Synthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (σ2) selective ligands

The σ2 Receptor: A Novel Protein for the Imaging and Treatment of Cancer

(2013) Robert H. Mach et al.   JOURNAL OF MEDICINAL CHEMISTRY

Electron-donating para-methoxy converts a benzamide-isoquinoline derivative into a highly Sigma-2 receptor selective ligand

(2011) Abdol R. Hajipour et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of structural modification in the amine portion of substituted aminobutyl-benzamides as ligands for binding σ1 and σ2 receptors

(2011) Kuo-Hsien Fan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers

(2011) Carmen Abate et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

(2011) Jinbin Xu et al.   Nature Communications

Radiosynthesis and biological evaluation of a promising σ2-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer

(2010) Zhude Tu et al.   APPLIED RADIATION AND ISOTOPES

Sigma Receptors in Oncology: Therapeutic and Diagnostic Applications of Sigma Ligands

(2010) Aren van Waarde et al.   CURRENT PHARMACEUTICAL DESIGN

Progesterone Receptor Membrane Component 1 (Pgrmc1): A Heme-1 Domain Protein That Promotes Tumorigenesis and Is Inhibited by a Small Molecule

(2010) I. S. Ahmed et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands

(2009) E. Cobos et al.   Current Neuropharmacology

N-(4-(4-(2,3-Dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with Functionalized Linking Chains as High Affinity and Enantioselective D3 Receptor Antagonists∥⊥

(2009) Amy Hauck Newman et al.   JOURNAL OF MEDICINAL CHEMISTRY

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma

(2008) Nicola Antonio Colabufo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cytotoxicity of  -Receptor Ligands Is Associated with Major Changes of Cellular Metabolism and Complete Occupancy of the  -2 Subpopulation

(2008) A. A. Rybczynska et al.   JOURNAL OF NUCLEAR MEDICINE