Journal
ORGANIC LETTERS
Volume 13, Issue 3, Pages 534-536Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1028817
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- Delegation Generale de l'Armement
- ENSTA
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Two different Smiles rearrangements can be combined to afford a multicomponent formation of isoquinolinones and isoindolinones from nitro methyl salicylate. After a Ugi-Smiles four-component coupling, the base-triggered cyclization of the resulting adduct is followed by a ring contraction via a Truce-Smiles rearrangement.
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