Thiol–yne radical reaction mediated site-specific protein labeling via genetic incorporation of an alkynyl-l-lysine analogue

Ligation of Expressed Protein α-Hydrazides via Genetic Incorporation of an α-Hydroxy Acid

(2012) Yi-Ming Li et al.   ACS Chemical Biology

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

(2012) Emine Kaya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preventing Thiol-Yne Addition Improves the Specificity of Strain-Promoted Azide–Alkyne Cycloaddition

(2012) Remon van Geel et al.   BIOCONJUGATE CHEMISTRY

Targeting Deubiquitinases Enabled by Chemical Synthesis of Proteins

(2012) Shimrit Ohayon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

Ionization state of the catalytic dyad Asp25/25′ in the HIV-1 protease: NMR studies of site-specifically 13C labelled HIV-1 protease prepared by total chemical synthesis

(2012) Vladimir Yu. Torbeev et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications

(2012) Alessandro Massi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Genetically encoded alkenyl–pyrrolysine analogues for thiol–ene reaction mediated site-specific protein labeling

(2012) Yiming Li et al.   Chemical Science

Bioorthogonal Chemistry for Site-Specific Labeling and Surface Immobilization of Proteins

(2011) Yong-Xiang Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficientin VivoIncorporation of Structurally Divergent Non-native Amino Acids

(2011) Jeffrey K. Takimoto et al.   ACS Chemical Biology

Convergent Chemical Synthesis of [Lysine24, 38, 83] Human Erythropoietin

(2011) Suhuai Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Chemical Synthesis by Ligation of Peptide Hydrazides

(2011) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Revealing the nature of thio-click reactions on the solid phase

(2011) M. Talha Gokmen et al.   CHEMICAL COMMUNICATIONS

A readily synthesized cyclic pyrrolysine analogue for site-specific protein “click” labeling

(2011) Ziyang Hao et al.   CHEMICAL COMMUNICATIONS

Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin

(2011) Cang Wang et al.   CHEMICAL COMMUNICATIONS

Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

(2011) Yugang Huang et al.   CHEMICAL COMMUNICATIONS

Multi-molecule reaction of serum albumin can occur through thiol-yne coupling

(2011) Mauro Lo Conte et al.   CHEMICAL COMMUNICATIONS

Reprogramming the genetic code

(2011) Jason W Chin   EMBO JOURNAL

Fmoc Synthesis of Peptide Thioesters without Post-Chain-Assembly Manipulation

(2011) Ji-Shen Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Genetic Code of an Animal

(2011) Sebastian Greiss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiol-Yne Chemistry: A Powerful Tool for Creating Highly Functional Materials

(2010) Richard Hoogenboom   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Hyperbranched alternating block copolymers using thiol–yne chemistry: materials with tuneable properties

(2010) Dominik Konkolewicz et al.   CHEMICAL COMMUNICATIONS

Photoinduced Addition of Glycosyl Thiols to Alkynyl Peptides: Use of Free-Radical Thiol−Yne Coupling for Post-Translational Double-Glycosylation of Peptides

(2010) Mauro Lo Conte et al.   JOURNAL OF ORGANIC CHEMISTRY

Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair

(2010) Susan M. Hancock et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiyl Glycosylation of Olefinic Proteins: S-Linked Glycoconjugate Synthesis

(2009) Nicola Floyd et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells

(2009) Peng R. Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Poly(ethylene glycol) hydrogels formed by thiol-ene photopolymerization for enzyme-responsive protein delivery

(2009) Alex A. Aimetti et al.   BIOMATERIALS

Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications

(2009) Ying Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Expanding the Genetic Code for Biological Studies

(2009) Qian Wang et al.   CHEMISTRY & BIOLOGY

A Photoinducible 1,3-Dipolar Cycloaddition Reaction for Rapid, Selective Modification of Tetrazole-Containing Proteins

(2008) Wenjiao Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry

(2008) Alessandro Dondoni   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases

(2008) Takahito Mukai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thiol−Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks

(2008) Benjamin D. Fairbanks et al.   MACROMOLECULES

Genetically encoding Nε-acetyllysine in recombinant proteins

(2008) Heinz Neumann et al.   Nature Chemical Biology