Article
Chemistry, Multidisciplinary
Yufeng Cao, Yanmei Chen, Zhecheng Zhang, Jin Wang, Xiaolei Yuan, Qin Zhao, Yue Ding, Yong Yao
Summary: A new supramolecular amphiphile was constructed based on water soluble pillar[5]arene and a unique guest with CO2 responsive and UV responsive properties. The self-assembly process formed various structures under different conditions, offering potential for on demand drug absorption and release. The study was characterized using TEM, SEM, DLS, SAXS, and NMR technologies.
CHINESE CHEMICAL LETTERS
(2021)
Article
Polymer Science
Daniel J. Whitaker, Junsu Park, Chiharu Ueda, Guanglu Wu, Akira Harada, Go Matsuba, Yoshinori Takashima, Oren A. Scherman
Summary: The amount of water in a material is important for understanding its mechanical properties, especially in biological materials. Studying a simple hydrogel model system can provide insights into complex natural materials. The size of the cap and the water content in the hydrogel affect its mechanical properties, and the influence of water content and complex formation on the tensile properties of the hydrogel depends on the size of the cap. Small angle X-ray scattering reveals that the homogeneity of the hydrogel depends on the water content, while the formation of distinct domains depends on the size of the cap.
Article
Chemistry, Multidisciplinary
Xiao Xiao, Zhirui Xu, Wenkai Wang, Siyuan Sun, Yan Qiao, Lingxiang Jiang, Yun Yan, Jianbin Huang
Summary: A versatile supramolecular platform was reported to construct enzyme-responsive nanosystems via host-guest interactions, leading to the formation of various nanostructures capable of actively releasing water-soluble molecules or functional nanoparticles in the presence of alpha-amylase.
Article
Chemistry, Organic
Xiaodong Zhang, Tao Sun, Xin-Long Ni
Summary: This study explores the host-guest interactions of cucurbit[8]uril with pi-conjugated bispyridinium guests in aqueous solution, resulting in a series of dynamic assemblies distinguishable by naked-eye observation and quantitative fluorescence emissions. The dissociation and control of host-stabilized charge-transfer interactions by N-substituted alkyl chains on cationic guests led to the discovery of new possible binding modes for the cucurbit[8]uril host.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Agnieszka Jedrych, Mateusz Pawlak, Ewa Gorecka, Wiktor Lewandowski, Michal Maksymilian Wojcik
Summary: We have demonstrated the fabrication of dual-responsive (thermo/light) chiral plasmonic films by using photoswitchable achiral liquid crystal (LCs) for templating helical assemblies of Au NPs. The chiroptical properties of the organic and inorganic components were confirmed by circular dichroism spectroscopy (CD), with a dissymmetry factor (g-factor) of up to 0.2. The controlled melting of organic nanotubes and/or inorganic nanohelices can be achieved by exposing the material to UV light and can be reversed using visible light, with the chiroptical response further modified by varying the temperature.
Article
Chemistry, Multidisciplinary
Dong Wang, Zhihao Fan, Xuecheng Zhang, Hui Li, Yawei Sun, Meiwen Cao, Guangcheng Wei, Jiqian Wang
Summary: A novel anticancer prodrug molecule was designed for targeted drug delivery, which could self-assemble into different nanostructures at different pH levels. The self-assemblies demonstrated good cancer cell selectivity, mainly due to their pH-responsive structural transition and folate active targeting effect.
Article
Chemistry, Multidisciplinary
Aries Kwok-Heung Chan, Ming-Hin Chau, Yikun Ren, Jia-Jun Jiang, Man-Kin Wong, Franco King-Chi Leung
Summary: Gold (III) cyclometalated based amphiphiles in aqueous media exhibit excellent supramolecular transformations, providing new pathways for the fabrication of soft functional materials. A new chiral cyclometalated gold (III) amphiphile (GA) was reported, which forms lamellar nanostructures in aqueous media as confirmed by transmission electron microscopy (TEM). Counterion exchange with D-, L-, or racemic-camphorsulfonates enhances the supramolecular helicity of GA, leading to transformations from lamellar structure to vesicles and nanotubes with multiple equivalents of counterion. The limited cytotoxicity of GA in aqueous media demonstrates good biocompatibility.
