Article
Chemistry, Analytical
Tianxiao Yu, Yafang Wang, Huili Quan, Yucui Meng, Zhaohua Wang, Chunchao Zhao, Qing Guo, Jun Ge
Summary: A simple and highly sensitive colorimetric biosensor based on dual DNA-induced cascade hybridization reaction has been developed for detecting SURF1 gene fragments, showing a wide linear range and a low detection limit. The method has been successfully applied to the detection of SURF1 in human serum samples, with potential application prospects in gene fragment analysis and early diagnosis of clinical diseases.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Multidisciplinary
Zhifeng Deng, Cheng Wang, Junqiang Li, Meng Zheng
Summary: This study successfully developed a highly sensitive colorimetric sensor for fluoride ions, which can detect fluoride concentrations with the naked eye, providing new possibilities for fluoride ion detection research.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Analytical
Guo-Ying Chen, Tong-Qing Chai, Jia-Li Wang, Feng-Qing Yang
Summary: Nanomaterials with enzyme-like activity have been widely used in the construction of colorimetric and fluorescence sensors. These sensors offer simple operation and high sensitivity for detecting bioactive small-molecule compounds.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Chemistry, Analytical
Qiaoyin Li, Haiyan Chen, Shumin You, Zhenyu Lin, Zhitao Chen, Fengping Huang, Bin Qiu
Summary: Proper amount of fluorion is important for human health, but excessive fluorion is harmful. A colorimetric and fluorescence enhanced sensor, using MOF material UiO-66 combined with fluorescent dye FITC, is proposed to detect fluorion with high selectivity. It has a good linear relationship in the range of 2-150 mu M (0.038-2.85 ppm), and has been applied to the detection of actual water samples. Field visual detection of fluoride ion is realized, expanding the application of MOF in fluorescence sensing.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Kuan-Neng Chi, Yan Guan, Xi Zhang, Tong Yang, Shuang Meng, Rong Hu, Yun-Hui Yang
Summary: A novel colorimetric strategy based on iodide/metal-organic frameworks (MOF)-mediated amplification was developed for low-cost, naked-eye detection and quantification of H2O2, Cr2O72-, and H2S. The catalytic activity of Cu-MOFs was dramatically enhanced, and the nanocatalyst could act as an amplifier system for target detection. The developed colorimetric strategy provides a new system for detecting low concentrations of analytes in complex biological samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Nanoscience & Nanotechnology
Seunghyeon Kim, Hadley D. Sikes
Summary: A dual photocatalyst signal amplification strategy was developed to achieve time-independent colorimetric biodetection in paper-based tests. By controlling the light dose and improving the photocatalytic efficiency, a 100- to 500-fold enhancement in sensitivity was obtained.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Ju Yeon Kim, Seok Joon Mun, Yoon Ho Roh, Ki Wan Bong
Summary: miRNAs have been highlighted as potential biomarkers for fatal diseases, and colorimetric bead-based assays are gaining attention for practical miRNA detection due to their simplicity. A rapid colorimetric assay based on hydrogel microparticles was presented, showing decreased reaction time and maintained sensitivity with three different miRNA targets. The method was also validated as suitable for multiplex miRNA detection with low cross-reactivity.
Article
Engineering, Environmental
Zhiwei Qiu, Wei Duan, Shoufu Cao, Teng Zeng, Tianyu Zhao, Jiankun Huang, Xiaoqing Lu, Jingbin Zeng
Summary: In this paper, a highly specific colorimetric method for fluoride (F-) using AgPt-Fe3O4 nanozyme was proposed. The method has 100% aqueous compatibility and a low detection limit. The color changes are induced by the oxidation of SiO2 shell, and the method shows high selectivity towards F- over other common anions, making it suitable for analyzing complex sewage samples.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Guangyan Liu, Jun Ling, Hanzhao Xie, Jianping Li
Summary: In this study, a molecularly imprinted polymer-electrochemiluminescence sensor was developed for ultra-sensitive detection of ethiprole using an enzymatic signal amplification strategy. The sensitivity for ethiprole determination was significantly enhanced by marking the ethiprole molecules with glucose oxidase-encapsulated liposomes and catalyzing the reaction to produce H2O2. The sensor showed a linear relationship between ethiprole concentration and ECL signal, with a detection limit lower than other analytical methods. This simplified and improved method allows direct determination of ethiprole without complicated sample treatment procedures.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Tapendu Samanta, Narayan Das, Raja Shunmugam
Summary: A compound was converted for detection of fluoride ions, displaying efficient detection with color change and mechanism explained through spectroscopic and NMR studies.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Review
Chemistry, Analytical
Lingbo Gong, Lin Feng, Youwei Zheng, Yi Luo, Dan Zhu, Jie Chao, Shao Su, Lianhui Wang
Summary: This article reviews the development, preparation principle, sensing application, and future prospects and challenges of MoS2-based nanoprobes.
