A computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2

Formation of a Covalent Glycosyl-Enzyme Species in a Retaining Glycosyltransferase

(2013) Víctor Rojas-Cervellera et al.   CHEMISTRY-A EUROPEAN JOURNAL

Substrate-Assisted and Nucleophilically Assisted Catalysis in Bovine α1,3-Galactosyltransferase. Mechanistic Implications for Retaining Glycosyltransferases

(2013) Hansel Gómez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Geometric Attributes of Retaining Glycosyltransferase Enzymes Favor an Orthogonal Mechanism

(2013) Brock Schuman et al.   PLoS One

Site-specific protein O-glycosylation modulates proprotein processing — Deciphering specific functions of the large polypeptide GalNAc-transferase gene family

(2012) Katrine T.-B.G. Schjoldager et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Essential role of glutamate 317 in galactosyl transfer by α3GalT: a computational study

(2012) Hansel Gómez et al.   CARBOHYDRATE RESEARCH

Substrate-Assisted Catalytic Mechanism of O-GlcNAc Transferase Discovered by Quantum Mechanics/Molecular Mechanics Investigation

(2012) Igor Tvaroška et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Retaining Glycosyltransferase Mechanism Studied by QM/MM Methods: Lipopolysaccharyl-α-1,4-galactosyltransferase C Transfers α-Galactose via an Oxocarbenium Ion-like Transition State

(2012) Hansel Gómez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Molecular Mechanism of Enzymatic Glycosyl Transfer with Retention of Configuration: Evidence for a Short-Lived Oxocarbenium-Like Species

(2011) Albert Ardèvol et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase

(2011) Seung Seo Lee et al.   Nature Chemical Biology

Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors

(2010) James C. Errey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trapping and characterization of covalent intermediates of mutant retaining glycosyltransferases

(2010) Naoto Soya et al.   GLYCOBIOLOGY

Evaluation of Density Functionals and Basis Sets for Carbohydrates

(2009) Gábor I. Csonka et al.   Journal of Chemical Theory and Computation

QM/MM simulations predict a covalent intermediate in the hen egg white lysozyme reaction with its natural substrate

(2008) Anna L. Bowman et al.   CHEMICAL COMMUNICATIONS

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH

Glycosyltransferases: Structures, Functions, and Mechanisms

(2007) L.L. Lairson et al.   Annual Review of Biochemistry