Article
Chemistry, Medicinal
Irfan Muhammad, Ghulam Murtaza, Yi Zhao, Aysha Sarfraz Rizvi, Shangnan Fu, Xin Su, Feng Qu
Summary: A new analytical method using free aptamer as a detection probe for the sensitive and selective detection of cadmium ions in environmental samples was developed based on capillary zone electrophoresis. This method exhibited high sensitivity and specificity, with detection within 4 minutes in the range from 5 to 250 nM and a limit of detection of 5 nM. The method can be expanded for the design of aptasensors for other targets.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2023)
Article
Chemistry, Physical
Arepati Azhati, Lu Han, Zhibei Qu, Zhouhong Ren, Xi Liu, Liwei Chen, Shunai Che
Summary: The self-assembly of DNA plays a significant role in understanding structural formation in living organisms and materials chemistry. This study investigates the impact of metal ions on the chiral self-assembly of DNA and discovers that certain metal ions induce the formation of chiral DNA complexes. The study also explores the interaction between metal ions and DNA, providing insights into the mechanism of chiral stacking.
Article
Chemistry, Multidisciplinary
Arlin Rodriguez, Dhanush Gandavadi, Johnsi Mathivanan, Tingjie Song, Bharath Raj Madhanagopal, Hannah Talbot, Jia Sheng, Xing Wang, Arun Richard Chandrasekaran
Summary: The programmable nature of DNA allows the construction of custom-designed static and dynamic nanostructures. However, the high concentrations of magnesium ions required for assembly restrict their applications. In this study, we investigate the assembly of DNA nanostructures in various ions and successfully assemble a majority of these structures in Ca2+, Ba2+, Na+, K+ and Li+. We also find that structures assembled in monovalent ions exhibit significantly higher nuclease resistance compared to those assembled in divalent ions.
Article
Chemistry, Multidisciplinary
Yujie Song, Xiao Xie, Yang Liu, Zhen Zhu, Litao Sun
Summary: Metal ions, especially Cu2+, play vital roles in various biochemical reactions in the human body and are essential for maintaining good health. This study investigates the interaction between Cu2+ and DNA using transmission electron microscopy (TEM) and in situ liquid-cell TEM. Results demonstrate that the binding of Cu2+ to DNA results in the bending of the DNA strand and provides a site for the nucleation and growth of copper crystals. The arrangement of the copper crystals along the curved DNA strand correlates with the guanine arrangement on the DNA sequence. This research provides a direct observation of the DNA-Cu2+ complex at the nanometer scale and contributes to further understanding the interaction mechanism, benefiting biomedical research.
Article
Chemistry, Analytical
Maofei Wang, Masaki Tsukamoto, Vladimir G. Sergeyev, Anatoly Zinchenko
Summary: Fluorescent nanoparticles (biodots) were synthesized from DNA, RNA, and RNA nucleotides to study their metal ion sensing characteristics. The biodots show high sensitivity to mercury ions and can be used for analytic detection of mercury ion concentration. A paper strip test was also developed for visual detection of mercury ions in solutions.
Article
Materials Science, Multidisciplinary
Ahmed Shawky, Nadiyah Alahmadi, R. M. Mohamed, Z. Zaki
Summary: This study demonstrates the construction of nanostructured Bi2S3/TiO2 as a visible-light active photocatalyst for the rapid reduction of Cr(VI) to Cr(III). The developed photocatalyst achieved a fast photocatalytic reduction of Cr(VI) at 284.2 μmol min(-1) within just 30 min at a dose of 2.0 g/L.
Article
Chemistry, Multidisciplinary
Kanishka Sikligar, Steven P. P. Kelley, Durgesh V. V. Wagle, Piyuni Ishtaweera, Gary A. A. Baker, Jerry L. L. Atwood
Summary: A new class of voluminous crystalline compounds formed by divalent calcium ion binding to pyrogallol[4]arene-based hierarchical geometries has been discovered. The structures of these nanocapsules, determined through single-crystal X-ray analysis, show a highly conserved cubic shape with C-ethylpyrogallol[4]arene units along the cube edges, bridged by metallic polyatomic cations. The nanocapsules have an isolated volume of approximately 3500 &ANGS;(3) and 2500 &ANGS;(3). This discovery opens up possibilities for exploring diverse supramolecular assemblies, networks, and capsules using calcium, with potential applications in drug delivery, nutrition, preservation, and antioxidants.
Article
Chemistry, Analytical
Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao, Shan Huang
Summary: A label-free and ultrasensitive electrochemical biosensor for oral cancer overexpressed 1 (ORAOV1) gene was constructed using exonuclease III-assisted target recycling and dual enzyme-assisted signal amplification strategies. The biosensor can accurately detect ORAOV1 gene in human saliva samples.
Review
Chemistry, Physical
Jiaojiao Zhou, Heyou Han, Juewen Liu
Summary: Metal ions can coordinate with nucleotides (or DNA) to produce a variety of nanoparticles, fibers, and hydrogels. These coordination materials possess luminescent, catalytic, and molecular recognition properties, and have applications in biosensing, enzyme encapsulation, catalysis, templated shell growth, and cancer therapy.
Article
Chemistry, Multidisciplinary
Mahesh Sundararajan
Summary: Several uranyl ions with Schiff-base ligands and redox-innocent metal ions were synthesized, and their reduction potentials were estimated. The change in Lewis acidity of the metal ions contributes to quantified values of approximately 60 mV per pKa unit. The presence of triflate molecules near the metal ions, which also increases with the Lewis acidity of the metal ions, has poorly understood and unquantified contributions to the redox potentials. In this study, the individual contributions of Lewis acid metal ions and triflate anions were quantified and analyzed using electronic structure calculations. It was found that triflate anions, especially in the case of divalent and trivalent anions, can contribute more than 50% to the predicted redox potentials, challenging the previous assumption of their innocence and highlighting their vital role in the overall reduction processes.