Article
Chemistry, Multidisciplinary
Shanshan Wang, Zhe Huang, Anyang Li, Yanxia Zhao, Wei Zuo, Yawen Li, Haohao Miao, Jiacheng Ma, Wei Sun, Xiaoqing Wang, Liping Cao, Biao Wu, Chuandong Jia
Summary: This study reports a cascaded guest delivery between two anionocages, where binding of K+ ions triggers the release and delivery of another guest, and elimination of K+ enables reversed guest delivery. Integrative self-sorting of anionocages is achieved for the first time, leading to enhanced guest binding affinities in heteroleptic cages.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Hiromitsu Maeda, Yohei Haketa, Tomoki Murata, Eriko Ohta, Tai Murata, Nobuhiro Yasuda
Summary: Introducing carboxy units onto dipyrrolyldiketone skeletons by complexation with arylfluoroboron moieties bearing an acid group results in formation of anion-binding self-assemblies, leading to ion-pairing assemblies.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Dan Wu, Peng-Feng Zhang, Guo-Ping Yang, Lei Hou, Wen-Yan Zhang, Ying-Feng Han, Ping Liu, Yao-Yu Wang
Summary: This review explores the influence of MOF pore properties on the capture and separation of tailored guest molecules, presenting specific strategies to enhance adsorption/separation performance and discussing supramolecular interactions between adsorbates and adsorbents. The applications of porous MOF materials in adsorption/separation are also discussed and further prospects are provided.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Jianan Zhang, Xueting Lu, Wen Li, Afang Zhang
Summary: This study reports the supramolecular chiral assembly of amphiphilic dendronized tetraphenylethylenes in aqueous solutions. The supramolecular aggregates exhibited thermoresponsive behavior and aggregation-induced fluorescent emission, which could be reversibly tuned by temperature and pH conditions.
Article
Chemistry, Multidisciplinary
Oleksandr Zagorodko, Tetiana Melnyk, Vicent J. Nebot, Patricia Y. W. Dankers, Maria J. Vicent
Summary: In this study, a novel patterned cross-beta structure formed by self-assembled peptide amphiphiles based on diphenylalanine and benzene-1,3,5-tricarboxamide (BTA) is reported. The incorporation of topological constraints on one edge of the diphenylalanine fragment leads to the formation of an unconventional offset-patterned cross-beta structure. Two patterned cross-beta structures bind parallel arrays of BTA stacks in a superstructure within a single-molecule-thick nanoribbon. These findings provide a simple approach to incorporating novel patterned cross-beta motifs into supramolecular superstructures and shed light on the general mechanism of beta-sheet formation in C-3-symmetric peptide amphiphiles.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Review
Chemistry, Physical
Nina Qian, Xiao-Fang Hou, Yuqi Tang, Shu Zhang, Xu-Man Chen, Quan Li
Summary: Supramolecular luminescent nano-assemblies for cell imaging have gained increasing interest for their excellent photophysical properties, easy fabrication, biocompatibility, stability, and combination with synergistic therapy. Luminescence-based bioimaging has advantages such as high sensitivity, non-invasiveness, and real-time functionality, making it widely applied in various fields. This review focuses on the recent progress in macrocycle-mediated and functionalized amphiphilic molecule-based supramolecular luminescent nanoparticles, specifically regarding targeted cell imaging and the combination with drug delivery, gene delivery, and photodynamic therapy.
Article
Materials Science, Multidisciplinary
Ying Zhang, Zhuoran Xu, Tao Jiang, Yanyan Fu, Xiang Ma
Summary: Developing visible real-time monitoring methods for kinetic traps in thermodynamic equilibrium processes is essential in dynamic supramolecular chemistry research. In this study, a dynamic supramolecular system was designed and fabricated using host-guest interactions between pyrene derivatives (Py-TMA) and p-sulfonatocalix[4]arenes (SC4) in aqueous solution. The emission color of Py-TMA changed spontaneously from indigo blue to cyan after assembly with SC4, and gradually returned to the original indigo blue within 72 hours. The research demonstrated that this optical variation involved an excimer on/off process in a kinetic-trapped state. Additionally, a dynamic and time-variant artificial-light-harvesting system was successfully fabricated, showing a red-to-blue emission color change with an energy transfer efficiency of up to 99%.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Feihong Lu, Yi Chen, Boqiao Fu, Shigui Chen, Lu Wang
Summary: A stimuli-responsive supramolecular polymer network has been created using host-guest interactions, and its dissociation through the addition of competitive molecules and heating results in significant changes in its physical properties.
