Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 48, Pages 9881-9886Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ob02035a
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Funding
- National Natural Science Foundation of China
- Ministry of Science and Technology [2010CB833305, 2011CB808600]
- Chinese Academy of Sciences
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An efficient cooperative biscinchona alkaloid and Lewis acid catalytic system was developed in the enantioselective alpha-alkylation of 2-oxindoles with (3-indolyl)(phenyl)methanols to provide (2-oxindole)-linker-indole derivatives in good yields (70-83%) with high enantioselectivities (81%-92%).
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