Journal
ORGANIC LETTERS
Volume 15, Issue 6, Pages 1354-1357Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol400380y
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Funding
- European Research Council under the European Community [257891]
- EPFL
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The synthesis of cyclopropyl spiroindolines is described using an intramolecular palladium(0)-catalyzed C-H functionalization of a methine C(sp(3))-H bond. This transformation can be coupled with intermolecular Suzuki couplings or direct arylations of heteroaromatics to access functionalized indoline scaffolds in a single step.
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