Article
Engineering, Environmental
Goksu Celik, Stefan Stolte, Susann Muller, Florian Schattenberg, Marta Markiewicz
Summary: This study investigated the biodegradability of heterocyclic PAHs and found that nine compounds were non-readily biodegradable. After one year of adaptation, the bacterial community developed the ability to mineralize carbazole but became more sensitive to the toxic effects of benzo[c]carbazole. The results were partially consistent with in silico models regarding biodegradation and sorption. This study provides valuable insights into the persistence of heterocyclic PAHs in aquatic environments.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Energy & Fuels
Jizhen Zhang, Denglin Han, Chenchen Wang, Wei Lin, Huiwen Zhang, Shuo Li
Summary: Type III kerogen plays a crucial role in understanding the adsorption and enrichment mechanisms of shale gas. Molecular simulation offers valuable insights into the physical and structural properties of kerogen, supporting the investigation at a molecular level. The results show that type III kerogen exhibits stronger adsorption capacity for C2H6 compared to CH4.
PETROLEUM SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Tara L. Salter, Jonathan S. Watson, Mark A. Sephton
Summary: Organic matter in sediments is mainly composed of kerogen, which can be classified into different types for paleoenvironmental and petroleum potential information. However, the presence of minerals in sediments can affect the chemical reactions of kerogen, leading to incorrect assignment of kerogen types and misleading interpretations.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2023)
Article
Clinical Neurology
Lois Bolko, Wei Jiang, Nozomu Tawara, Oceane Landon-Cardinal, Celine Anquetil, Olivier Benveniste, Yves Allenbach
Summary: The classification of idiopathic inflammatory myopathies is based on clinical, serological, and histological criteria. The identification of myositis-specific antibodies has helped to define more homogeneous groups of myositis into four dominant subsets, each with distinct pathophysiological mechanisms. Additionally, interferon pathways have been identified as key players in the pathophysiology of myositis, with different types of interferons playing specific roles in each subset.
Article
Energy & Fuels
Yufu Han, Mareike Noah, Volker Luders, Sandor Kormos, Felix Schubert, Stefanie Poetz, Brian Horsfield, Kai Mangelsdorf
Summary: This study investigates the fractionation of organic compounds in fluid inclusions and source rock extracts, and finds that molecular polarity, size, and aromaticity are the most important factors affecting the migration and retention behavior of petroleum hydrocarbons and NSO compounds.
INTERNATIONAL JOURNAL OF COAL GEOLOGY
(2022)
Article
Energy & Fuels
Kang Li, Zhongfeng Zhao, Hong Lu, Xinran Liu, Ping'an Peng, Chang Samuel Hsu
Summary: This study investigated the effect of inherent pyrite on hydrocarbon generation of kerogen through a series of experiments. The presence of pyrite in kerogen resulted in lower yield of liquid hydrocarbons and higher peak temperature for liquid hydrocarbon production. In addition, the thermal transformation of pyrite decreased the wet gas yield and increased the iso- to normal paraffin ratios.
Article
Geosciences, Multidisciplinary
Yoav O. Rosenberg, Itay J. Reznik, Harold J. Vinegar, Shimon Feinstein, Yuval Bartov
Summary: This study explores the natural thermal maturation of sulfur-rich Type II-S source rocks, comparing geochemical data from the Golan Basin with an artificial maturation experiment in the Shfela Basin. The research suggests that sulfur content may affect hydrocarbon generation and contribute to differences in maturation paths between different kerogens.
