Asthma-COPD overlap 2015: now we are six

Heterogeneity of Bronchitis in Airway Diseases in Tertiary Care Clinical Practice

(2016) Liesel D’silva et al.   Canadian Respiratory Journal

Biological clustering supports both “Dutch” and “British” hypotheses of asthma and chronic obstructive pulmonary disease

(2015) Michael A. Ghebre et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Why is COPD phenotyping like sorting diamonds?

(2014) P. G. Gibson et al.   EUROPEAN RESPIRATORY JOURNAL

The clinical and genetic features of COPD-asthma overlap syndrome

(2014) M. Hardin et al.   EUROPEAN RESPIRATORY JOURNAL

Eosinophilic inflammation in COPD: prevalence and clinical characteristics: Table 1–

(2014) Dave Singh et al.   EUROPEAN RESPIRATORY JOURNAL

Generic utilities in chronic obstructive pulmonary disease patients stratified according to different staging systems

(2014) Marc Miravitlles et al.   Health and Quality of Life Outcomes

Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease

(2014) Andrea S. Gershon et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prognostic value of cluster analysis of severe asthma phenotypes

(2014) Arnaud Bourdin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

(2014) Wei Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical Significance of Asthma Clusters by Longitudinal Analysis in Korean Asthma Cohort

(2014) So Young Park et al.   PLoS One

Statistical Cluster Analysis of the British Thoracic Society Severe Refractory Asthma Registry: Clinical Outcomes and Phenotype Stability

(2014) Chris Newby et al.   PLoS One

Stepwise withdrawal of inhaled corticosteroids in COPD patients receiving dual bronchodilation: WISDOM study design and rationale

(2014) Helgo Magnussen et al.   RESPIRATORY MEDICINE

Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema

(2014) Peter J Castaldi et al.   THORAX

The association between childhood asthma and adult chronic obstructive pulmonary disease

(2014) Andrew Tai et al.   THORAX

Systemic Inflammation in Older Adults With Asthma-COPD Overlap Syndrome

(2014) Juan-juan Fu et al.   Allergy Asthma & Immunology Research

Risk of pneumonia with inhaled corticosteroid/long-acting β2 agonist therapy in chronic obstructive pulmonary disease: a cluster analysis

(2014) Rachael DiSantostefano et al.   International Journal of Chronic Obstructive Pulmonary Disease

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study

(2014) Christopher E Brightling et al.   Lancet Respiratory Medicine

Ten-Year Follow-up of Cluster-based Asthma Phenotypes in Adults. A Pooled Analysis of Three Cohorts

(2013) Anne Boudier et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased Risk of Exacerbation and Hospitalization in Subjects With an Overlap Phenotype

(2013) Ana Maria B. Menezes et al.   CHEST

Subphenotypes of Mild-to-Moderate COPD by Factor and Cluster Analysis of Pulmonary Function, CT Imaging and Breathomics in a Population-Based Survey

(2013) Niki Fens et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Medical Utilization and Cost in Patients with Overlap Syndrome of Chronic Obstructive Pulmonary Disease and Asthma

(2013) Chin Kook Rhee et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap

(2013) H. Iwamoto et al.   EUROPEAN RESPIRATORY JOURNAL

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis

(2013) Wendy C. Moore et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Childhood asthma clusters and response to therapy in clinical trials

(2013) Timothy S. Chang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cluster analysis identifies characteristic phenotypes of asthma with accelerated lung function decline

(2013) Takuro Sakagami et al.   JOURNAL OF ASTHMA

β-Blockers and Chronic Obstructive Pulmonary Disease: Inappropriate Avoidance?

(2013) Deborah S. Minor et al.   Journal of Clinical Hypertension

The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD): Prevalence and Risk Factors in Young, Middle-aged and Elderly People from the General Population

(2013) Roberto de Marco et al.   PLoS One

Longitudinal Changes in Clinical Outcomes in Older Patients with Asthma, COPD and Asthma-COPD Overlap Syndrome

(2013) Juan-juan Fu et al.   RESPIRATION

What Proportion of Chronic Obstructive Pulmonary Disease Outpatients Is Eligible for Inclusion in Randomized Clinical Trials?

