4.8 Article

Aldol-Type Chirons from Asymmetric Hydrogenations of Trisubstituted Alkenes

Journal

ORGANIC LETTERS
Volume 11, Issue 10, Pages 2053-2056

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol900308w

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Funding

  1. National, Science Foundation [CHE-0750193]
  2. Robert A. Welch Foundation
  3. Division Of Chemistry
  4. Direct For Mathematical & Physical Scien [0750193] Funding Source: National Science Foundation

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Catalyst control dominates in the asymmetric hydrogenations of largely unfunctionalized trisubstituted alkenes formed from lactic acid and glyceraldehyde, affording syn- and ant aldol products of the type shown above.

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