CHINESE CHEMICAL LETTERS
(2022)
Review
Engineering, Environmental
Caiyan Yue, Long Chen, Heng Zhang, Jinshu Huang, Hao Jiang, Hu Li, Song Yang
Summary: Water pollution is a pressing global environmental issue due to the presence of toxic organic pollutants. Photocatalysis, particularly using metal-organic frameworks (MOFs), has shown great promise for organic pollutant removal in wastewater treatment. This review summarizes recent advances in MOF-based photocatalysts, including preparation strategies, modification techniques, and applications for organic pollutant degradation. The working mechanisms, heterojunctions, and key parameters affecting the photocatalytic degradation process are also discussed. The future outlook and challenges of MOF materials for removing organic pollutants from water are emphasized.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Yujiao Zhang, Zhao Hu, Heng Zhang, Hu Li, Song Yang
Summary: A novel Covalent organic skeleton/metal oxide (COF/MOx) Z scheme heterojunction was constructed for selective oxidation of nitric oxide (NO). The optimized COF/TiO2 catalyst exhibited excellent NO removal rate (64.5%) under visible-light irradiation due to improved light absorption, efficient separation of photoexcited electron-hole pairs, and activation of O-2 by uniform COF coating. The selectivity towards nitrate (NO3-) was improved to 99.9% by enhancing the generation of superoxide radicals as the main reactive species and limiting the production of intermediate nitrogen dioxide (NO2). This study demonstrates the potential of the Z scheme heterojunction for universal applications.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Zhengyi Li, Peng Zhou, Min Zhou, Hao Jiang, Hu Li, Shengqi Liu, Heng Zhang, Song Yang, Zehui Zhang
Summary: In this study, a new bifunctional indium hydroxide material was developed for the high-efficiency synthesis of urea from CO2 and nitrogenous pollutants. The material, with dual active sites and facet and defect engineering, showed selective catalytic activity for the conversion of CO2 and NO3-, leading to improved urea synthesis efficiency.
APPLIED CATALYSIS B-ENVIRONMENT AND ENERGY
(2023)
Article
Engineering, Environmental
Hongmei Xiang, Jiao Meng, Wubin Shao, Dan Zeng, Jin Ji, Peiyi Wang, Xiang Zhou, Puying Qi, Liwei Liu, Song Yang
Summary: The excessive use and eco-unfriendly behavior of traditional pesticide formulations have serious drawbacks. In this study, a scalable and sustainable biopolymer-based core-shell nanocarrier loaded with an anti-viral candidate agent was developed for plant disease management. The nanocarrier exhibited enhanced UV resistance, improved foliar surface wettability, and activated host plant defense responses.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Agronomy
Jiao-Jiao Zhang, Yu-Mei Feng, Jun-Rong Zhang, Wan-Lin Xiao, Shuai-Shuai Liu, Xiang Zhou, Heng Zhang, Pei-Yi Wang, Li-Wei Liu, Song Yang
Summary: A series of simple triclosan derivatives containing isopropanolamine moiety were designed and assessed for their antibacterial behavior. Some compounds showed excellent bioactivity against three destructive bacteria. Compound C-8 displayed high bioactivities towards Xoo and Xac.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Zhenxing Li, Binxin Yang, Yue Ding, Xiang Zhou, Zimian Fang, ShuaiShuai Liu, Jie Yang, Song Yang
Summary: A series of phosphonate derivatives containing a 1,2,3-triazole motif were developed and evaluated for their antiviral activity against tobacco mosaic virus (TMV) helicase. The optimized B-17 showed stronger curative activity against TMV compared to the commercial drug Ribavirin. Additionally, B-17 exhibited potential antiviral activity against other viruses and pathogens.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Bin-Xin Yang, Zhen-Xing Li, Shuai-Shuai Liu, Jie Yang, Pei-Yi Wang, Hong-Wu Liu, Xiang Zhou, Li-Wei Liu, Zhi-Bing Wu, Song Yang
Summary: Two series of novel cinnamic acid derivatives were designed and synthesized to explore alternative agrochemicals for controlling plant virus and bacterial diseases. The bioassay results showed that these derivatives exhibited excellent antiviral competence, with compound A(5) demonstrating remarkable protective effects against tobacco mosaic virus. This research provides a foundation for the practical application of cinnamic acid derivatives in pesticide exploration.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Zhen-Xing Li, Jin-Hong Hu, Rong-Shuang Luo, Tai-Hong Zhang, Yue Ding, Xiang Zhou, Li-Wei Liu, Zhi-Bing Wu, Song Yang
Summary: This study established an efficient screening platform based on natural alkaloids to discover novel compounds targeting TMV helicase. Rutaecarpine from Evodia rutaecarpa (Juss.) Benth showed excellent TMV helicase inhibitory properties (Kd = 1.1 μm, IC50 = 227.24 μm) and demonstrated strong anti-TMV activity. Molecular docking and dynamic simulations revealed that Rutaecarpine could stably bind to the active pockets of the helicase through hydrogen bonding and hydrophobic interactions with low binding energy (ΔG(bind) = -17.8 kcal/mol).
