Journal
ORGANIC LETTERS
Volume 11, Issue 20, Pages 4612-4615Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol901891u
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Funding
- Major Basic Research Development Program [2006CB806106]
- National Natural Science Foundation of China [20532050, 20872161, 20821002]
- Chinese Academy of Sciences
- Croucher Foundation of Hong Kong
- Science and Technology Commission of Shanghai Municipality
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Enamines served as carbon-nucleophiles for the first time in the Cu-catalyzed asymmetric propargylic substitution reaction of propargylic acetates, providing corresponding chiral beta-ethynyl-substituted ketones in high yields and in good to high enantioselectivity.
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