Article
Chemistry, Multidisciplinary
Obtin Alkhamis, Juan Canoura, Konstantin Bukhryakov, Anamary Tarifa, Anthony P. DeCaprio, Yi Xiao
Summary: Aptamers have great potential as biorecognition elements for sensors, but current aptamer-based assays often lack the required sensitivity and selectivity. This study presents a rational approach to develop colorimetric cyanine dye-displacement assays that can be widely applied to DNA aptamers, accelerating the development and use of mix-and-measure assays for various analytical applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Analytical
Shuaibing Yu, Lianzhi Li, Jinming Kong, Xueji Zhang
Summary: An ultrasensitive DNA sensor based on the photocatalytic atom transfer radical polymerization (photo-ATRP) strategy was developed for early diagnosis and prevention of diseases related to DNA. The sensor, constructed using a metal-free green ATRP reaction strategy, reduces environmental pollution. Under optimal conditions, the sensor showed a linear relationship with the target DNA in a concentration range of 0.1 fM to 10 pM, with a detection limit of 79 aM. This sensor has high sensitivity, is interference-free, and exhibits good stability, demonstrating great potential for practical applications in life science and medical research.
MICROCHEMICAL JOURNAL
(2023)
Article
Spectroscopy
Ziya Aydin, Mustafa Keles
Summary: The study developed two simple colorimetric sensors, BP-Cl and CP-Cl, which showed high sensitivity and selectivity for glyphosate detection through color changes. The sensors were able to monitor glyphosate in water samples using both naked-eye and UV-Vis spectroscopy, demonstrating their potential for practical applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yu Muto, Gen Hirao, Tamotsu Zako
Summary: The study presented a AuNP-based signal-amplifying sandwich biosensor for detecting target molecules without the need for conformational changes in ligands. Thrombin was used as a model target, triggering an extension reaction via hybridization of two probes and subsequently RNA synthesis initiation. The amplified RNA drives aggregation or dispersion of the AuNPs, leading to observable color differences in the solution. This detection system can be universally applied to a wide range of ligands due to its ligand-independent design.
Article
Chemistry, Organic
Faiza Diaba, Gisela Trenchs
Summary: The first violet light-mediated synthesis of gamma- and delta-lactams from N-alkenyl trichloroacetamides is reported in this paper. The reactions are conducted in tetrahydrofuran or 2-methyltetrahydrofuran as the sole solvent without catalysts or additives, under non-anhydrous conditions in an air atmosphere where the solvent serves as the radical initiator.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Feroze Hussain, Sajjad Ahmed, Ashiq Hussain Padder, Qazi Naveed Ahmed
Summary: This study reports a novel and efficient one-pot synthesis method for mixed phosphorotrithioates, which does not require supplementary additives and shows broad applicability.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Hyunjin Oh, Ikyon Kim
Summary: A new 1,2,4-triazole-pyrrolo[1,2-a]pyrazine hybrid system, 6-acylpyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, was synthesized using a catalyst-free method. This method involved sequential exposure of pyrrole-2-carbonitrile-derived substrates to DMF-DMA and acyl hydrazide, resulting in the formation of acylated pyrazine and 1,2,4-triazole rings, enabling the installation of various substituents at specific positions on the core skeleton.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Ming Yan, Si-fan Wang, Yong-po Zhang, Jin-zhong Zhao, Zhuo Tang, Guang-xun Li
Summary: Here we developed an efficient photocatalytic approach for the convenient preparation of sulfinamides. The reaction allows for the gram-scale preparation of sulfinamides and the one-pot synthesis of various sulfonyl amides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Farzaneh Bandehali-Naeini, Zahra Tanbakouchian, Noushin Farajinia-Lehi, Nicolas Mayer, Morteza Shiri, Martin Breugst
Summary: Two tandem catalytic systems were developed for the synthesis of novel 3,4-disubstituted maleimides using the same Ugi adducts. Different maleimide structures can be synthesized using either Pd or Cu catalysis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Article
Chemistry, Organic
Tanya Raghava, Anjan Chattopadhyay, Subhadeep Banerjee, Nivedita Sarkar
Summary: Amine substitution of two ortho fluorine atoms of tetrafluoroterephthalonitrile through SNAr chemistry is easily achievable. But further fluorine substitution is only possible under forcing conditions, yielding valuable fluorophores for bioimaging.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)
Review
Chemistry, Organic
Anju Chadha, Santosh Kumar Padhi, Selvaraj Stella, Sowmyalakshmi Venkataraman, Thangavelu Saravanan
Summary: Alcohol dehydrogenases are enzymes that use cofactors for oxidation or reduction reactions of alcohols or carbonyl compounds. They are utilized in green chemistry and have applications in the production of pharmaceuticals. Recombinant enzymes have solved the challenge of producing purified enzymes in large quantities. Engineered alcohol dehydrogenases have been used in asymmetric synthesis in industry. Various methods have been established for regenerating expensive cofactors to make the enzymatic process more efficient and economically viable.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2024)