PEST MANAGEMENT SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Xia Yu, Jiawei Li, Hao Zhang, Min-Hui Li, Jun Hu
Summary: Using natural glycyrrhetinic acid (GA) with good self-assembly ability and hydrophilic polyethylene glycol (PEG) with thermoresponsive capacity, we synthesized amphiphilic trans-/cis-TPE-GA-PEG isomers with aggregation-induced emission (AIE) characteristics. The trans isomers formed nanospheres with typical AIE features, while the cis isomers displayed a fluorescence-enhanced property and generated nanovesicles. Both isomers underwent reversible phase transitions in tetrahydrofuran/water solution, with the cis isomers having a lower phase transition temperature compared to the trans-TPE-GA-PEG. The morphologies of the isomers transformed into helical fibers and irregular aggregates, respectively, due to the disruption of interactions between PEG chains and water molecules.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Zhongkai Guo, Xuewei Jiao, Kailun Wei, Jianqiao Wu, Jun Hu
Summary: In this study, a series of itaconic acid-based vitrimers with dual-dynamic networks were prepared by one-pot inverse vulcanization, which resolved the challenges of competitive raw materials and tedious preparation process for application of sustainable polymers. These vitrimers exhibited good solvent resistance and thermal stability, and could be physically recycled, repaired, welded, and chemically degraded at a mild temperature.
Article
Chemistry, Multidisciplinary
Feng Xu, Zao Li, Li-Long Zhang, Shengqi Liu, Hu Li, Yuhe Liao, Song Yang
Summary: Upgrading biomass-derived platforms to functionalized aromatics by a tandem Diels-Alder (DA) cycloaddition-aromatization strategy has attracted attention. Three challenges exist: improving the equilibrium of DA cycloaddition, controlling the regioselectivity of DA adducts, and increasing the stability of the cycloadduct. In this study, an intramolecular cycloaromatization strategy was developed using a defective Zn-BTC-SA catalyst and an acidic ionic liquid to achieve efficient and selective conversion of bio-furfurals to isoindolinones under liquid phase conditions. The protocol showed high yields and scalability.
Article
Chemistry, Multidisciplinary
Long Chen, Yixuan Liu, Heng Zhang, Yuncong Li, Songdang Zhang, Yulin Hu, Hu Li, Song Yang
Summary: Utilization of renewable biomass resources to produce value-added platform molecules, such as anethole, has attracted significant attention. In this study, a green and effective method for the stereoselective conversion of biomass-derived 4'-methoxyphenylacetone into trans-anethole was developed using a bifunctional acid catalyst. The catalyst exhibited a favorable structure with specific surface area, abundant mesopores, acidic sites, hydrophobicity, and stability. The optimized reaction conditions resulted in a high yield and excellent reusability. This catalytic strategy shows promise for the synthesis of anethole and other high-value molecules.
