Journal
ORGANIC LETTERS
Volume 14, Issue 4, Pages 957-959Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol300067h
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Funding
- National Basic Research Program of China [2011CB936003]
- Natural Science Foundation of China [21072169]
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A novel copper-catalyzed annulation of 2-alkylazaarenes with alpha,beta-unsaturated carboxylic acids has been accomplished. This reaction featuring C-H olefination and decarboxylative amination processes provides a concise access to C-2 arylated indolizines from simple and readily available starting materials.
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