Journal
ORGANIC LETTERS
Volume 15, Issue 8, Pages 1942-1945Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol4005917
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Funding
- General Medical Sciences of the National Institutes of Health [GM083944-05]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM083944] Funding Source: NIH RePORTER
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A mild and highly efficient Cu(I)catalyzed oxidative coupling of anilines is described. Various primary and secondary anilines can be efficiently coupled under mild conditions to the corresponding azo compounds and hydrazines in high yields. This method provides a direct and practical access to these compounds and is also amenable to gram scale with no special precautions to exclude air or moisture.
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