REACTION CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Inorganic & Nuclear
Li-Long Zhang, Yaqiong Su, Dandan Chen, Hongguo Wu, Feng Xu, Hu Li, Song Yang
Summary: NOx is used as an oxidant for direct selective conversion of methane into methanol, but the interconversion of NOx compounds and the easy formation of O-2 have posed challenges in determining its effectiveness. This study proposes a new cooperative multi-functional mechanism strategy using dual oxidants (NO and N2O) to enhance catalytic performance. Compared with normal mechanisms, this strategy shows stronger CH4 adsorption and thermodynamic favorability. It is expected to inspire further research in DSCMM and other catalytic systems.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Physical
Li-Long Zhang, Ji Zheng, Jinxing Gu, Zhuochun Huang, Linguo Lu, Hu Li, Zhongfang Chen, Song Yang
Summary: This study investigated 11 phosphotungstic acid-supported single-atom catalysts (SACs) and found that Os-1/PTA SACs exhibited superior catalytic activity for the purification of methane and hydrogen, with the ease of oxidation following the CO > H-2 > CH4 order. It selectively removed CO in water and MeOH without consuming H-2, due to strong Os-PTA interactions and charge transfer mechanism.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Review
Polymer Science
Wenfeng Zhao, Qinmei Ge, Hu Li, Nan Jiang, Shangwei Chen, Song Yang, Hang Cong
Summary: Using organic polymers as catalysts for CO2 photoreduction is a highly promising approach to addressing energy and environmental issues, due to their outstanding CO2 adsorption capacity, photochemical performance, and tunable structure.
Article
Chemistry, Organic
Faiza Diaba, Gisela Trenchs
Summary: The first violet light-mediated synthesis of gamma- and delta-lactams from N-alkenyl trichloroacetamides is reported in this paper. The reactions are conducted in tetrahydrofuran or 2-methyltetrahydrofuran as the sole solvent without catalysts or additives, under non-anhydrous conditions in an air atmosphere where the solvent serves as the radical initiator.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Feroze Hussain, Sajjad Ahmed, Ashiq Hussain Padder, Qazi Naveed Ahmed
Summary: This study reports a novel and efficient one-pot synthesis method for mixed phosphorotrithioates, which does not require supplementary additives and shows broad applicability.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Hyunjin Oh, Ikyon Kim
Summary: A new 1,2,4-triazole-pyrrolo[1,2-a]pyrazine hybrid system, 6-acylpyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, was synthesized using a catalyst-free method. This method involved sequential exposure of pyrrole-2-carbonitrile-derived substrates to DMF-DMA and acyl hydrazide, resulting in the formation of acylated pyrazine and 1,2,4-triazole rings, enabling the installation of various substituents at specific positions on the core skeleton.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Ming Yan, Si-fan Wang, Yong-po Zhang, Jin-zhong Zhao, Zhuo Tang, Guang-xun Li
Summary: Here we developed an efficient photocatalytic approach for the convenient preparation of sulfinamides. The reaction allows for the gram-scale preparation of sulfinamides and the one-pot synthesis of various sulfonyl amides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Farzaneh Bandehali-Naeini, Zahra Tanbakouchian, Noushin Farajinia-Lehi, Nicolas Mayer, Morteza Shiri, Martin Breugst
Summary: Two tandem catalytic systems were developed for the synthesis of novel 3,4-disubstituted maleimides using the same Ugi adducts. Different maleimide structures can be synthesized using either Pd or Cu catalysis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Tanya Raghava, Anjan Chattopadhyay, Subhadeep Banerjee, Nivedita Sarkar
Summary: Amine substitution of two ortho fluorine atoms of tetrafluoroterephthalonitrile through SNAr chemistry is easily achievable. But further fluorine substitution is only possible under forcing conditions, yielding valuable fluorophores for bioimaging.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Review
Chemistry, Organic
Anju Chadha, Santosh Kumar Padhi, Selvaraj Stella, Sowmyalakshmi Venkataraman, Thangavelu Saravanan
Summary: Alcohol dehydrogenases are enzymes that use cofactors for oxidation or reduction reactions of alcohols or carbonyl compounds. They are utilized in green chemistry and have applications in the production of pharmaceuticals. Recombinant enzymes have solved the challenge of producing purified enzymes in large quantities. Engineered alcohol dehydrogenases have been used in asymmetric synthesis in industry. Various methods have been established for regenerating expensive cofactors to make the enzymatic process more efficient and economically viable.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
