(OAc)(2)-catalyzed, three-component reaction for the synthesis of 2,3-diarylimidazo[1,2-alpha]pyridines was developed under microwave irradiation. With the high availability of commercial reagents and great efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of 2,3diarylirnidazo[1,2-alpha]pyridines analogues.
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