Electron densities of bexarotene and disila-bexarotene from invariom application: a comparative study

Electron density study of the anti-Alzheimer’s disease drug donepezil from conventional x-ray data and invariom database application

(2012) Peter Luger et al.   Future Medicinal Chemistry

Organosilicon Molecules with Medicinal Applications

(2012) Annaliese K. Franz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation

(2012) Josef B. G. Gluyas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ApoE-Directed Therapeutics Rapidly Clear  -Amyloid and Reverse Deficits in AD Mouse Models

(2012) P. E. Cramer et al.   SCIENCE

Electron Density of Two Bioactive Oligocyclic Indole and Oxindole Derivatives Obtained from Low-Order X-Ray Data and Invariom Application

(2011) Manuela Weber et al.   Chemistry-An Asian Journal

High-Affinity, Selective σ Ligands of the 1,2,3,4-Tetrahydro-1,4′-silaspiro[naphthalene-1,4′-piperidine] Type: Syntheses, Structures, and Pharmacological Properties

(2011) Reinhold Tacke et al.   ChemMedChem

Novel Silicon-Containing Analogues of the Retinoid Agonist Bexarotene: Syntheses and Biological Effects on Human Pluripotent Stem Cells

(2011) Jennifer B. Bauer et al.   ChemMedChem

Silicon Analogues of the Nonpeptidic GnRH Antagonist AG-045572: Syntheses, Crystal Structure Analyses, and Pharmacological Characterization

(2011) Matthew J. Barnes et al.   ChemMedChem

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Validation of experimental charge densities: refinement of the macrolide antibiotic roxithromycin

(2010) J. J. Holstein et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

A simple procedure for the derivation of electron density based surfaces of drug-receptor complexes from a combination of X-ray data and theoretical calculations

(2010) Stefan Mebs et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sila-Trifluperidol, a Silicon Analogue of the Dopamine (D2) Receptor Antagonist Trifluperidol: Synthesis and Pharmacological Characterization

(2010) Reinhold Tacke et al.   ORGANOMETALLICS

Transferability and reproducibility in electron-density studies – bond-topological and atomic properties of tripeptides of the typeL-alanyl-X-L-alanine

(2009) Simon Grabowsky et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

How to easily replace the independent atom model – the example of bergenin, a potential anti-HIV agent of traditional Asian medicine

(2009) Birger Dittrich et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

Synthesis and Pharmacological Characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, Silicon Analogues of the RARα-Selective Retinoid Agonists AM80 (Tamibarotene) and AM580

(2009) Reinhold Tacke et al.   ChemMedChem

Silicon Analogues of the RXR-Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology

(2009) W. Peter Lippert et al.   ChemMedChem

In Vitro Metabolism of Haloperidol and Sila-Haloperidol: New Metabolic Pathways Resulting from Carbon/Silicon Exchange

(2009) T. Johansson et al.   DRUG METABOLISM AND DISPOSITION

How to Make the Ionic Si−O Bond More Covalent and the Si−O−Si Linkage a Better Acceptor for Hydrogen Bonding†

(2009) Simon Grabowsky et al.   INORGANIC CHEMISTRY

Environmental Effects on Charge Densities of Biologically Active Molecules: Do Molecule Crystal Environments Indeed Approximate Protein Surroundings?

(2009) Milena Mladenovic et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Improvement of anisotropic displacement parameters from invariom-model refinements for threeL-hydroxylysine structures

(2008) B. Dittrich et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE