4.8 Article

ortho-Lithiophenyl Isocyanide: A Versatile Precursor for 3H-Quinazolin-4-ones and 3H-Quinazolin-4-thiones

Journal

ORGANIC LETTERS
Volume 11, Issue 2, Pages 389-392

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol802659m

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Funding

  1. Land Niedersachsen
  2. Degussa-Stiftung (Evonik Industries AG)

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ortho-Lithiophenyl isocyanide has been generated from ortho-bromophenyl isocyanide and successfully employed toward the synthesis of 2-substituted phenyl isocyanides as well as 2,3-disubstituted 3H-quinazoline-4-ones and 3H-quinazolin-4-thiones.

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