Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold

COX-2 as a target for cancer chemotherapy

(2014) Nilanjan Ghosh et al.   Pharmacological Reports

Fully automated synthesis of 4-[18F]fluorobenzylamine based on borohydride/NiCl2 reduction

(2013) Jenilee Way et al.   NUCLEAR MEDICINE AND BIOLOGY

Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

(2012) Torsten Kniess et al.   BIOORGANIC & MEDICINAL CHEMISTRY

COX-2 Inhibitors and Cardiovascular Risk

(2012) C. P. Cannon et al.   SCIENCE

Novel Strategies for Fluorine-18 Radiochemistry

(2011) Ryan Littich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [11C]celecoxib and its major metabolite [11C]SC-62807 and in vivo PET evaluation

(2011) Misato Takashima-Hirano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer

(2011) M. J. Uddin et al.   Cancer Prevention Research

A novel three-step synthesis of Celecoxib via palladium-catalyzed direct arylation

(2011) Steven M. Gaulier et al.   TETRAHEDRON LETTERS

Synthesis and application of 4-[18F]fluorobenzylamine: A versatile building block for the preparation of PET radiotracers

(2010) Ingrid Koslowsky et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of carbon-11 labeled celecoxib derivatives as new candidate PET radioligands for imaging of inflammation

(2009) Mingzhang Gao et al.   APPLIED RADIATION AND ISOTOPES

Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors

(2009) Martin E. Swarbrick et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

The role of COX-2 in intestinal inflammation and colorectal cancer

(2009) D Wang et al.   ONCOGENE

Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor

(2008) Frank Wuest et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Radiolabeling of a high potency cannabinoid subtype-1 receptor ligand,N-(4-fluoro-benzyl)-4-(3-(piperidin-1-yl)-indole-1-sulfonyl)benzamide (PipISB), with carbon-11 or fluorine-18

(2008) Sean R. Donohue et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Evaluation of [11C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation

(2007) Erik F.J. de Vries et al.   NUCLEAR MEDICINE AND BIOLOGY