Journal
ORGANIC LETTERS
Volume 12, Issue 18, Pages 4014-4017Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol1016228
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Funding
- NNSF of China [20953002, 60778033]
- 863 Program [2009AA03Z318]
- National Basic Research Program of China [2006CB933000, 2007CB936001]
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N,N-Dimethyl-N-(pyrenyl-1-methyl) dodecan-1-ammonium has been designed and applied as a fluorescent probe for sensing bacterial endotoxin. Upon assembly with bacterial endotoxin (lipopolysaccharide) in aqueous solution, the probe exhibits a ratiometric and sensitive fluorescence response with a low detection limit (100 nM). Moreover, the probe shows high selectivity for bacterial endotoxin over other related biological species.
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