MARINE AND PETROLEUM GEOLOGY
(2021)
Article
Chemistry, Medicinal
Thomas Hanke, Sebastian Mathea, Julia Woortman, Eidarus Salah, Benedict-Tilman Berger, Anthony Tumber, Risa Kashima, Akiko Hata, Bernhard Kuster, Susanne Mueller, Stefan Knapp
Summary: In this study, three highly selective LIMK1/2 inhibitors were characterized, providing potential candidate drugs for the treatment of diseases associated with LIMK dysregulation.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Energy & Fuels
Deping Zhang, Huairen Cao, Yan Lei, Hao Wu, Xiaoyu Wang, Xuelian Guo, Jianping Yan, Shuhua Wang, Tianchi Shi, Haolin Li, Yan-rong Zou, Ping'an Peng
Summary: This study simulated the maturation process of lacustrine type II kerogen and investigated the molecular structure evolution. It was found that the aliphatic fractions decreased and aromatic fractions increased with increasing maturity. Before the main oil window, nonhydrocarbon heteroatomic functional groups were the main products. The oil peak occurred when hydrocarbon C14+ production reached its maximum. After the oil peak, aromatic groups became dominant. In the gas window, the large quantity of C1-5 was mainly due to the secondary cracking of hydrocarbons. The number of aromatic structures caused by alkyl bond breaking and condensation was estimated.
Review
Immunology
Elena Cabezon, Fernando Valenzuela-Gomez, Ignacio Arechaga
Summary: This article discusses the mechanisms and structural and functional similarities between Type III and Type IV protein secretion systems in pathogens. The correlation between the structure and function of essential components in these systems provides significant insights into the development of inhibitors that can effectively target these systems.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Samara R. Alves, Rodrigo L. S. R. Santos, Barbara Fornaciari, Alison Colquhoun, Denise de Oliveira Silva
Summary: The interaction of diruthenium metal-metal multiply bonded paddlewheel complexes bearing non-steroidal anti-inflammatory drugs with 4-aminopyridine drug was studied, resulting in the successful synthesis of a novel metallodrug with anticancer activity.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Energy & Fuels
Y. Zhou, Z. G. Xu, Z. H. Wu
Summary: This study investigates the formation mechanism of hydrogen sulfide during the pyrolysis process of Chang 7 type-II oil shale kerogen. XPS spectra were obtained to analyze the forms of hybrid atoms, and the pyrolysis characteristics were studied using ReaxFF. The sulfur element in the kerogen was mainly in the form of organic sulfur, and the desulfurization rate increased with higher pyrolysis temperatures. Hydrogen sulfide production was influenced by various sulfur-containing functional groups.
Article
Energy & Fuels
Hong Wu, Long Wen, Li Zhang, Dongbo Wang, Nong Li, Mingli Yang
Summary: The pore structures and methane adsorption of different maturity kerogens at varying burial depths were studied using molecular dynamics and grand canonical Monte Carlo simulations. The results show that methane adsorption capacity varies with kerogen maturity and burial depth, and there is a mismatch between surface structure evolution and pore change in kerogens.
Article
Energy & Fuels
Xiaowei Zheng, Hamed Sanei, Niels H. Schovsbo, Qingyong Luo, Jia Wu, Ningning Zhong, Jennifer M. Galloway, Fariborz Goodarzi
Summary: This study investigated the impact of zooclasts on the organic matter composition, kerogen type, and hydrocarbon generation potential of the Alum shale. Results showed that graptolite granular fraction and diagenetic solid bitumen have similar optical characteristics and hydrocarbon generation potential. The enrichment of zooclastic cuticle affects the organic carbon composition and leads to underestimation of the Hydrocarbon Index (HI). The difference in hydrocarbon generation potential between zooclastic cuticle-lean and zooclastic cuticle-rich samples is attributed to variations in organic constituent composition.
INTERNATIONAL JOURNAL OF COAL GEOLOGY
(2021)
Article
Chemistry, Physical
Romain Vollondat, Stephane Roques, Celine Chevalier, Jeremy Bartringer, Jean-Luc Rehspringer, Abdelilah Slaoui, Thomas Fix
Summary: Type I (Na8Si46) or type II (Nax <= 24Si136) silicon clathrates films with a large surface area have been synthesized using a two-step process. The specific type of silicon clathrates phase can be selectively obtained by finely tuning the synthesis conditions. These films demonstrate higher optical absorption coefficients compared to diamond silicon in the visible light range, with type II films showing a direct bandgap suitable for photovoltaic applications. The surface defects and inhomogeneities of the as-prepared type II films have been significantly reduced through pressure annealing treatment.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)