Article
Biochemistry & Molecular Biology
Jinghua Hao, Dong Cao, Qiang Zhao, Dapeng Zhang, Hailin Wang
Summary: It has been discovered that Ag+ can interact with polyT oligonucleotides to form an Ag+-bridged T-Ag+-T structure once the concentration of Ag+ in solution exceeds a certain threshold value. The intramolecular folding of the polyT oligonucleotide has a higher thermal stability than the duplex and can be reversibly modulated by cysteine.
Article
Materials Science, Multidisciplinary
Roman Nickisch, Wiebe M. de Vos, Michael A. R. Meier, Muhammad Irshad Baig
Summary: In this study, polymeric membranes with metal-complexing ligands were prepared using polythiosemicarbazone (pTSC) as the material. The membranes exhibited asymmetric structures and porous properties controlled by the polymer concentration. The pTSC membranes showed efficient removal of silver and copper ions in both batch and dynamic adsorption experiments, and they could be successfully reused after partial desorption of silver ions.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Energy & Fuels
Yan Lin, Haitao Wang, Shiwen Fang, Hongming Jiang, Zhen Huang, Guoqiang Wei, Xiaobo Wang, Zengli Zhao, Hongyu Huang
Summary: The study investigates the effects of particle size and temperature on the chemical looping combustion (CLC) of lignite, using iron ore as the oxygen carrier with added alkaline-earth metals and transition metals. The modification of the oxygen carrier with Cu, K, Na, Ca, and Mn enhances its capacity to transform lignite and improve CO2 selectivity, with potential applications in the design of oxygen carriers for the CLC process.
Article
Energy & Fuels
Yan Lin, Haitao Wang, Shiwen Fang, Hongming Jiang, Zhen Huang, Guoqiang Wei, Xiaobo Wang, Zengli Zhao, Hongyu Huang
Summary: This paper investigates the effects of particle size and temperature on the chemical looping combustion of lignite using iron ore as the oxygen carrier. The modification of the oxygen carrier with Cu, K, Na, Ca and Mn effectively enhances the capacity for lignite transformation.
Article
Multidisciplinary Sciences
Shuke Xiao, Lisa S. Baik, Xueying Shang, John R. Carlson
Summary: The study reveals that fruit flies exhibit avoidance behavior towards elevated concentrations of heavy metal ions, which they rarely or never encountered before the Anthropocene. Different subsets of taste receptors contribute to the avoidance of different metal ions, with certain bitter-sensing neurons being activated and sugar-sensing neurons being inhibited by the metal ions. These findings suggest essential mechanisms for insects to cope with environmental changes in the Anthropocene.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Chemistry, Organic
Faiza Diaba, Gisela Trenchs
Summary: The first violet light-mediated synthesis of gamma- and delta-lactams from N-alkenyl trichloroacetamides is reported in this paper. The reactions are conducted in tetrahydrofuran or 2-methyltetrahydrofuran as the sole solvent without catalysts or additives, under non-anhydrous conditions in an air atmosphere where the solvent serves as the radical initiator.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Feroze Hussain, Sajjad Ahmed, Ashiq Hussain Padder, Qazi Naveed Ahmed
Summary: This study reports a novel and efficient one-pot synthesis method for mixed phosphorotrithioates, which does not require supplementary additives and shows broad applicability.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Hyunjin Oh, Ikyon Kim
Summary: A new 1,2,4-triazole-pyrrolo[1,2-a]pyrazine hybrid system, 6-acylpyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, was synthesized using a catalyst-free method. This method involved sequential exposure of pyrrole-2-carbonitrile-derived substrates to DMF-DMA and acyl hydrazide, resulting in the formation of acylated pyrazine and 1,2,4-triazole rings, enabling the installation of various substituents at specific positions on the core skeleton.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Ming Yan, Si-fan Wang, Yong-po Zhang, Jin-zhong Zhao, Zhuo Tang, Guang-xun Li
Summary: Here we developed an efficient photocatalytic approach for the convenient preparation of sulfinamides. The reaction allows for the gram-scale preparation of sulfinamides and the one-pot synthesis of various sulfonyl amides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Farzaneh Bandehali-Naeini, Zahra Tanbakouchian, Noushin Farajinia-Lehi, Nicolas Mayer, Morteza Shiri, Martin Breugst
Summary: Two tandem catalytic systems were developed for the synthesis of novel 3,4-disubstituted maleimides using the same Ugi adducts. Different maleimide structures can be synthesized using either Pd or Cu catalysis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Tanya Raghava, Anjan Chattopadhyay, Subhadeep Banerjee, Nivedita Sarkar
Summary: Amine substitution of two ortho fluorine atoms of tetrafluoroterephthalonitrile through SNAr chemistry is easily achievable. But further fluorine substitution is only possible under forcing conditions, yielding valuable fluorophores for bioimaging.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Review
Chemistry, Organic
Anju Chadha, Santosh Kumar Padhi, Selvaraj Stella, Sowmyalakshmi Venkataraman, Thangavelu Saravanan
Summary: Alcohol dehydrogenases are enzymes that use cofactors for oxidation or reduction reactions of alcohols or carbonyl compounds. They are utilized in green chemistry and have applications in the production of pharmaceuticals. Recombinant enzymes have solved the challenge of producing purified enzymes in large quantities. Engineered alcohol dehydrogenases have been used in asymmetric synthesis in industry. Various methods have been established for regenerating expensive cofactors to make the enzymatic process more efficient and economically viable.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