(2013) Nicola Scichilone et al.   RESPIRATION

Characterisation of the overlap COPD–asthma phenotype. Focus on physical activity and health status

(2013) Marc Miravitlles et al.   RESPIRATORY MEDICINE

Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms?

(2013) Lowie E G W Vanfleteren et al.   THORAX

Multidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense?

(2013) Vanessa M McDonald et al.   THORAX

Which patients with chronic obstructive pulmonary disease benefit from the addition of an inhaled corticosteroid to their bronchodilator? A cluster analysis

(2013) Rachael L DiSantostefano et al.   BMJ Open

Integrated care model with self-management in chronic obstructive pulmonary disease

(2013) Jean Bourbeau et al.   Chronic Respiratory Disease

The Interplay between the Effects of Lifetime Asthma, Smoking, and Atopy on Fixed Airflow Obstruction in Middle Age

(2012) Jennifer L. Perret et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dietary restriction and exercise improve airway inflammation and clinical outcomes in overweight and obese asthma: a randomized trial

(2012) H. A. Scott et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Exacerbations of severe asthma

(2012) V. M. McDonald et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Managing Older Patients with Coexistent Asthma and Chronic Obstructive Pulmonary Disease

(2012) Vanessa M. McDonald et al.   DRUGS & AGING

Identification of asthma clusters in two independent Korean adult asthma cohorts

(2012) Tae-Bum Kim et al.   EUROPEAN RESPIRATORY JOURNAL

Identification of Subtypes of Refractory Asthma in Korean Patients by Cluster Analysis

(2012) An Soo Jang et al.   LUNG

Cluster Analysis of Obesity and Asthma Phenotypes

(2012) E. Rand Sutherland et al.   PLoS One

Application of the Asthma Phenotype Algorithm from the Severe Asthma Research Program to an Urban Population

(2012) Paru Patrawalla et al.   PLoS One

Early origins of chronic obstructive pulmonary disease

(2012) Indra Narang et al.   Seminars in Fetal & Neonatal Medicine

The COPD control panel: towards personalised medicine in COPD

(2012) Alvar Agusti et al.   THORAX

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

(2012) Paul Albert et al.   THORAX

Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2011) Mona Bafadhel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Physical Activity Is the Strongest Predictor of All-Cause Mortality in Patients With COPD

(2011) Benjamin Waschki et al.   CHEST

Asthma, Chronic Obstructive Pulmonary Disease, and Mortality in the U.S. Population

(2011) Enrique Diaz-Guzman et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Patterns of airway disease and the clinical diagnosis of asthma in the Busselton population

(2011) A. W. Musk et al.   EUROPEAN RESPIRATORY JOURNAL

Identifying adult asthma phenotypes using a clustering approach

(2011) V. Siroux et al.   EUROPEAN RESPIRATORY JOURNAL

Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program

(2011) Anne M. Fitzpatrick et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Multidimensional assessment of older people with asthma and COPD: clinical management and health status

(2010) V. M. McDonald et al.   AGE AND AGEING

Chronic Obstructive Pulmonary Disease Phenotypes

(2010) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Use of cluster analysis to define COPD phenotypes

(2010) M. Weatherall et al.   EUROPEAN RESPIRATORY JOURNAL

Asthma in older adults

(2010) Peter G Gibson et al.   LANCET

Improvements in Symptoms and Quality of Life following Exercise Training in Older Adults with Moderate/Severe Persistent Asthma

(2010) Sian Turner et al.   RESPIRATION

Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes

(2010) J. Garcia-Aymerich et al.   THORAX

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes

(2010) S. Gupta et al.   THORAX

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The definition and diagnosis of Asthma

(2009) F. E. Hargreave et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Systemic manifestations and comorbidities of COPD

(2009) P. J. Barnes et al.   EUROPEAN RESPIRATORY JOURNAL

Distinct clinical phenotypes of airways disease defined by cluster analysis

(2009) M. Weatherall et al.   EUROPEAN RESPIRATORY JOURNAL

The overlap syndrome of asthma and COPD: what are its features and how important is it?

(2009) P G Gibson et al.   THORAX

Early life origins of chronic obstructive pulmonary disease

(2009) C Svanes et al.   THORAX

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of Pharmacotherapy on Rate of Decline of Lung Function in Chronic Obstructive Pulmonary Disease

(2008) Bartolomé R. Celli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE