4.8 Article

Copper-Catalyzed 2:1 Coupling Reaction of Arynes with Alkynes

Journal

ORGANIC LETTERS
Volume 11, Issue 2, Pages 373-376

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol802609j

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A formal insertion reaction of two molar amounts of arynes into a C-H bond of terminal alkynes is efficaciously catalyzed by copper(I) chloride, giving 2-alkynylbiaryls in one step.

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