Journal
ORGANIC LETTERS
Volume 10, Issue 19, Pages 4211-4214Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol801510n
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A one-pot synthesis of benzofurans which utilizes a palladium-catalyzed enolate arylation is described. The process demonstrates broad substrate scope and provides differentially substituted benzofurans in moderate to excellent yields. The utility of the method is further demonstrated by the synthesis of the natural product eupomatenoid 6 in three steps.
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