Article
Chemistry, Multidisciplinary
Wachara Benchaphanthawee, Chi-How Peng
Summary: Cobalt mediated radical polymerization (CMRP) plays a crucial role in controlling the polymerization of less active monomers, such as vinyl acetate, with the control mechanisms being correlated to the redox potential of cobalt complexes. The hybridization of CMRP and atom transfer radical polymerization (ATRP) allows for the direct synthesis of block copolymers in one pot. CMRP also enables the control of isotacticities and crystalline properties in polymers.
Article
Polymer Science
Hanyu Lv, Jiaqi An, Fanfan Li, Yanwu Zhang
Summary: Reversible deactivation radical polymerization (RDRP) is a convenient and efficient technique for synthesizing polymers with precise structure. dl-Methionine is assessed as a control agent in RDRP of styrene and methyl methacrylate, effectively reducing polymer dispersity. The use of dl-Methionine allows for high end fidelities in the synthesis of polymethyl methacrylate-block-polystyrene.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Ruoyu Li, Weina Kong, Zesheng An
Summary: This Minireview discusses the key roles enzymes play in reversible deactivation radical polymerization (Enz-RDRP) and highlights their applications in surface brush fabrication, sensing, polymerization-induced self-assembly, and high-throughput synthesis. The authors also reflect on the challenges and future directions of this emerging area.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Polymer Science
Graeme Moad
Summary: This paper discusses the development of the term 'reversible-deactivation radical polymerization (RDRP)' and highlights the significance of the paper that introduced this term.
POLYMER INTERNATIONAL
(2023)
Review
Chemistry, Applied
Sharmaine B. Luk, Lorena A. Azevedo, Milan Maric
Summary: Dienes such as isoprene and butadiene are commonly used to give rubbery properties to polymeric materials. With a shift towards using renewable resources, bio-based monomers have been targeted as replacements for petroleum-based dienes in polymer production. Recent advancements in reversible deactivation radical polymerization (RDRP) have enabled the application of bio-based dienes in making polymeric materials with controlled microstructures and chain lengths.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Review
Chemistry, Multidisciplinary
Ali Bagheri, Christopher M. Fellows, Cyrille Boyer
Summary: 3D printing technology has revolutionized the fabrication of advanced materials, but the challenge remains in printing polymer materials with post-printing transformability. Traditional radical polymerization used in photopolymerization-based 3D printing offers limited control over chain growth and architecture, unlike the reversible deactivation radical polymerization which allows for network homogeneity tuning and the production of reactivatable species for subsequent processes. RDRP-based networks have advantages over conventionally formed networks in terms of controllability and post-synthetic transformations.
Review
Chemistry, Multidisciplinary
Zilong Wu, Cyrille Boyer
Summary: Near-infrared (NIR) light-induced reversible deactivation radical polymerization (NIR-RDRP) is an effective technique for preparing functional polymer materials using light energy. This review comprehensively summarizes the mechanisms and applications of NIR-RDRP systems.
Article
Polymer Science
Jin-Ying Wang, Yuan-Yuan Ni, Jian-Nan Cheng, Li-Fen Zhang, Zhen-Ping Cheng
Summary: The article introduces a strategy combining RCMP and SET-DTLRP to adjust the dispersity of polymers, successfully preparing a block copolymer with adjustable dispersity.
CHINESE JOURNAL OF POLYMER SCIENCE
(2021)
Review
Chemistry, Organic
Ze-Le Chen, Yang Xie, Jun Xuan
Summary: Cyclopropanes are important strained rings widely used in pharmaceuticals and natural product synthesis. Photochemical cyclopropanation has emerged as a robust method for preparing diverse cyclopropane backbones. This review summarizes recent advances in visible light-mediated cyclopropane synthesis, focusing on carbene transfer strategy and photocatalytic radical cyclopropanation reactions.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Polymer Science
Fehaid M. Alsubaie, Othman Y. Alothman, Hassan Fouad, Abdel-Hamid I. Mourad
Summary: This study reported the aqueous Cu(0)-mediated reversible deactivation radical polymerization (RDRP) of triblock copolymers with two block sequences at 0.0 degrees C. Sequence-controlled triblock copolymers were successfully synthesized via ultrafast one-pot synthesis and without any purification steps throughout the monomer additions. The resulting copolymers exhibited narrow dispersities, controlled chain length, and quantitative conversion.
