Discovery of indolyl acrylamide derivatives as human diacylglycerol acyltransferase-2 selective inhibitors

Thiadiazoles as new inhibitors of diacylglycerol acyltransferase type 1

(2012) Patrick Mougenot et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2

(2012) Jenson Qi et al.   JOURNAL OF LIPID RESEARCH

Design and synthesis of potent carboxylic acid DGAT1 inhibitors with high cell permeability

(2011) Ustav Bali et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis

(2011) Andreia C Turchetto-Zolet et al.   BMC EVOLUTIONARY BIOLOGY

Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases

(2011) Jingsong Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

(2011) Yimin Qian et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1

(2011) Robert L. Dow et al.   ACS Medicinal Chemistry Letters

Novel acyl coenzyme A (CoA): Diacylglycerol acyltransferase-1 inhibitors: Synthesis and biological activities of diacylethylenediamine derivatives

(2010) Yoshihisa Nakada et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel Acyl Coenzyme A: Diacylglycerol Acyltransferase 1 Inhibitors—Synthesis and Biological Activities of N-(Substituted heteroaryl)-4-(substituted phenyl)-4-oxobutanamides

(2010) Yoshihisa Nakada et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease

(2010) Zhigang Wang et al.   JOURNAL OF LIPID RESEARCH

Inhibitors of diacylglycerol acyltransferase: a review of 2008 patents

(2009) Andrew J King et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery of a Potent, Selective, and Orally Efficacious Pyrimidinooxazinyl Bicyclooctaneacetic Acid Diacylglycerol Acyltransferase-1 Inhibitor

(2009) Alan M. Birch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor

(2008) Gang Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY