Synthesis, biological evaluation, and structure–activity relationships of tri- and tetrasubstituted olefins related to isocombretastatin A-4 as new tubulin inhibitors

Tubulin-based Structure-affinity Relationships for Antimitotic Vinca Alkaloids

(2012) Claire Coderch et al.   Anti-Cancer Agents in Medicinal Chemistry

Collateral sensitivity as a strategy against cancer multidrug resistance

(2012) Kristen M. Pluchino et al.   DRUG RESISTANCE UPDATES

Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity

(2012) Evelia Rasolofonjatovo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A One-Pot Three-Step Synthesis of Z-Trisubstituted Olefins from Arylalkynes and Their Cyclization into 4-Aryl-2H-chromenes

(2012) Evelia Rasolofonjatovo et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 1,1-Diarylethylenes via Efficient Iron/Copper Co-Catalyzed Coupling of 1-Arylvinyl Halides with Grignard Reagents

(2012) Abdallah Hamze et al.   ORGANIC LETTERS

Tosylhydrazones: New Uses for Classic Reagents in Palladium-Catalyzed Cross-Coupling and Metal-Free Reactions

(2011) José Barluenga et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

N-Tosylhydrazones: versatile reagents for metal-catalyzed and metal-free cross-coupling reactions

(2011) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Discovery of Isoerianin Analogues as Promising Anticancer Agents

(2011) Samir Messaoudi et al.   ChemMedChem

B-Ring-Modified isoCombretastatin A-4 Analogues Endowed with Interesting Anticancer Activities

(2011) Abdallah Hamze et al.   ChemMedChem

Biological Potential and Structure-Activity Relationships of Most Recently Developed Vascular Disrupting Agents: An Overview of New Derivatives of Natural Combretastatin A-4

(2011) M. Marrelli et al.   CURRENT MEDICINAL CHEMISTRY

Copper-catalyzed reductive coupling of tosylhydrazones with amines: A convenient route to α-branched amines

(2011) Abdallah Hamze et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Phase Ib trial of CA4P (combretastatin A-4 phosphate), carboplatin and paclitaxel in patients with advanced cancer

(2010) G J Rustin et al.   BRITISH JOURNAL OF CANCER

Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4

(2010) Evelia Rasolofonjatovo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pd-Catalyzed Reaction of Sterically Hindered Hydrazones with Aryl Halides: Synthesis of Tetra-Substituted Olefins Related toiso-Combretastatin A4

(2010) Etienne Brachet et al.   ORGANIC LETTERS

Palladium-catalyzed coupling of N-tosylhydrazones with ortho substituted aryl halides: synthesis of 4-arylchromenes and related heterocycles

(2010) Evelia Rasolofonjatovo et al.   TETRAHEDRON LETTERS

Synthesis, Biological Evaluation of 1,1-Diarylethylenes as a Novel Class of Antimitotic Agents

(2009) Abdallah Hamze et al.   ChemMedChem

AVE8062: a new combretastatin derivative vascular disrupting agent

(2009) Angelo Delmonte et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Isocombretastatins A versus Combretastatins A: The ForgottenisoCA-4 Isomer as a Highly Promising Cytotoxic and Antitubulin Agent

(2009) Samir Messaoudi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Expeditious synthesis of 1,1-diarylethylenes related to isocombretastatin A-4 (isoCA-4) via palladium-catalyzed arylation of N-tosylhydrazones with aryl triflates

(2009) Bret Tréguier et al.   TETRAHEDRON LETTERS

Synthesis and antitumor activity of benzils related to combretastatin A-4

(2008) Céline Mousset et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Palladium-Catalyzed Markovnikov Terminal Arylalkynes Hydrostannation: Application to the Synthesis of 1,1-Diarylethylenes

(2008) Abdallah Hamze et al.   JOURNAL OF ORGANIC CHEMISTRY

Halogenation of ketones with N-halosuccinimides under solvent-free reaction conditions

(2008) Igor Pravst et al.   TETRAHEDRON