Review
Materials Science, Multidisciplinary
Valentin A. Bobrin, Jin Zhang, Nathaniel Corrigan, Cyrille Boyer
Summary: The majority of materials used in vat photopolymerization 3D printing are effectively dead materials as they cannot be easily modified. However, the development of photocontrolled reversible-deactivation radical polymerization (photoRDRP) techniques in 3D printing has provided access to advanced materials with properties such as on-demand editing, self-healing, and control over nanostructuration and mechanical properties.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Chemistry, Physical
Jiapian Huang, Zhiyuan Chen, Jie Wu
Summary: Methylation is a crucial process in biology, and radical-type methylation protocols have been developed for late-stage modifications of privileged scaffolds in pharmaceutical research. The chemistry involving methyl-radical-involved conversions has significantly developed in recent years. Various pathways for methyl radical generation have been explored, including photo-/electro-catalysis, transition-metal catalysis, transition-metal-free methylations, and demethylation-triggered radical cyclization/cascade reactions. Representative methyl-containing molecules produced from these reactions have been analyzed.
Article
Chemistry, Applied
Bin Peng, Xiaoling Xu, Yan Wang, Jingyu Zhang, Jing Chen, Qiang Zhang
Summary: A branched polymer coating was successfully synthesized via copper-based reversible deactivation radical polymerization and applied to membrane surfaces, resulting in improved fouling resistance and stability.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Polymer Science
Shuaiyuan Han, Yichao Zheng, Jit Sarkar, Hiroshi Niino, Shunsuke Chatani, Atsushi Goto
Summary: This paper reports the first use of organic chloride salts as catalysts for reversible complexation mediated living radical polymerization. The chloride salt catalysts have wide monomer scope, good livingness, accessibility to block copolymers, and good solubility in organic media. Therefore, the use of chloride salt catalysts is industrially attractive and may lower the cost of polymerization.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Polymer Science
Weijia Mao, Xiu Ting Tay, Jit Sarkar, Chen-Gang Wang, Atsushi Goto
Summary: An air-tolerant reversible complexation mediated polymerization (RCMP) technique has been developed, which does not require deoxygenation. The technique uses aldehyde, N-hydroxyphthalimide (NHPI), and a base as catalysts. The oxygen in the system is consumed through NHPI-catalyzed conversion to carboxylic acid, which is then converted to carboxylate anion by the base. This technique is applicable to various monomers and produces polymers with low dispersity.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Faiza Diaba, Gisela Trenchs
Summary: The first violet light-mediated synthesis of gamma- and delta-lactams from N-alkenyl trichloroacetamides is reported in this paper. The reactions are conducted in tetrahydrofuran or 2-methyltetrahydrofuran as the sole solvent without catalysts or additives, under non-anhydrous conditions in an air atmosphere where the solvent serves as the radical initiator.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Feroze Hussain, Sajjad Ahmed, Ashiq Hussain Padder, Qazi Naveed Ahmed
Summary: This study reports a novel and efficient one-pot synthesis method for mixed phosphorotrithioates, which does not require supplementary additives and shows broad applicability.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Hyunjin Oh, Ikyon Kim
Summary: A new 1,2,4-triazole-pyrrolo[1,2-a]pyrazine hybrid system, 6-acylpyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, was synthesized using a catalyst-free method. This method involved sequential exposure of pyrrole-2-carbonitrile-derived substrates to DMF-DMA and acyl hydrazide, resulting in the formation of acylated pyrazine and 1,2,4-triazole rings, enabling the installation of various substituents at specific positions on the core skeleton.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Ming Yan, Si-fan Wang, Yong-po Zhang, Jin-zhong Zhao, Zhuo Tang, Guang-xun Li
Summary: Here we developed an efficient photocatalytic approach for the convenient preparation of sulfinamides. The reaction allows for the gram-scale preparation of sulfinamides and the one-pot synthesis of various sulfonyl amides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Farzaneh Bandehali-Naeini, Zahra Tanbakouchian, Noushin Farajinia-Lehi, Nicolas Mayer, Morteza Shiri, Martin Breugst
Summary: Two tandem catalytic systems were developed for the synthesis of novel 3,4-disubstituted maleimides using the same Ugi adducts. Different maleimide structures can be synthesized using either Pd or Cu catalysis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Tanya Raghava, Anjan Chattopadhyay, Subhadeep Banerjee, Nivedita Sarkar
Summary: Amine substitution of two ortho fluorine atoms of tetrafluoroterephthalonitrile through SNAr chemistry is easily achievable. But further fluorine substitution is only possible under forcing conditions, yielding valuable fluorophores for bioimaging.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Review
Chemistry, Organic
Anju Chadha, Santosh Kumar Padhi, Selvaraj Stella, Sowmyalakshmi Venkataraman, Thangavelu Saravanan
Summary: Alcohol dehydrogenases are enzymes that use cofactors for oxidation or reduction reactions of alcohols or carbonyl compounds. They are utilized in green chemistry and have applications in the production of pharmaceuticals. Recombinant enzymes have solved the challenge of producing purified enzymes in large quantities. Engineered alcohol dehydrogenases have been used in asymmetric synthesis in industry. Various methods have been established for regenerating expensive cofactors to make the enzymatic process more efficient and economically viable.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)