4.8 Article

Synthesis of (±)-Chamobtusin A by a Presumed Biomimetic Aza-Cyclization

Journal

ORGANIC LETTERS
Volume 12, Issue 21, Pages 4709-4711

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol101846z

Keywords

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology, Japan [21780108]
  2. Grants-in-Aid for Scientific Research [21780108] Funding Source: KAKEN

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A total synthesis of (+/-)-chamobtusin A has been accomplished on the basis of our presumed biosynthetic pathway: the imine formation of keto aldehyde followed by intramolecular aza-Michael addition.

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