Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 12, Issue 3, Pages 414-417Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob42037j
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Funding
- National Program on Key Basic Research Project of China (973 Program) [2013CB328900]
- National Science Foundation of China [21202107]
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An efficient method for the oxidative amidation of benzylic aldehydes or alcohols with ammonium salts has been developed for the synthesis of primary amides using Et4NI as the catalyst and tert-butyl hydroperoxide as the oxidant. This amidation reaction is operationally straightforward and provides primary amides in moderate to good yields under mild conditions.
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