Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 40, Pages 8048-8050Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob25801c
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Funding
- Shanghai Municipal Committee of Science and Technology [11JC1402600]
- National Basic Research Program of China (973) [2010CB833302]
- Fundamental Research Funds for the Central Universities
- National Natural Science Foundation of China [21072206, 20872162, 20672127, 20732008, 21121062, 20702013]
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DIOP catalyzed highly enantioselective [3 + 2] annulation of N-protected isatins with but-3-yn-2-one has been disclosed, allowing the synthesis of enantioenriched spiro[furan-2,3'-indoline]-2',4(5H)-dione in moderate yields along with good to high enantioselectivities under mild conditions.
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