Enantioselective palladium catalyzed conjugate additions of ortho-substituted arylboronic acids to β,β-disubstituted cyclic enones: total synthesis of herbertenediol, enokipodin A and enokipodin B

A Multicomponent Ni-, Zr-, and Cu-Catalyzed Strategy for Enantioselective Synthesis of Alkenyl-Substituted Quaternary Carbons

(2014) Kevin P. McGrath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective 1,4-additions of ClMeAl(CHCHR) (R = alkyl, alkenyl, Ph) to cyclohexenones

(2014) D. Willcox et al.   CHEMICAL COMMUNICATIONS

Enantioselective construction of remote quaternary stereocentres

(2014) Tian-Sheng Mei et al.   NATURE

Total Synthesis of (–)-HM-3 and (–)-HM-4 Utilizing a Palladium-Catalyzed Addition of an Arylboronic Acid to an Allenic Alcohol Followed by Eschenmoser–Claisen Rearrangement

(2014) Masahiro Yoshida et al.   SYNLETT

Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Conjugate Additions of Aryl- and Alkylaluminum Reagents to Acyclic Trisubstituted Enones

(2013) Jennifer A. Dabrowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining NHC-Cu and Brønsted Base Catalysis: Enantioselective Allylic Substitution/Conjugate Additions with Alkynylaluminum Reagents and Stereospecific Isomerization of the Products to Trisubstituted Allenes

(2013) Jennifer A. Dabrowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selection of boron reagents for Suzuki–Miyaura coupling

(2013) Alastair J. J. Lennox et al.   CHEMICAL SOCIETY REVIEWS

Reagent Control of [1,2]-Wagner-Meerwein Shift Chemoselectivity Following the Nazarov Cyclization: Application to the Total Synthesis of Enokipodin B

(2013) David Lebœuf et al.   CHEMISTRY-A EUROPEAN JOURNAL

Formation of Quaternary Stereogenic Centers by Copper-Catalyzed Asymmetric Conjugate Addition Reactions of Alkenylaluminums to Trisubstituted Enones

(2013) Daniel Müller et al.   CHEMISTRY-A EUROPEAN JOURNAL

Efficient Formation of Benzylic Quaternary Centers via Palladium Catalysis

(2013) Aditya L. Gottumukkala et al.   ChemSusChem

Protodeboronation of ortho- and para-Phenol Boronic Acids and Application to ortho and meta Functionalization of Phenols Using Boronic Acids as Blocking and Directing Groups

(2013) Chun-Young Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β-Substituted Cyclic Enones: Insights from Computation and Experiment

(2013) Jeffrey C. Holder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Trapping of Sterically Encumbered Aluminum Enolates

(2013) Christian Bleschke et al.   ORGANIC LETTERS

Creation of Highly Congested Quaternary Centers via Cu-catalyzed Conjugate Addition of Alkenyl Alanates to β-Substituted Cyclic Enones

(2013) Daniel Müller et al.   ORGANIC LETTERS

Diastereodivergent Synthesis of Trisubstituted Alkenes through Protodeboronation of Allylic Boronic Esters: Application to the Synthesis of the Californian Red Scale Beetle Pheromone

(2012) Matthew J. Hesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium and copper-catalyzed asymmetric conjugate addition of alkenyl nucleophiles

(2012) Daniel Müller et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Asymmetric Quaternary Stereocenter Formation

(2012) Aditya L. Gottumukkala et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective synthesis of all-carbon quaternary stereogenic centers in acyclic systems

(2011) Jaya Prakash Das et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters

(2011) Kotaro Kikushima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Experimental Conditions for Tandem hydroalumination/Cu-Catalyzed Asymmetric Conjugate Additions to β-Substituted Cyclic Enones

(2011) Daniel Müller et al.   ORGANIC LETTERS

Highly Enantioselective and Regioselective Copper-Catalyzed 1,4 Addition of Grignard Reagents to Cyclic Enynones

(2011) Matthieu Tissot et al.   ORGANIC LETTERS

Direct aerobic α,β-dehydrogenation of aldehydes and ketones with a Pd(TFA)2/4,5-diazafluorenone catalyst

(2011) Tianning Diao et al.   Chemical Science

Rhodium-Catalyzed Asymmetric 1,4-Addition of Aryl Alanes to Trisubstituted Enones: Binap as an Effective Ligand in the Formation of Quaternary Stereocenters

(2010) Christine Hawner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Tetrafluorobenzobarrelenes as Effective Ligands for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboroxines to β,β-Disubstituted α,β-Unsaturated Ketones

(2010) Ryo Shintani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters

(2010) Christine Hawner et al.   CHEMICAL COMMUNICATIONS

Synthesis of (-)-herbertenediol and (aR, aS)-mastigophorenes A via asymmetric intramolecular heck coupling reaction

(2010) Ai-Min Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

The Slow-Release Strategy in Suzuki-Miyaura Coupling

(2010) Alastair J. J. Lennox et al.   ISRAEL JOURNAL OF CHEMISTRY

Protodeboronation of Tertiary Boronic Esters: Asymmetric Synthesis of Tertiary Alkyl Stereogenic Centers

(2010) Stefan Nave et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formation of Vinyl-, Vinylhalide- or Acyl-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Enantioselective Conjugate Additions of Si-Containing Vinylaluminums to β-Substituted Cyclic Enones

(2010) Tricia L. May et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic Pd(II)/Bipyridine-Catalyzed Conjugate Addition of Arylboronic Acids to β,β-Disubstituted Enones: Construction of Quaternary Carbon Centers

(2010) Shaohui Lin et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric 1,4-Addition of Sodium Tetraarylborates to β,β-Disubstituted α,β-Unsaturated Esters

(2010) Ryo Shintani et al.   ORGANIC LETTERS

Palladium (II) catalyzed 5-endo epoxynitrile cyclizations: total syntheses of enokipodins A and B

(2010) Jesús Armando Luján-Montelongo et al.   TETRAHEDRON LETTERS

Olefin-Oxazolines (OlefOx): Highly Modular, Easily Tunable Ligands for Asymmetric Catalysis

(2009) Björn T. Hahn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of All-Carbon Benzylic Quaternary Stereocenters via Conjugate Addition to Alkylidene and Indenylidene Meldrum’s Acids

(2009) Ashraf Wilsily et al.   JOURNAL OF ORGANIC CHEMISTRY

Sodium Tetraarylborates as Effective Nucleophiles in Rhodium/Diene-Catalyzed 1,4-Addition to β,β-Disubstituted α,β-Unsaturated Ketones: Catalytic Asymmetric Construction of Quaternary Carbon Stereocenters

(2009) Ryo Shintani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Syntheses of Enokipodins A and B Utilizing Palladium-Catalyzed Addition of An Arylboronic Acid to An Allene

(2009) Masahiro Yoshida et al.   ORGANIC LETTERS

Copper-Catalyzed Asymmetric Conjugate Addition of Aryl Aluminum Reagents to Trisubstituted Enones: Construction of Aryl-Substituted Quaternary Centers

(2008) Christine Hawner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five-, Six-, and Seven-Membered-Ring β-Substituted Cyclic Enones

(2008) Tricia L. May et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Carboxylic Acid Derivatives Having an All-Carbon α-Quaternary Center through Cu-Catalyzed 1,4-Addition of Dialkylzinc Reagents to 2-Aryl Acetate Derivatives

(2008) Ashraf Wilsily et al.   ORGANIC LETTERS