Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 10, Issue 47, Pages 9429-9439Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob26668g
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- Cultivation Foundation for the New Faculties from Tianjin University [60302010]
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Relatively less expensive Pd-catalysed oxidative coupling reactions for the preparation of N-alkyl and N-aryl substituted isoquinolones and their derivatives have been developed. A broad reaction scope has been demonstrated. In addition, studies of the reaction additives and mechanistic insights, as well as KIE studies for a better understanding of the reaction pathway, have been discussed.
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